Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NFS1
  • Mouse genes Nfs1
  • Rat genes Nfs1
  • Zfish genes nfs1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfs1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031071	cysteine desulfurase activity	NFS1	IDA		Human	PMID:16527810
Molecular Function	GO:0031071	cysteine desulfurase activity	NFS1	EXP		Human	PMID:20873749
Molecular Function	GO:0031071	cysteine desulfurase activity	NFS1	IDA		Human	PMID:29097656
Molecular Function	GO:0031071	cysteine desulfurase activity	NFS1	IDA		Human	PMID:31664822
Molecular Function	GO:0005515	protein binding	NFS1	IPI	UniProtKB:Q9H1K1	Human	PMID:11060020
Molecular Function	GO:0005515	protein binding	NFS1	IPI	UniProtKB:Q9H1K1	Human	PMID:16527810
Molecular Function	GO:0005515	protein binding	NFS1	IPI	UniProtKB:O95396	Human	PMID:18650437
Molecular Function	GO:0005515	protein binding	NFS1	IPI	UniProtKB:Q9HD34	Human	PMID:18650437
Molecular Function	GO:0005515	protein binding	NFS1	IPI	UniProtKB:Q9H1K1	Human	PMID:23940031
Molecular Function	GO:0005515	protein binding	NFS1	IPI	UniProtKB:Q9HD34	Human	PMID:26342079
Molecular Function	GO:0005515	protein binding	NFS1	IPI	UniProtKB:P38646	Human	PMID:26702583
Molecular Function	GO:0005515	protein binding	NFS1	IPI	UniProtKB:Q9HD34	Human	PMID:27499296
Molecular Function	GO:0005515	protein binding	NFS1	IPI	UniProtKB:Q9NZJ6	Human	PMID:27499296
Molecular Function	GO:0005515	protein binding	NFS1	IPI	UniProtKB:Q6P4F2	Human	PMID:28001042
Molecular Function	GO:0005515	protein binding	NFS1	IPI	UniProtKB:Q9H1K1,UniProtKB:Q9HD34	Human	PMID:29097656
Molecular Function	GO:0005515	protein binding	NFS1	IPI	UniProtKB:O14561,UniProtKB:Q9HD34	Human	PMID:31664822
Molecular Function	GO:0042803	protein homodimerization activity	NFS1	IDA		Human	PMID:16527810
Molecular Function	GO:0042803	protein homodimerization activity	NFS1	IDA		Human	PMID:29097656
Molecular Function	GO:0042803	protein homodimerization activity	NFS1	IDA		Human	PMID:34824239
Cellular Component	GO:0005829	cytosol	NFS1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	NFS1	IDA		Human	PMID:16527810
Cellular Component	GO:0099128	mitochondrial iron-sulfur cluster assembly complex	NFS1	IDA		Human	PMID:21298097
Cellular Component	GO:0099128	mitochondrial iron-sulfur cluster assembly complex	NFS1	IDA		Human	PMID:31101807
Cellular Component	GO:0099128	mitochondrial iron-sulfur cluster assembly complex	Nfs1	IDA		Mouse	MGI:MGI:7327226|PMID:25597503
Cellular Component	GO:0099128	mitochondrial iron-sulfur cluster assembly complex	Nfs1	IDA		Mouse	MGI:MGI:6228237|PMID:21298097
Cellular Component	GO:0005759	mitochondrial matrix	NFS1	IDA		Human	PMID:16847322
Cellular Component	GO:0005759	mitochondrial matrix	Nfs1	IDA		Mouse	PMID:9738949
Cellular Component	GO:0005739	mitochondrion	NFS1	IDA		Human	PMID:26702583
Cellular Component	GO:0005739	mitochondrion	Nfs1	IDA		Mouse	PMID:16787928
Cellular Component	GO:0005739	mitochondrion	Nfs1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Nfs1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005654	nucleoplasm	NFS1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NFS1	IDA		Human	PMID:16847322
Cellular Component	GO:0005634	nucleus	Nfs1	IDA		Mouse	MGI:MGI:3763294|PMID:16847322
Biological Process	GO:0044571	[2Fe-2S] cluster assembly	NFS1	IDA		Human	PMID:24971490
Biological Process	GO:0044571	[2Fe-2S] cluster assembly	NFS1	IDA		Human	PMID:31664822
Biological Process	GO:0044572	[4Fe-4S] cluster assembly	Nfs1	IDA		Mouse	MGI:MGI:7327226|PMID:25597503
Biological Process	GO:0018283	iron incorporation into metallo-sulfur cluster	NFS1	IDA		Human	PMID:16847322
Biological Process	GO:0018283	iron incorporation into metallo-sulfur cluster	Nfs1	IDA		Mouse	MGI:MGI:3763294|PMID:16847322

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern