Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NKIRAS2
  • Mouse genes Nkiras2
  • Rat genes Nkiras2
  • Zfish genes nkiras2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nkiras2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032794	GTPase activating protein binding	Nkiras2	IPI	PR:A3KGS3	Mouse	PMID:25220458
Molecular Function	GO:0032794	GTPase activating protein binding	Nkiras2	IPI	PR:Q6GYP7	Mouse	PMID:25220458
Biological Process	GO:0006954	inflammatory response	Nkiras2	IGI	MGI:MGI:104752	Mouse	PMID:25220458
Biological Process	GO:0006954	inflammatory response	Nkiras2	IMP	MGI:MGI:6342810	Mouse	PMID:25220458
Biological Process	GO:0048286	lung alveolus development	Nkiras2	IGI	MGI:MGI:1916971	Mouse	PMID:25220458
Biological Process	GO:0032484	Ral protein signal transduction	Nkiras2	IGI	MGI:MGI:1916971	Mouse	PMID:25220458
Biological Process	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	Nkiras2	IMP	MGI:MGI:6342810	Mouse	PMID:25220458
Biological Process	GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	Nkiras2	IGI	MGI:MGI:104752	Mouse	PMID:25220458
Biological Process	GO:0010803	regulation of tumor necrosis factor-mediated signaling pathway	Nkiras2	IGI	MGI:MGI:1314884,MGI:MGI:1916971	Mouse	PMID:25220458
Biological Process	GO:0043129	surfactant homeostasis	Nkiras2	IGI	MGI:MGI:1916971	Mouse	PMID:25220458

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern