Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NGEF
  • Mouse genes Ngef
  • Rat genes Ngef
  • Zfish genes ngef
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ngef

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046875	ephrin receptor binding	Ngef	IPI	UniProtKB:Q03137	Mouse	MGI:MGI:3696283|PMID:17143272
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	NGEF	EXP		Human	PMID:15848799
Molecular Function	GO:0005515	protein binding	NGEF	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NGEF	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NGEF	IPI	UniProtKB:P01112	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NGEF	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NGEF	IPI	UniProtKB:P06396	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NGEF	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NGEF	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NGEF	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NGEF	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NGEF	IPI	UniProtKB:Q9Y649	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ngef	IPI	UniProtKB:P61809	Mouse	MGI:MGI:3696283|PMID:17143272
Cellular Component	GO:0098978	glutamatergic synapse	Ngef	IMP		Mouse	PMID:17143272
Cellular Component	GO:0098978	glutamatergic synapse	Ngef	IEP		Mouse	PMID:17143272
Cellular Component	GO:0098978	glutamatergic synapse	Ngef	IDA		Mouse	PMID:17143272
Cellular Component	GO:0098794	postsynapse	Ngef	IDA		Rat	PMID:17143272|RGD:8554385
Biological Process	GO:0048013	ephrin receptor signaling pathway	Ngef	IDA		Mouse	MGI:MGI:3696283|PMID:17143272
Biological Process	GO:0061002	negative regulation of dendritic spine morphogenesis	Ngef	IDA		Mouse	MGI:MGI:3696283|PMID:17143272
Biological Process	GO:0043087	regulation of GTPase activity	Ngef	IDA		Mouse	MGI:MGI:3696283|PMID:17143272
Biological Process	GO:1905806	regulation of synapse pruning	Ngef	IDA		Mouse	PMID:17143272
Biological Process	GO:1905806	regulation of synapse pruning	Ngef	IMP		Mouse	PMID:17143272
Biological Process	GO:1905806	regulation of synapse pruning	Ngef	IEP		Mouse	PMID:17143272

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern