Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NME8
  • Mouse genes Nme8
  • Rat genes Nme8
  • Zfish genes nme9
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nme8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008017	microtubule binding	NME8	IDA		Human	PMID:17360648
Cellular Component	GO:0005930	axoneme	Nme8	IDA		Mouse	MGI:MGI:2680785|PMID:12909633
Cellular Component	GO:0005737	cytoplasm	NME8	IDA		Human	PMID:11737268
Cellular Component	GO:0005737	cytoplasm	Nme8	IDA		Mouse	MGI:MGI:2680785|PMID:12909633
Cellular Component	GO:0005829	cytosol	NME8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	NME8	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NME8	IDA		Human	PMID:11737268
Cellular Component	GO:0036157	outer dynein arm	NME8	IMP		Human	PMID:17360648
Cellular Component	GO:0097598	sperm cytoplasmic droplet	Nme8	IDA		Mouse	PMID:12909633
Cellular Component	GO:0035686	sperm fibrous sheath	Nme8	IDA		Rat	PMID:12909633|RGD:1299632
Cellular Component	GO:0097225	sperm midpiece	NME8	IDA		Human	PMID:11737268
Cellular Component	GO:0097228	sperm principal piece	NME8	IDA		Human	PMID:11737268
Cellular Component	GO:0097228	sperm principal piece	Nme8	IDA		Mouse	PMID:12909633
Biological Process	GO:0034614	cellular response to reactive oxygen species	Nme8	IGI	MGI:MGI:2389312	Mouse	PMID:23707457
Biological Process	GO:0060271	cilium assembly	NME8	IMP		Human	PMID:17360648
Biological Process	GO:0030317	flagellated sperm motility	Nme8	IGI	MGI:MGI:2389312	Mouse	PMID:23707457

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern