Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NLRP9
  • Mouse genes Nlrp9b
  • Rat genes Nlrp9
  • Zfish genes si:ch211-187g4.1,si:ch211-196h16.5,si:dkey-121n8.7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nlrp9b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NLRP9	IPI	UniProtKB:Q08211|UniProtKB:Q9ULZ3	Human	PMID:28636595
Molecular Function	GO:0005515	protein binding	Nlrp9b	IPI	PR:Q9R1M5	Mouse	PMID:32413845
Molecular Function	GO:0005515	protein binding	Nlrp9b	IPI	PR:Q9CWU5	Mouse	PMID:32413845
Molecular Function	GO:0005515	protein binding	Nlrp9b	IPI	PR:Q9CWE6	Mouse	PMID:32413845
Cellular Component	GO:0061702	canonical inflammasome complex	NLRP9	IDA		Human	PMID:28636595
Biological Process	GO:0001824	blastocyst development	Nlrp9b	IGI	MGI:MGI:2675292,MGI:MGI:3028627	Mouse	PMID:32413845
Biological Process	GO:0051607	defense response to virus	Nlrp9b	IMP		Mouse	MGI:MGI:5908739|PMID:28636595
Biological Process	GO:0045087	innate immune response	Nlrp9b	IMP		Mouse	MGI:MGI:5908739|PMID:28636595
Biological Process	GO:0032741	positive regulation of interleukin-18 production	Nlrp9b	IMP		Mouse	MGI:MGI:5908739|PMID:28636595
Biological Process	GO:0070269	pyroptosis	Nlrp9b	IMP		Mouse	MGI:MGI:5908739|PMID:28636595

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern