Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NFKBIL1
  • Mouse genes Nfkbil1
  • Rat genes Nfkbil1
  • Zfish genes nfkbil1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfkbil1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NFKBIL1	IPI	UniProtKB:Q8WUQ7	Human	PMID:20829348
Molecular Function	GO:0005515	protein binding	NFKBIL1	IPI	UniProtKB:Q9Y5B8	Human	PMID:32296183
Cellular Component	GO:0005829	cytosol	Nfkbil1	IDA		Mouse	PMID:22024480
Cellular Component	GO:0005654	nucleoplasm	NFKBIL1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NFKBIL1	IDA		Human	PMID:20829348
Cellular Component	GO:0005634	nucleus	Nfkbil1	IDA		Mouse	PMID:22024480
Biological Process	GO:0071222	cellular response to lipopolysaccharide	NFKBIL1	IDA		Human	PMID:20829348
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Nfkbil1	IDA		Mouse	PMID:22024480
Biological Process	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway	NFKBIL1	IDA		Human	PMID:20829348
Biological Process	GO:0032088	negative regulation of NF-kappaB transcription factor activity	NFKBIL1	IDA		Human	PMID:20829348
Biological Process	GO:0034122	negative regulation of toll-like receptor signaling pathway	NFKBIL1	IDA		Human	PMID:20829348
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	NFKBIL1	IMP		Human	PMID:20829348

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern