Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NLRP5
  • Mouse genes Nlrp5
  • Rat genes Nlrp5
  • Zfish genes si:ch73-168d20.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nlrp5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NLRP5	IPI	UniProtKB:Q02156	Human	PMID:19542546
Molecular Function	GO:0005515	protein binding	NLRP5	IPI	UniProtKB:A6NGQ2	Human	PMID:25542835
Molecular Function	GO:0005515	protein binding	NLRP5	IPI	UniProtKB:Q587J8	Human	PMID:25542835
Molecular Function	GO:0005515	protein binding	NLRP5	IPI	UniProtKB:Q9H808-1	Human	PMID:25542835
Molecular Function	GO:0005515	protein binding	Nlrp5	IPI	UniProtKB:Q9WVB3	Mouse	MGI:MGI:6389592|PMID:31575650
Molecular Function	GO:0005515	protein binding	Nlrp5	IPI	UniProtKB:P18760	Mouse	MGI:MGI:6296386|PMID:25208553
Molecular Function	GO:0005515	protein binding	Nlrp5	IPI	UniProtKB:Q9CWE6,UniProtKB:Q9WVB3|UniProtKB:Q9D0L1	Mouse	MGI:MGI:6467696|PMID:28992324
Molecular Function	GO:0005515	protein binding	Nlrp5	IPI	PR:Q9CWE6	Mouse	PMID:18804437
Molecular Function	GO:0005515	protein binding	Nlrp5	IPI	PR:Q9CWU5	Mouse	PMID:18804437
Molecular Function	GO:0005515	protein binding	Nlrp5	IPI	PR:Q66X22	Mouse	PMID:32413845
Molecular Function	GO:0005515	protein binding	Nlrp5	IPI	PR:Q9CWU5	Mouse	PMID:18057100
Molecular Function	GO:0005515	protein binding	Nlrp5	IPI	PR:Q9CWU5-2	Mouse	PMID:18057100
Molecular Function	GO:0005515	protein binding	Nlrp5	IPI	PR:Q9WVB3	Mouse	PMID:18804437
Molecular Function	GO:0015631	tubulin binding	NLRP5	IPI	UniProtKB:Q13509	Human	PMID:24374158
Cellular Component	GO:0045179	apical cortex	Nlrp5	IDA		Mouse	PMID:18057100
Cellular Component	GO:0005938	cell cortex	Nlrp5	IDA		Mouse	MGI:MGI:6296386|PMID:25208553
Cellular Component	GO:0005938	cell cortex	Nlrp5	IDA		Mouse	MGI:MGI:6389592|PMID:31575650
Cellular Component	GO:0005938	cell cortex	Nlrp5	IDA		Mouse	PMID:18804437
Cellular Component	GO:0005938	cell cortex	Nlrp5	IDA		Mouse	PMID:18057100
Cellular Component	GO:0005938	cell cortex	Nlrp5	IDA		Mouse	PMID:19376971
Cellular Component	GO:0060473	cortical granule	NLRP5	IDA		Human	PMID:19192343
Cellular Component	GO:0005737	cytoplasm	NLRP5	IDA		Human	PMID:19192343
Cellular Component	GO:0005737	cytoplasm	NLRP5	IDA		Human	PMID:19542546
Cellular Component	GO:0005737	cytoplasm	NLRP5	IDA		Human	PMID:25542835
Cellular Component	GO:0005737	cytoplasm	Nlrp5	IDA		Mouse	MGI:MGI:6389592|PMID:31575650
Cellular Component	GO:0005737	cytoplasm	Nlrp5	IDA		Mouse	MGI:MGI:6467696|PMID:28992324
Cellular Component	GO:0005737	cytoplasm	Nlrp5	IDA		Mouse	PMID:20830304
Cellular Component	GO:0005829	cytosol	Nlrp5	IDA		Mouse	PMID:10433232
Cellular Component	GO:0005794	Golgi apparatus	NLRP5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	NLRP5	IDA		Human	PMID:19192343
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	NLRP5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	NLRP5	IDA		Human	PMID:19192343
Cellular Component	GO:0005739	mitochondrion	Nlrp5	IDA		Mouse	MGI:MGI:3036922|PMID:14670992
Cellular Component	GO:0005730	nucleolus	Nlrp5	IDA		Mouse	MGI:MGI:3036922|PMID:14670992
Cellular Component	GO:0005634	nucleus	NLRP5	IDA		Human	PMID:19192343
Cellular Component	GO:0005634	nucleus	NLRP5	IDA		Human	PMID:25542835
Cellular Component	GO:1990917	ooplasm	Nlrp5	IDA		Mouse	PMID:18057100
Cellular Component	GO:0032991	protein-containing complex	Nlrp5	IDA		Mouse	PMID:18804437
Cellular Component	GO:0032991	protein-containing complex	Nlrp5	IDA		Mouse	PMID:18057100
Cellular Component	GO:0106333	subcortical maternal complex	NLRP5	IDA		Human	PMID:25542835
Cellular Component	GO:0106333	subcortical maternal complex	Nlrp5	IDA		Mouse	MGI:MGI:6389592|PMID:31575650
Cellular Component	GO:0106333	subcortical maternal complex	Nlrp5	IDA		Mouse	MGI:MGI:6467696|PMID:28992324
Cellular Component	GO:0106333	subcortical maternal complex	Nlrp5	IDA		Mouse	MGI:MGI:3811945|PMID:18804437
Cellular Component	GO:0106333	subcortical maternal complex	Nlrp5	IDA		Mouse	MGI:MGI:3771666|PMID:18057100
Cellular Component	GO:0106333	subcortical maternal complex	Nlrp5	IDA		Mouse	PMID:32413845
Biological Process	GO:0007015	actin filament organization	Nlrp5	IMP		Mouse	MGI:MGI:6296386|PMID:25208553
Biological Process	GO:0009887	animal organ morphogenesis	Nlrp5	IMP		Mouse	PMID:10754103
Biological Process	GO:0060471	cortical granule exocytosis	Nlrp5	IMP		Mouse	MGI:MGI:6323780|PMID:31118423
Biological Process	GO:0007566	embryo implantation	Nlrp5	IMP	MGI:MGI:2178449	Mouse	PMID:18804437
Biological Process	GO:0051656	establishment of organelle localization	Nlrp5	IMP		Mouse	MGI:MGI:6323780|PMID:31118423
Biological Process	GO:0051656	establishment of organelle localization	Nlrp5	IMP		Mouse	MGI:MGI:5553206|PMID:24374158
Biological Process	GO:0051293	establishment of spindle localization	Nlrp5	IMP		Mouse	MGI:MGI:6296386|PMID:25208553
Biological Process	GO:0006887	exocytosis	Nlrp5	IMP		Mouse	MGI:MGI:5553206|PMID:24374158
Biological Process	GO:0009566	fertilization	Nlrp5	IMP	MGI:MGI:2178449	Mouse	PMID:11062459
Biological Process	GO:0009566	fertilization	Nlrp5	IMP	MGI:MGI:2178449	Mouse	PMID:18804437
Biological Process	GO:0001701	in utero embryonic development	Nlrp5	IMP	MGI:MGI:2178449	Mouse	PMID:11062459
Biological Process	GO:0001701	in utero embryonic development	Nlrp5	IMP	MGI:MGI:2178449	Mouse	PMID:18804437
Biological Process	GO:0040019	positive regulation of embryonic development	Nlrp5	IMP		Mouse	MGI:MGI:5430272|PMID:22357545
Biological Process	GO:0008104	protein localization	Nlrp5	IMP	MGI:MGI:2178449	Mouse	PMID:20830304
Biological Process	GO:0065003	protein-containing complex assembly	Nlrp5	IMP	MGI:MGI:2178449	Mouse	PMID:18804437
Biological Process	GO:0051302	regulation of cell division	Nlrp5	IMP		Mouse	MGI:MGI:6296386|PMID:25208553
Biological Process	GO:0032879	regulation of localization	Nlrp5	IMP		Mouse	MGI:MGI:5430272|PMID:22357545
Biological Process	GO:0031647	regulation of protein stability	Nlrp5	IMP	MGI:MGI:2178449	Mouse	PMID:18057100
Biological Process	GO:0043487	regulation of RNA stability	Nlrp5	IMP	MGI:MGI:2178449	Mouse	PMID:11062459

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern