Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NFYA
  • Mouse genes Nfya
  • Rat genes Nfya
  • Zfish genes nfya,nfyal
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfya

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	NFYA	IDA		Human	PMID:15243141
Molecular Function	GO:0003677	DNA binding	Nfya	IDA		Mouse	PMID:8306889
Molecular Function	GO:0003677	DNA binding	Nfya	IDA		Mouse	PMID:12730328
Molecular Function	GO:0003677	DNA binding	Nfya	IDA		Mouse	PMID:15601870
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Nfya	IMP		Mouse	MGI:MGI:3525928|PMID:15601870
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Nfya	IDA		Mouse	MGI:MGI:3525928|PMID:15601870
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Nfya	IDA		Mouse	PMID:15601870
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Nfya	IDA		Mouse	PMID:12659851
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:Q9UKY1	Human	PMID:10571058
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:Q9H4I2	Human	PMID:12659632
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:Q9Y6X8	Human	PMID:12741956
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:P25208	Human	PMID:15243141
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:Q07955	Human	PMID:15243141
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:Q13952	Human	PMID:15243141
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:Q92624	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:P04637	Human	PMID:16959611
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:P25208	Human	PMID:16959611
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:Q92624	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:Q13952	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:P25208	Human	PMID:23332751
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:Q13952	Human	PMID:23332751
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:P25208	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:P52655	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:P68400	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:Q7Z3K3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:Q9Y383	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:P68400	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:Q9Y383	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NFYA	IPI	UniProtKB:Q13952	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	Nfya	IPI	UniProtKB:P08047	Mouse	MGI:MGI:3687730|PMID:10393239
Molecular Function	GO:0005515	protein binding	Nfya	IPI	PR:P33242	Mouse	PMID:12730328
Molecular Function	GO:0005515	protein binding	Nfya	IPI	UniProtKB:P08047	Rat	PMID:10393239|RGD:8553812
Molecular Function	GO:0005515	protein binding	Nfya	IPI	UniProtKB:Q01714	Rat	PMID:10393239|RGD:8553812
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NFYA	IDA		Human	PMID:11256944
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nfya	IDA		Mouse	MGI:MGI:3525928|PMID:15601870
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nfya	IDA		Mouse	MGI:MGI:5574437|PMID:24030830
Molecular Function	GO:0043565	sequence-specific DNA binding	Nfya	IGI	MGI:MGI:97317	Mouse	PMID:1698608
Molecular Function	GO:0000976	transcription cis-regulatory region binding	NFYA	IDA		Human	PMID:11256944
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Nfya	IDA		Mouse	PMID:15516209
Molecular Function	GO:0001221	transcription coregulator binding	Nfya	IPI	RGD:620036	Rat	PMID:21164521|RGD:7364726
Cellular Component	GO:0016602	CCAAT-binding factor complex	NFYA	IPI		Human	PMID:23332751
Cellular Component	GO:0016602	CCAAT-binding factor complex	NFYA	IDA		Human	PMID:15243141
Cellular Component	GO:0016602	CCAAT-binding factor complex	Nfya	IDA		Rat	PMID:7878029|RGD:729287
Cellular Component	GO:0005654	nucleoplasm	NFYA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NFYA	IDA		Human	PMID:15243141
Cellular Component	GO:0005634	nucleus	NFYA	IDA		Human	PMID:15964792
Cellular Component	GO:0005634	nucleus	Nfya	IDA		Mouse	PMID:22969033
Cellular Component	GO:0005634	nucleus	Nfya	IDA		Mouse	PMID:12659851
Cellular Component	GO:0005634	nucleus	Nfya	IDA		Mouse	PMID:12730328
Cellular Component	GO:0032993	protein-DNA complex	NFYA	IDA		Human	PMID:11256944
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	NFYA	IDA		Human	PMID:11256944
Biological Process	GO:0080182	histone H3-K4 trimethylation	NFYA	IDA		Human	PMID:21445285
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Nfya	IMP		Mouse	MGI:MGI:5574437|PMID:24030830
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Nfya	IDA		Mouse	PMID:15601870
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Nfya	IDA		Mouse	PMID:12730328
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NFYA	IDA		Human	PMID:23332751
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfya	IDA		Mouse	MGI:MGI:5306552|PMID:20861184
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfya	IMP		Mouse	MGI:MGI:3525928|PMID:15601870
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfya	IDA		Mouse	PMID:12659851
Biological Process	GO:0006355	regulation of DNA-templated transcription	NFYA	IDA		Human	PMID:15243141
Biological Process	GO:0035065	regulation of histone acetylation	NFYA	IDA		Human	PMID:21304275

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern