Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nkd1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NKD1
- Mouse genes Nkd1
- Rat genes Nkd1
- Zfish genes nkd1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nkd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030165	PDZ domain binding	Nkd1	IPI	UniProtKB:P51140	Mouse	MGI:MGI:1934955\|PMID:11356022
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:Q06190-2	Human	PMID:15687260
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:Q06190-1	Human	PMID:16567647
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:Q06190-2	Human	PMID:16567647
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:P26371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:P60328	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:P60371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:P60409	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:P60411	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:Q92997	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:Q9BYQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:Q9BYR9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NKD1	IPI	UniProtKB:Q9UBU8-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Nkd1	IPI	UniProtKB:P51140	Mouse	MGI:MGI:1934955\|PMID:11356022
Molecular Function	GO:0005515	protein binding	Nkd1	IPI	UniProtKB:Q61062	Mouse	MGI:MGI:5437442\|PMID:11274398
Molecular Function	GO:0005515	protein binding	Nkd1	IPI	UniProtKB:Q06190-2	Mouse	MGI:MGI:5437439\|PMID:15687260
Cellular Component	GO:0005737	cytoplasm	nkd1	IDA		Zfish	PMID:21490931
Cellular Component	GO:0005886	plasma membrane	nkd1	IDA		Zfish	PMID:21490931
Cellular Component	GO:0000159	protein phosphatase type 2A complex	NKD1	IDA		Human	PMID:15687260
Biological Process	GO:0060971	embryonic heart tube left/right pattern formation	nkd1	IMP	ZFIN:ZDB-MRPHLNO-101209-4	Zfish	PMID:20858476
Biological Process	GO:0003146	heart jogging	nkd1	IMP	ZFIN:ZDB-MRPHLNO-101209-4	Zfish	PMID:20858476
Biological Process	GO:0070121	Kupffer's vesicle development	nkd1	IMP	ZFIN:ZDB-MRPHLNO-101209-4	Zfish	PMID:20858476
Biological Process	GO:0060972	left/right pattern formation	nkd1	IMP	ZFIN:ZDB-MRPHLNO-101209-4	Zfish	PMID:20858476
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	NKD1	IMP		Human	PMID:15687260
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	NKD1	IGI	RNAcentral:URS00001E2DBC_9606	Human	PMID:27846906
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Nkd1	IDA		Mouse	MGI:MGI:5437442\|PMID:11274398
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Nkd1	IDA		Mouse	MGI:MGI:1934955\|PMID:11356022
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	nkd1	IDA		Zfish	PMID:21490931
Biological Process	GO:1901233	negative regulation of convergent extension involved in axis elongation	Nkd1	IMP		Mouse	MGI:MGI:5437442\|PMID:11274398
Biological Process	GO:0042308	negative regulation of protein import into nucleus	nkd1	IDA		Zfish	PMID:21490931
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	Nkd1	IGI	UniProtKB:Q9VVV9	Mouse	MGI:MGI:1934955\|PMID:11356022
Biological Process	GO:0001839	neural plate morphogenesis	nkd1	IGI	ZFIN:ZDB-GENO-071130-2,ZFIN:ZDB-MRPHLNO-071203-3	Zfish	PMID:17689523
Biological Process	GO:1901231	positive regulation of non-canonical Wnt signaling pathway via JNK cascade	Nkd1	IDA		Mouse	MGI:MGI:5437442\|PMID:11274398
Biological Process	GO:0045732	positive regulation of protein catabolic process	NKD1	IMP		Human	PMID:15687260
Biological Process	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway	Nkd1	IDA		Mouse	MGI:MGI:5437442\|PMID:11274398
Biological Process	GO:0060061	Spemann organizer formation	nkd1	IMP	ZFIN:ZDB-MRPHLNO-071203-3	Zfish	PMID:17689523
Biological Process	GO:0016055	Wnt signaling pathway	nkd1	IGI	ZFIN:ZDB-GENE-980526-332	Zfish	PMID:17689523
Biological Process	GO:0016055	Wnt signaling pathway	nkd1	IMP	ZFIN:ZDB-GENO-980202-228	Zfish	PMID:17689523
Biological Process	GO:0016055	Wnt signaling pathway	nkd1	IGI	ZFIN:ZDB-GENE-990603-12	Zfish	PMID:17689523
Biological Process	GO:0016055	Wnt signaling pathway	nkd1	IMP	ZFIN:ZDB-GENO-071130-1	Zfish	PMID:17689523

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.