Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NISCH
  • Mouse genes Nisch
  • Rat genes Nisch
  • Zfish genes nisch
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nisch

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	NISCH	IPI	UniProtKB:Q9Y2I1	Human	PMID:23386062
Molecular Function	GO:0005178	integrin binding	Nisch	IDA		Mouse	PMID:11121431
Molecular Function	GO:0005515	protein binding	NISCH	IPI	UniProtKB:P05714	Human	PMID:23386062
Molecular Function	GO:0005515	protein binding	NISCH	IPI	UniProtKB:P51151	Human	PMID:23386062
Molecular Function	GO:0005515	protein binding	NISCH	IPI	UniProtKB:P61107	Human	PMID:23386062
Molecular Function	GO:0005515	protein binding	NISCH	IPI	UniProtKB:P51151	Human	PMID:29568061
Cellular Component	GO:0005829	cytosol	NISCH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	NISCH	IDA		Human	PMID:15028622
Cellular Component	GO:0005829	cytosol	Nisch	IDA		Mouse	PMID:11121431
Cellular Component	GO:0045171	intercellular bridge	NISCH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	NISCH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	NISCH	HDA		Human	PMID:19946888
Cellular Component	GO:0015630	microtubule cytoskeleton	NISCH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NISCH	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	NISCH	IDA		Human	PMID:15028622
Biological Process	GO:0030036	actin cytoskeleton organization	Nisch	IDA		Mouse	PMID:11121431
Biological Process	GO:0006006	glucose metabolic process	Nisch	IMP		Rat	PMID:15028595|RGD:1582690
Biological Process	GO:0030336	negative regulation of cell migration	Nisch	IDA		Mouse	PMID:11121431
Biological Process	GO:0048243	norepinephrine secretion	Nisch	IMP		Rat	PMID:15028598|RGD:1582691
Biological Process	GO:0016601	Rac protein signal transduction	Nisch	IDA		Mouse	PMID:11121431
Biological Process	GO:0008217	regulation of blood pressure	Nisch	IMP		Rat	PMID:14975931|RGD:1582689
Biological Process	GO:0032228	regulation of synaptic transmission, GABAergic	Nisch	IMP		Rat	PMID:16467528|RGD:1582692

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern