Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NFYC
  • Mouse genes Nfyc
  • Rat genes Nfyc
  • Zfish genes nfyc
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nfyc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	NFYC	IDA		Human	PMID:15243141
Molecular Function	GO:0003677	DNA binding	Nfyc	IDA		Mouse	PMID:15601870
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Nfyc	IDA		Mouse	MGI:MGI:3525928|PMID:15601870
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Nfyc	IDA		Mouse	PMID:15601870
Molecular Function	GO:0005515	protein binding	NFYC	IPI	UniProtKB:P25208	Human	PMID:12401788
Molecular Function	GO:0005515	protein binding	NFYC	IPI	UniProtKB:P23511	Human	PMID:15243141
Molecular Function	GO:0005515	protein binding	NFYC	IPI	UniProtKB:P23511	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	NFYC	IPI	UniProtKB:P25208	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	NFYC	IPI	UniProtKB:P25208	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	NFYC	IPI	UniProtKB:P23511	Human	PMID:23332751
Molecular Function	GO:0005515	protein binding	NFYC	IPI	UniProtKB:P25208	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	NFYC	IPI	UniProtKB:P23511	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	NFYC	IPI	UniProtKB:P25208	Human	PMID:35140242
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NFYC	IDA		Human	PMID:11256944
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nfyc	IDA		Mouse	MGI:MGI:3525928|PMID:15601870
Molecular Function	GO:0000976	transcription cis-regulatory region binding	NFYC	IDA		Human	PMID:11256944
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Nfyc	IDA		Mouse	PMID:15516209
Cellular Component	GO:0016602	CCAAT-binding factor complex	NFYC	IPI		Human	PMID:23332751
Cellular Component	GO:0016602	CCAAT-binding factor complex	NFYC	IDA		Human	PMID:15243141
Cellular Component	GO:0016602	CCAAT-binding factor complex	Nfyc	IDA		Rat	PMID:7878029|RGD:729287
Cellular Component	GO:0005654	nucleoplasm	NFYC	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NFYC	IDA		Human	PMID:15243141
Cellular Component	GO:0005634	nucleus	NFYC	IDA		Human	PMID:15964792
Cellular Component	GO:0005634	nucleus	Nfyc	IDA		Mouse	PMID:19734906
Cellular Component	GO:0032993	protein-DNA complex	NFYC	IDA		Human	PMID:11256944
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	NFYC	IDA		Human	PMID:11256944
Biological Process	GO:0080182	histone H3-K4 trimethylation	NFYC	IDA		Human	PMID:21445285
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Nfyc	IDA		Mouse	PMID:15601870
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NFYC	IDA		Human	PMID:23332751
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nfyc	IDA		Mouse	MGI:MGI:3525928|PMID:15601870
Biological Process	GO:0006355	regulation of DNA-templated transcription	NFYC	IDA		Human	PMID:15243141
Biological Process	GO:0035065	regulation of histone acetylation	NFYC	IDA		Human	PMID:21304275
Biological Process	GO:0060041	retina development in camera-type eye	nfyc	IMP	ZFIN:ZDB-GENO-040720-1	Zfish	PMID:15716491
Biological Process	GO:0060041	retina development in camera-type eye	nfyc	IMP	ZFIN:ZDB-GENO-040720-2	Zfish	PMID:15716491

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern