Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NGLY1
  • Mouse genes Ngly1
  • Rat genes Ngly1
  • Zfish genes ngly1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ngly1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000224	peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity	NGLY1	IGI	UniProtKB:Q02890	Human	PMID:28826503
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:P54727	Human	PMID:15358861
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:P54727	Human	PMID:22119785
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:O14545	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:P54725	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:P54727	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q14CS0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q96NT3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q9BYV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q9UMX0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q9UMX0-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:P54727	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:O14545	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:P54725	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:P54727	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q14CS0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q96NT3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q9BYV2	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q9UMX0	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:O14545	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:P26367	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:P54725	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:P54727	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q02548	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q14CS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q2NL98	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q6AI39	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q96NT3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q99081-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q99743	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q9BYV2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NGLY1	IPI	UniProtKB:Q9UMX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ngly1	IPI	UniProtKB:Q01853	Mouse	MGI:MGI:5009406|PMID:16709668
Molecular Function	GO:0005515	protein binding	Ngly1	IPI	UniProtKB:P54725	Mouse	MGI:MGI:5512939|PMID:22575648
Molecular Function	GO:0005515	protein binding	Ngly1	IPI	UniProtKB:Q9R049	Mouse	MGI:MGI:5009406|PMID:16709668
Molecular Function	GO:0005515	protein binding	Ngly1	IPI	UniProtKB:Q01853	Mouse	MGI:MGI:6092676|PMID:17496150
Molecular Function	GO:0005515	protein binding	Ngly1	IPI	UniProtKB:P54728	Mouse	MGI:MGI:3054122|PMID:15358861
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Ngly1	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0005737	cytoplasm	NGLY1	IDA		Human	PMID:15358861
Cellular Component	GO:0005737	cytoplasm	Ngly1	IDA		Mouse	MGI:MGI:3054122|PMID:15358861
Biological Process	GO:0071712	ER-associated misfolded protein catabolic process	Ngly1	IMP		Rat	PMID:32259258|RGD:39457703
Biological Process	GO:0006516	glycoprotein catabolic process	NGLY1	IDA		Human	PMID:15358861
Biological Process	GO:0006516	glycoprotein catabolic process	Ngly1	IDA		Mouse	MGI:MGI:3054122|PMID:15358861
Biological Process	GO:0006517	protein deglycosylation	NGLY1	IDA		Human	PMID:28826503
Biological Process	GO:0006517	protein deglycosylation	NGLY1	IGI	UniProtKB:Q02890	Human	PMID:28826503

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern