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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nhlh2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nhlh2
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0001228DNA-binding transcription activator activity, RNA polymerase II-specificNhlh2IDAMouseMGI:MGI:3056835|PMID:15470499
Molecular FunctionGO:0005515protein bindingNHLH2IPIUniProtKB:Q96EB6HumanPMID:22169038
Molecular FunctionGO:0005515protein bindingNHLH2IPIUniProtKB:P13349HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingNHLH2IPIUniProtKB:P15884-3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingNHLH2IPIUniProtKB:Q99081-3HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingNHLH2IPIUniProtKB:Q9H5J8HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingNHLH2IPIUniProtKB:Q9NZI2-2HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingNhlh2IPIUniProtKB:Q923E4MouseMGI:MGI:5302137|PMID:22169038
Molecular FunctionGO:0000978RNA polymerase II cis-regulatory region sequence-specific DNA bindingNhlh2IDAMouseMGI:MGI:3056835|PMID:15470499
Molecular FunctionGO:0000977RNA polymerase II transcription regulatory region sequence-specific DNA bindingNhlh2IDAMouseMGI:MGI:3795052|PMID:18356286
Molecular FunctionGO:0061629RNA polymerase II-specific DNA-binding transcription factor bindingNHLH2IPIUniProtKB:P25791HumanPMID:16314316
Molecular FunctionGO:0061629RNA polymerase II-specific DNA-binding transcription factor bindingNhlh2IPIUniProtKB:P42227MouseMGI:MGI:3795052|PMID:18356286
Molecular FunctionGO:1990837sequence-specific double-stranded DNA bindingNHLH2IDAHumanPMID:28473536
Cellular ComponentGO:0000785chromatinNhlh2IDAMouseMGI:MGI:3795052|PMID:18356286
Biological ProcessGO:0006915apoptotic processNhlh2IGIUniProtKB:Q02576MouseMGI:MGI:3723363|PMID:17573818
Biological ProcessGO:0021535cell migration in hindbrainNhlh2IGIUniProtKB:Q02576MouseMGI:MGI:3723363|PMID:17573818
Biological ProcessGO:0021888hypothalamus gonadotrophin-releasing hormone neuron developmentNhlh2IMPMouseMGI:MGI:5504302|PMID:23785158
Biological ProcessGO:0008584male gonad developmentNhlh2IMPMouseMGI:MGI:86739|PMID:9090387
Biological ProcessGO:0060179male mating behaviorNhlh2IMPMouseMGI:MGI:86739|PMID:9090387
Biological ProcessGO:0042698ovulation cycleNhlh2IMPMGI:MGI:2180391MousePMID:15465527
Biological ProcessGO:0007422peripheral nervous system developmentNhlh2IMPMouseMGI:MGI:3847049|PMID:19436734
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IINhlh2IDAMouseMGI:MGI:3795052|PMID:18356286
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IINhlh2IDAMouseMGI:MGI:3056835|PMID:15470499

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory