Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ngf

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NGF
- Mouse genes Ngf
- Rat genes Ngf
- Zfish genes ngfa,ngfb
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ngf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008191	metalloendopeptidase inhibitor activity	NGF	IDA		Human	PMID:20164177
Molecular Function	GO:0005163	nerve growth factor receptor binding	NGF	IPI	UniProtKB:Q99523	Human	PMID:14985763
Molecular Function	GO:0005515	protein binding	NGF	IPI	UniProtKB:P04629	Human	PMID:10490030
Molecular Function	GO:0005515	protein binding	NGF	IPI	UniProtKB:P04629	Human	PMID:14985763
Molecular Function	GO:0005515	protein binding	NGF	IPI	UniProtKB:P07174	Human	PMID:14985763
Molecular Function	GO:0005515	protein binding	NGF	IPI	UniProtKB:P08138	Human	PMID:14985763
Molecular Function	GO:0005515	protein binding	NGF	IPI	UniProtKB:Q99523	Human	PMID:14985763
Molecular Function	GO:0005515	protein binding	NGF	IPI	UniProtKB:P07174	Human	PMID:15131306
Molecular Function	GO:0005515	protein binding	NGF	IPI	UniProtKB:P07174	Human	PMID:18596692
Molecular Function	GO:0005515	protein binding	NGF	IPI	UniProtKB:Q99523	Human	PMID:19122660
Molecular Function	GO:0005515	protein binding	NGF	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NGF	IPI	UniProtKB:P20042	Human	PMID:32814053
Molecular Function	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	Ngf	IDA		Mouse	MGI:MGI:5426777\|PMID:19036963
Molecular Function	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity	Ngf	IDA		Mouse	PMID:27655914
Cellular Component	GO:0005615	extracellular space	Ngf	HDA		Mouse	MGI:MGI:5640941\|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Ngf	IDA		Rat	PMID:19065562\|RGD:2303800
Biological Process	GO:0008344	adult locomotory behavior	Ngf	IMP		Rat	PMID:19129380\|RGD:2303796
Biological Process	GO:0007568	aging	Ngf	IEP		Rat	PMID:21559866\|RGD:8693644
Biological Process	GO:0048675	axon extension	Ngf	IMP		Mouse	PMID:8861722
Biological Process	GO:0071229	cellular response to acid chemical	Ngf	IDA		Mouse	PMID:25542970
Biological Process	GO:0007623	circadian rhythm	Ngf	IEP		Mouse	MGI:MGI:5503234\|PMID:23785138
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	Ngf	IDA		Mouse	PMID:14623868
Biological Process	GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	NGF	IDA		Human	PMID:14985763
Biological Process	GO:0006954	inflammatory response	Ngf	IEP		Rat	PMID:19200610\|RGD:2303794
Biological Process	GO:0007613	memory	Ngf	IMP		Rat	PMID:19129380\|RGD:2303796
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Ngf	IGI	MGI:MGI:1345961	Mouse	PMID:24270184
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Ngf	IGI	MGI:MGI:99702	Mouse	PMID:11731452
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Ngf	IMP		Rat	PMID:21541365\|RGD:8554787
Biological Process	GO:2000675	negative regulation of type B pancreatic cell apoptotic process	Ngf	IMP		Rat	PMID:22926925\|RGD:7242848
Biological Process	GO:0038180	nerve growth factor signaling pathway	Ngf	IGI	MGI:MGI:1345961	Mouse	PMID:24270184
Biological Process	GO:0038180	nerve growth factor signaling pathway	Ngf	IGI	MGI:MGI:97383	Mouse	PMID:24270184
Biological Process	GO:0038180	nerve growth factor signaling pathway	Ngf	IDA		Mouse	PMID:7854358
Biological Process	GO:0051402	neuron apoptotic process	Ngf	IGI	MGI:MGI:1345961	Mouse	PMID:24270184
Biological Process	GO:0051402	neuron apoptotic process	Ngf	IMP		Mouse	PMID:14623868
Biological Process	GO:0051402	neuron apoptotic process	Ngf	IGI	MGI:MGI:99702	Mouse	PMID:11731452
Biological Process	GO:0031175	neuron projection development	Ngf	IDA		Mouse	PMID:27655914
Biological Process	GO:0031175	neuron projection development	Ngf	IDA		Rat	PMID:3336364\|RGD:2303812
Biological Process	GO:0048812	neuron projection morphogenesis	NGF	IDA		Human	PMID:17724343
Biological Process	GO:0007422	peripheral nervous system development	Ngf	IMP	MGI:MGI:1857535	Mouse	PMID:14736860
Biological Process	GO:0045773	positive regulation of axon extension	Ngf	IDA		Mouse	PMID:18052984
Biological Process	GO:0045773	positive regulation of axon extension	Ngf	IMP		Mouse	PMID:8861722
Biological Process	GO:0030307	positive regulation of cell growth	Ngf	IDA		Rat	PMID:18973572\|RGD:2303805
Biological Process	GO:0008284	positive regulation of cell population proliferation	Ngf	IDA		Rat	PMID:18846328\|RGD:2303808
Biological Process	GO:0048672	positive regulation of collateral sprouting	Ngf	IDA		Mouse	PMID:18052984
Biological Process	GO:0043388	positive regulation of DNA binding	Ngf	IMP		Mouse	MGI:MGI:6115179\|PMID:10362258
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	Ngf	IDA		Rat	PMID:19029245\|RGD:8553977
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Ngf	IDA		Rat	PMID:17310240\|RGD:1626216
Biological Process	GO:0010628	positive regulation of gene expression	NGF	IMP		Human	PMID:16153003
Biological Process	GO:0010628	positive regulation of gene expression	Ngf	IGI	UniProtKB:A0A0G2K5M1\|UniProtKB:Q01714	Mouse	MGI:MGI:6115179\|PMID:10362258
Biological Process	GO:0010628	positive regulation of gene expression	Ngf	IGI	MGI:MGI:88190	Mouse	PMID:24733831
Biological Process	GO:0045666	positive regulation of neuron differentiation	Ngf	IDA		Rat	PMID:18846328\|RGD:2303808
Biological Process	GO:0014042	positive regulation of neuron maturation	Ngf	IGI	MGI:MGI:1861437	Mouse	PMID:23015435
Biological Process	GO:0014042	positive regulation of neuron maturation	Ngf	IGI	MGI:MGI:1934030	Mouse	PMID:23015435
Biological Process	GO:0014042	positive regulation of neuron maturation	Ngf	IGI	MGI:MGI:102539	Mouse	PMID:23015435
Biological Process	GO:0014042	positive regulation of neuron maturation	Ngf	IDA		Mouse	PMID:23015435
Biological Process	GO:0010976	positive regulation of neuron projection development	Ngf	IGI	UniProtKB:P70425	Mouse	MGI:MGI:2179663\|PMID:11877426
Biological Process	GO:0010976	positive regulation of neuron projection development	Ngf	IDA		Mouse	PMID:23015435
Biological Process	GO:0010976	positive regulation of neuron projection development	Ngf	IGI	MGI:MGI:1934030	Mouse	PMID:23015435
Biological Process	GO:0010976	positive regulation of neuron projection development	Ngf	IGI	MGI:MGI:1861437	Mouse	PMID:23015435
Biological Process	GO:0010976	positive regulation of neuron projection development	Ngf	IGI	MGI:MGI:102539	Mouse	PMID:23015435
Biological Process	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway	Ngf	IDA		Rat	PMID:19029245\|RGD:8553977
Biological Process	GO:0031954	positive regulation of protein autophosphorylation	Ngf	IDA		Rat	PMID:19029245\|RGD:8553977
Biological Process	GO:0032092	positive regulation of protein binding	Ngf	IMP		Rat	PMID:20605787\|RGD:10402036
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Ngf	IDA		Mouse	MGI:MGI:5426777\|PMID:19036963
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Ngf	IDA		Mouse	PMID:27655914
Biological Process	GO:0001934	positive regulation of protein phosphorylation	Ngf	IDA		Rat	PMID:20605787\|RGD:10402036
Biological Process	GO:0031398	positive regulation of protein ubiquitination	Ngf	IDA		Mouse	PMID:24760869
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	Ngf	IDA		Mouse	MGI:MGI:2179663\|PMID:11877426
Biological Process	GO:2000648	positive regulation of stem cell proliferation	Ngf	IDA		Rat	PMID:18846328\|RGD:2303808
Biological Process	GO:0006468	protein phosphorylation	Ngf	IDA		Mouse	PMID:27655914
Biological Process	GO:0045664	regulation of neuron differentiation	Ngf	IDA		Mouse	PMID:16516892
Biological Process	GO:0046928	regulation of neurotransmitter secretion	Ngf	IGI	MGI:MGI:97306	Mouse	PMID:16298082
Biological Process	GO:0051279	regulation of release of sequestered calcium ion into cytosol	Ngf	IGI	MGI:MGI:1345961	Mouse	PMID:24265601
Biological Process	GO:0051602	response to electrical stimulus	Ngf	IEP		Rat	PMID:19059440\|RGD:2303802
Biological Process	GO:0051384	response to glucocorticoid	Ngf	IEP		Rat	PMID:19200610\|RGD:2303794
Biological Process	GO:0032496	response to lipopolysaccharide	Ngf	IEP		Rat	PMID:19012240\|RGD:2303803
Biological Process	GO:0009612	response to mechanical stimulus	Ngf	IEP		Rat	PMID:18981959\|RGD:2303804
Biological Process	GO:0035094	response to nicotine	Ngf	IEP		Rat	PMID:19824047\|RGD:4891065
Biological Process	GO:0014070	response to organic cyclic compound	Ngf	IEP		Rat	PMID:18818126\|RGD:2303810
Biological Process	GO:0010033	response to organic substance	Ngf	IEP		Rat	PMID:19129380\|RGD:2303796
Biological Process	GO:0010033	response to organic substance	Ngf	IEP		Rat	PMID:19816088\|RGD:5144113
Biological Process	GO:0010193	response to ozone	Ngf	IEP		Rat	PMID:21075861\|RGD:5144147
Biological Process	GO:0043434	response to peptide hormone	Ngf	IEP		Rat	PMID:18756821\|RGD:2303811
Biological Process	GO:0009314	response to radiation	Ngf	IEP		Rat	PMID:19065562\|RGD:2303800
Biological Process	GO:0009410	response to xenobiotic stimulus	Ngf	IEP		Rat	PMID:18836171\|RGD:2303809
Biological Process	GO:0009410	response to xenobiotic stimulus	Ngf	IEP		Rat	PMID:18929835\|RGD:2303807
Biological Process	GO:0009410	response to xenobiotic stimulus	Ngf	IEP		Rat	PMID:19200610\|RGD:2303794
Biological Process	GO:0019233	sensory perception of pain	Ngf	IMP	MGI:MGI:1857535	Mouse	PMID:8137419
Biological Process	GO:0019233	sensory perception of pain	Ngf	IMP		Rat	PMID:21169793\|RGD:5144141

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.