Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NMNAT2
  • Mouse genes Nmnat2
  • Rat genes Nmnat2
  • Zfish genes nmnat2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nmnat2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004515	nicotinate-nucleotide adenylyltransferase activity	NMNAT2	IDA		Human	PMID:16118205
Molecular Function	GO:0140768	protein ADP-ribosyltransferase-substrate adaptor activity	NMNAT2	IDA		Human	PMID:34314702
Molecular Function	GO:0045182	translation regulator activity	NMNAT2	IDA		Human	PMID:34314702
Cellular Component	GO:0005737	cytoplasm	Nmnat2	IDA		Rat	PMID:22449973|RGD:13782043
Cellular Component	GO:0005829	cytosol	NMNAT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	NMNAT2	IDA		Human	PMID:16118205
Cellular Component	GO:0005794	Golgi apparatus	Nmnat2	IDA		Mouse	PMID:20943658
Cellular Component	GO:0005770	late endosome	Nmnat2	IDA		Mouse	PMID:20943658
Cellular Component	GO:0045202	synapse	Nmnat2	IDA		Mouse	PMID:20943658
Cellular Component	GO:0005802	trans-Golgi network	Nmnat2	IDA		Mouse	PMID:20943658
Biological Process	GO:0007568	aging	Nmnat2	IEP		Rat	PMID:22449973|RGD:13782043
Biological Process	GO:1904385	cellular response to angiotensin	Nmnat2	IEP		Rat	PMID:22449973|RGD:13782043
Biological Process	GO:0009435	NAD biosynthetic process	Nmnat2	IMP		Rat	PMID:22449973|RGD:13782043
Biological Process	GO:2000766	negative regulation of cytoplasmic translation	NMNAT2	IDA		Human	PMID:34314702

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern