Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NNT
  • Mouse genes Nnt
  • Rat genes Nnt
  • Zfish genes nnt,nnt2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nnt

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050661	NADP binding	NNT	IDA		Human	PMID:10673423
Cellular Component	GO:0016020	membrane	NNT	HDA		Human	PMID:19946888
Cellular Component	GO:0005743	mitochondrial inner membrane	Nnt	HDA		Mouse	PMID:12865426
Cellular Component	GO:0005739	mitochondrion	NNT	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005739	mitochondrion	Nnt	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Nnt	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Nnt	IDA		Rat	PMID:24722990|RGD:13513981
Biological Process	GO:0045454	cell redox homeostasis	Nnt	IMP		Rat	PMID:22198343|RGD:13513982
Biological Process	GO:0098869	cellular oxidant detoxification	Nnt	IMP		Rat	PMID:22198343|RGD:13513982
Biological Process	GO:0032364	intracellular oxygen homeostasis	Nnt	IMP		Rat	PMID:24722990|RGD:13513981
Biological Process	GO:0006740	NADPH regeneration	Nnt	IMP		Rat	PMID:22198343|RGD:13513982
Biological Process	GO:0043066	negative regulation of apoptotic process	Nnt	IMP		Rat	PMID:22198343|RGD:13513982
Biological Process	GO:0001933	negative regulation of protein phosphorylation	Nnt	IMP		Rat	PMID:22198343|RGD:13513982
Biological Process	GO:1903285	positive regulation of hydrogen peroxide catabolic process	Nnt	IMP		Rat	PMID:24722990|RGD:13513981
Biological Process	GO:0010918	positive regulation of mitochondrial membrane potential	Nnt	IMP		Rat	PMID:24722990|RGD:13513981
Biological Process	GO:0072593	reactive oxygen species metabolic process	NNT	IMP		Human	PMID:22634753
Biological Process	GO:0033273	response to vitamin	Nnt	IEP		Rat	PMID:25761734|RGD:13513980

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern