Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NODAL
  • Mouse genes Nodal
  • Rat genes Nodal
  • Zfish genes ndr1,ndr2,spaw
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nodal

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NODAL	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Nodal	IPI	UniProtKB:P0CG37|UniProtKB:P51865	Mouse	MGI:MGI:5318034|PMID:12052855
Molecular Function	GO:0005515	protein binding	Nodal	IPI	UniProtKB:Q64280	Mouse	MGI:MGI:3042530|PMID:15062104
Molecular Function	GO:0005515	protein binding	ndr1	IPI	UniProtKB:P51865	Zfish	PMID:14966532|ZFIN:ZDB-PUB-200522-14
Molecular Function	GO:0005515	protein binding	spaw	IPI	ZFIN:ZDB-GENE-980526-389	Zfish	PMID:30446628
Molecular Function	GO:0048018	receptor ligand activity	Nodal	IDA		Mouse	MGI:MGI:5318034|PMID:12052855
Molecular Function	GO:0070698	type I activin receptor binding	NODAL	IMP		Human	PMID:21356369
Cellular Component	GO:0005576	extracellular region	Nodal	IDA		Mouse	MGI:MGI:5318034|PMID:12052855
Cellular Component	GO:0005615	extracellular space	NODAL	IDA		Human	PMID:21656830
Cellular Component	GO:0032991	protein-containing complex	ndr2	IPI	ZFIN:ZDB-GENE-980526-389	Zfish	PMID:29140251
Cellular Component	GO:0032991	protein-containing complex	ndr1	IPI	ZFIN:ZDB-GENE-980526-389	Zfish	PMID:29140251
Biological Process	GO:0048646	anatomical structure formation involved in morphogenesis	Nodal	IMP	MGI:MGI:1856970	Mouse	PMID:7924997
Biological Process	GO:0009887	animal organ morphogenesis	ndr2	IMP	ZFIN:ZDB-GENO-980202-338	Zfish	PMID:12642489
Biological Process	GO:0009948	anterior/posterior axis specification	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0008595	anterior/posterior axis specification, embryo	ndr1	IMP	ZFIN:ZDB-GENO-091105-1	Zfish	PMID:19046963
Biological Process	GO:0009952	anterior/posterior pattern specification	Nodal	IMP	MGI:MGI:2656539,MGI:MGI:3056345	Mouse	PMID:15302604
Biological Process	GO:0009952	anterior/posterior pattern specification	Nodal	IGI	MGI:MGI:106676	Mouse	PMID:16496285
Biological Process	GO:0009952	anterior/posterior pattern specification	Nodal	IMP	MGI:MGI:2180793	Mouse	PMID:11418863
Biological Process	GO:0009952	anterior/posterior pattern specification	Nodal	IMP	MGI:MGI:2180793	Mouse	PMID:15004567
Biological Process	GO:0009952	anterior/posterior pattern specification	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0009952	anterior/posterior pattern specification	ndr2	IGI	ZFIN:ZDB-GENO-010426-2,ZFIN:ZDB-GENO-980202-1194	Zfish	PMID:12588855
Biological Process	GO:0048327	axial mesodermal cell fate specification	Nodal	IMP		Mouse	PMID:14511481
Biological Process	GO:0007420	brain development	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0048854	brain morphogenesis	ndr2	IMP	ZFIN:ZDB-GENO-120224-2	Zfish	PMID:9007238
Biological Process	GO:0043010	camera-type eye development	ndr1	IMP	ZFIN:ZDB-GENO-201221-3	Zfish	PMID:30620332
Biological Process	GO:0043010	camera-type eye development	ndr1	IMP	ZFIN:ZDB-GENO-071214-5	Zfish	PMID:17692308
Biological Process	GO:0030154	cell differentiation	Nodal	IDA		Mouse	PMID:11456449
Biological Process	GO:0045165	cell fate commitment	Nodal	IMP	MGI:MGI:2668418	Mouse	PMID:12842913
Biological Process	GO:0045165	cell fate commitment	ndr2	IGI	ZFIN:ZDB-GENE-980528-2059	Zfish	PMID:12879074
Biological Process	GO:0001709	cell fate determination	ndr2	IMP	ZFIN:ZDB-GENO-980202-338	Zfish	PMID:12642489
Biological Process	GO:0016477	cell migration	Nodal	IMP	MGI:MGI:2176174,MGI:MGI:3056345	Mouse	PMID:15302604
Biological Process	GO:0042074	cell migration involved in gastrulation	Nodal	IDA		Mouse	PMID:15004567
Biological Process	GO:0008283	cell population proliferation	Nodal	IMP	MGI:MGI:2180793	Mouse	PMID:15004567
Biological Process	GO:0071907	determination of digestive tract left/right asymmetry	spaw	IMP	ZFIN:ZDB-GENO-150730-1	Zfish	PMID:24212328
Biological Process	GO:0048263	determination of dorsal identity	ndr1	IDA		Zfish	PMID:21145463
Biological Process	GO:0061371	determination of heart left/right asymmetry	spaw	IMP	ZFIN:ZDB-GENO-150831-15	Zfish	PMID:25100766
Biological Process	GO:0035462	determination of left/right asymmetry in diencephalon	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-1	Zfish	PMID:19363156
Biological Process	GO:0035462	determination of left/right asymmetry in diencephalon	spaw	IMP	ZFIN:ZDB-GENO-150730-1	Zfish	PMID:24212328
Biological Process	GO:0035462	determination of left/right asymmetry in diencephalon	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-2	Zfish	PMID:12702646
Biological Process	GO:0035462	determination of left/right asymmetry in diencephalon	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-1	Zfish	PMID:12702646
Biological Process	GO:0003140	determination of left/right asymmetry in lateral mesoderm	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-2	Zfish	PMID:12702646
Biological Process	GO:0003140	determination of left/right asymmetry in lateral mesoderm	spaw	IGI	ZFIN:ZDB-MRPHLNO-060112-1,ZFIN:ZDB-MRPHLNO-060718-1	Zfish	PMID:15084459
Biological Process	GO:0003140	determination of left/right asymmetry in lateral mesoderm	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-1	Zfish	PMID:12702646
Biological Process	GO:0003140	determination of left/right asymmetry in lateral mesoderm	ndr1	IMP	ZFIN:ZDB-GENO-000913-1	Zfish	PMID:12702646
Biological Process	GO:0007368	determination of left/right symmetry	Nodal	IDA		Mouse	PMID:12654299
Biological Process	GO:0007368	determination of left/right symmetry	Nodal	IGI	MGI:MGI:106676	Mouse	PMID:16496285
Biological Process	GO:0007368	determination of left/right symmetry	Nodal	IGI	MGI:MGI:1344365	Mouse	PMID:15466485
Biological Process	GO:0007368	determination of left/right symmetry	Nodal	IMP	MGI:MGI:2180793	Mouse	PMID:12231623
Biological Process	GO:0007368	determination of left/right symmetry	Nodal	IMP	MGI:MGI:2388004	Mouse	PMID:12231623
Biological Process	GO:0007368	determination of left/right symmetry	Nodal	IDA		Mouse	PMID:12642485
Biological Process	GO:0007368	determination of left/right symmetry	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0007368	determination of left/right symmetry	Nodal	IGI	MGI:MGI:2443893	Mouse	PMID:28182636
Biological Process	GO:0007368	determination of left/right symmetry	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-1,ZFIN:ZDB-MRPHLNO-060112-2	Zfish	PMID:18267096
Biological Process	GO:0007368	determination of left/right symmetry	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-1	Zfish	PMID:17678853
Biological Process	GO:0007368	determination of left/right symmetry	spaw	IMP	ZFIN:ZDB-MRPHLNO-090225-2	Zfish	PMID:18784369
Biological Process	GO:0007368	determination of left/right symmetry	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-2	Zfish	PMID:17592620
Biological Process	GO:0007368	determination of left/right symmetry	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-2	Zfish	PMID:16207761
Biological Process	GO:0007368	determination of left/right symmetry	spaw	IMP		Zfish	PMID:14576439
Biological Process	GO:0007368	determination of left/right symmetry	ndr2	IMP	ZFIN:ZDB-GENO-991201-21	Zfish	PMID:10903181
Biological Process	GO:0007368	determination of left/right symmetry	ndr2	IMP	ZFIN:ZDB-GENO-980202-1194	Zfish	PMID:9334285
Biological Process	GO:0007368	determination of left/right symmetry	ndr2	IMP	ZFIN:ZDB-GENO-980202-1194	Zfish	PMID:10903181
Biological Process	GO:0071910	determination of liver left/right asymmetry	spaw	IMP	ZFIN:ZDB-GENO-150730-1	Zfish	PMID:24212328
Biological Process	GO:0035469	determination of pancreatic left/right asymmetry	spaw	IMP	ZFIN:ZDB-GENO-150730-1	Zfish	PMID:24212328
Biological Process	GO:0035469	determination of pancreatic left/right asymmetry	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-1	Zfish	PMID:12702646
Biological Process	GO:0035469	determination of pancreatic left/right asymmetry	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-2	Zfish	PMID:12702646
Biological Process	GO:0055123	digestive system development	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0048565	digestive tract development	ndr1	IMP		Zfish	PMID:27545838
Biological Process	GO:0048546	digestive tract morphogenesis	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0009950	dorsal/ventral axis specification	ndr1	IMP	ZFIN:ZDB-MRPHLNO-051228-1	Zfish	PMID:16355228
Biological Process	GO:0009950	dorsal/ventral axis specification	ndr1	IMP	ZFIN:ZDB-MRPHLNO-051228-3	Zfish	PMID:16355228
Biological Process	GO:0009950	dorsal/ventral axis specification	ndr1	IMP	ZFIN:ZDB-MRPHLNO-051228-2	Zfish	PMID:16355228
Biological Process	GO:0009953	dorsal/ventral pattern formation	ndr2	IMP	ZFIN:ZDB-MRPHLNO-060930-4	Zfish	PMID:22522081
Biological Process	GO:0009953	dorsal/ventral pattern formation	ndr2	IDA		Zfish	PMID:22522081
Biological Process	GO:0009953	dorsal/ventral pattern formation	ndr2	IDA		Zfish	PMID:10704853
Biological Process	GO:0009953	dorsal/ventral pattern formation	ndr1	IDA		Zfish	PMID:10704853
Biological Process	GO:0009953	dorsal/ventral pattern formation	ndr1	IDA		Zfish	PMID:22522081
Biological Process	GO:0009953	dorsal/ventral pattern formation	ndr1	IMP		Zfish	PMID:9698446
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0048048	embryonic eye morphogenesis	ndr2	IMP	ZFIN:ZDB-CRISPR-190513-7	Zfish	PMID:30555080
Biological Process	GO:0048048	embryonic eye morphogenesis	ndr2	IMP	ZFIN:ZDB-GENO-980202-338	Zfish	PMID:12642489
Biological Process	GO:0048048	embryonic eye morphogenesis	ndr2	IMP	ZFIN:ZDB-CRISPR-190513-2	Zfish	PMID:30555080
Biological Process	GO:0048048	embryonic eye morphogenesis	ndr2	IMP	ZFIN:ZDB-CRISPR-190513-12	Zfish	PMID:30555080
Biological Process	GO:0048048	embryonic eye morphogenesis	ndr2	IMP	ZFIN:ZDB-CRISPR-190513-3	Zfish	PMID:30555080
Biological Process	GO:0035050	embryonic heart tube development	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0035050	embryonic heart tube development	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-1,ZFIN:ZDB-MRPHLNO-060112-2	Zfish	PMID:18267096
Biological Process	GO:0060971	embryonic heart tube left/right pattern formation	spaw	IMP	ZFIN:ZDB-GENO-060608-121	Zfish	ZFIN:ZDB-PUB-100730-1
Biological Process	GO:0003143	embryonic heart tube morphogenesis	ndr2	IMP	ZFIN:ZDB-GENO-980202-1194	Zfish	PMID:9334285
Biological Process	GO:0009880	embryonic pattern specification	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0001892	embryonic placenta development	Nodal	IMP	MGI:MGI:1856970	Mouse	PMID:11456449
Biological Process	GO:0001892	embryonic placenta development	Nodal	IMP	MGI:MGI:2158730	Mouse	PMID:11456449
Biological Process	GO:0060136	embryonic process involved in female pregnancy	Nodal	IMP	MGI:MGI:1856970	Mouse	PMID:11456449
Biological Process	GO:0060136	embryonic process involved in female pregnancy	Nodal	IMP	MGI:MGI:2158730	Mouse	PMID:11456449
Biological Process	GO:0031018	endocrine pancreas development	ndr1	IMP		Zfish	PMID:27545838
Biological Process	GO:0007492	endoderm development	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0035987	endodermal cell differentiation	NODAL	IMP		Human	PMID:21741376
Biological Process	GO:0060802	epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification	Nodal	IMP		Mouse	PMID:14511481
Biological Process	GO:0061966	establishment of left/right asymmetry	spaw	IMP	ZFIN:ZDB-GENO-190830-4	Zfish	PMID:30446628
Biological Process	GO:0061966	establishment of left/right asymmetry	spaw	IGI	ZFIN:ZDB-GENO-190830-7	Zfish	PMID:30446628
Biological Process	GO:0061966	establishment of left/right asymmetry	spaw	IGI	ZFIN:ZDB-GENO-190830-6	Zfish	PMID:30446628
Biological Process	GO:0061966	establishment of left/right asymmetry	spaw	IGI	ZFIN:ZDB-GENO-190830-5	Zfish	PMID:30446628
Biological Process	GO:0061966	establishment of left/right asymmetry	spaw	IMP	ZFIN:ZDB-GENO-190830-3	Zfish	PMID:30446628
Biological Process	GO:0061966	establishment of left/right asymmetry	spaw	IMP	ZFIN:ZDB-GENO-190830-2	Zfish	PMID:30446628
Biological Process	GO:0007565	female pregnancy	Nodal	IEP		Rat	PMID:31418961|RGD:155230829
Biological Process	GO:0033504	floor plate development	ndr2	IMP	ZFIN:ZDB-GENO-980202-163	Zfish	PMID:9007234
Biological Process	GO:0033504	floor plate development	ndr2	IMP	ZFIN:ZDB-GENO-980202-338	Zfish	PMID:9007234
Biological Process	GO:0033504	floor plate development	ndr2	IMP	ZFIN:ZDB-GENO-120224-2	Zfish	PMID:9007234
Biological Process	GO:0021508	floor plate formation	ndr2	IMP	ZFIN:ZDB-GENO-980202-332	Zfish	PMID:12508225
Biological Process	GO:0021508	floor plate formation	ndr2	IMP	ZFIN:ZDB-GENO-980202-1194	Zfish	PMID:12508225
Biological Process	GO:0021508	floor plate formation	ndr2	IMP	ZFIN:ZDB-GENO-980202-1194	Zfish	PMID:10694427
Biological Process	GO:0033505	floor plate morphogenesis	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0048859	formation of anatomical boundary	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0007369	gastrulation	Nodal	IMP		Mouse	PMID:14511481
Biological Process	GO:0007369	gastrulation	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0001702	gastrulation with mouth forming second	Nodal	IMP	MGI:MGI:1856970	Mouse	PMID:14607953
Biological Process	GO:0007281	germ cell development	Nodal	IMP	MGI:MGI:2158730	Mouse	PMID:23034635
Biological Process	GO:0007507	heart development	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0003146	heart jogging	spaw	IMP	ZFIN:ZDB-MRPHLNO-090225-2	Zfish	PMID:18784369
Biological Process	GO:0001947	heart looping	Nodal	IGI	MGI:MGI:106676	Mouse	PMID:16496285
Biological Process	GO:0001947	heart looping	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-1	Zfish	PMID:12702646
Biological Process	GO:0001947	heart looping	spaw	IMP	ZFIN:ZDB-GENO-060608-121	Zfish	ZFIN:ZDB-PUB-100730-1
Biological Process	GO:0001947	heart looping	ndr2	IMP	ZFIN:ZDB-GENO-980202-1194	Zfish	PMID:9334285
Biological Process	GO:0021854	hypothalamus development	ndr2	IMP		Zfish	PMID:11239427
Biological Process	GO:0021854	hypothalamus development	ndr1	IMP	ZFIN:ZDB-GENO-071214-5	Zfish	PMID:12070082
Biological Process	GO:0001701	in utero embryonic development	Nodal	IMP	MGI:MGI:2180793	Mouse	PMID:15485907
Biological Process	GO:0001701	in utero embryonic development	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0002085	inhibition of neuroepithelial cell differentiation	Nodal	IMP	MGI:MGI:2180793	Mouse	PMID:16678814
Biological Process	GO:0048839	inner ear development	ndr2	IGI	ZFIN:ZDB-GENO-010426-2,ZFIN:ZDB-GENO-980202-1194	Zfish	PMID:12588855
Biological Process	GO:0048368	lateral mesoderm development	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-1	Zfish	PMID:18985756
Biological Process	GO:0060460	left lung morphogenesis	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0046619	lens placode formation involved in camera-type eye formation	ndr2	IMP	ZFIN:ZDB-GENO-120224-2	Zfish	PMID:9007234
Biological Process	GO:0046619	lens placode formation involved in camera-type eye formation	ndr2	IMP	ZFIN:ZDB-GENO-980202-163	Zfish	PMID:9007234
Biological Process	GO:0046619	lens placode formation involved in camera-type eye formation	ndr2	IMP	ZFIN:ZDB-GENO-980202-338	Zfish	PMID:9007234
Biological Process	GO:0001889	liver development	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0001889	liver development	ndr1	IMP		Zfish	PMID:27545838
Biological Process	GO:0030324	lung development	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0001893	maternal placenta development	Nodal	IMP	MGI:MGI:3056345,MGI:MGI:3576366	Mouse	PMID:22378764
Biological Process	GO:0060137	maternal process involved in parturition	Nodal	IMP	MGI:MGI:3056345,MGI:MGI:3576366	Mouse	PMID:22378764
Biological Process	GO:0048382	mesendoderm development	NODAL	IMP		Human	PMID:21741376
Biological Process	GO:0048382	mesendoderm development	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0048382	mesendoderm development	Nodal	IMP		Mouse	PMID:14511481
Biological Process	GO:0048382	mesendoderm development	ndr2	IMP	ZFIN:ZDB-GENO-980202-338	Zfish	PMID:12642489
Biological Process	GO:0048382	mesendoderm development	ndr1	IMP	ZFIN:ZDB-GENO-000913-1	Zfish	PMID:12642489
Biological Process	GO:0007498	mesoderm development	ndr1	IGI	ZFIN:ZDB-GENE-990630-14	Zfish	PMID:28687631
Biological Process	GO:0001707	mesoderm formation	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0001707	mesoderm formation	ndr2	IMP		Zfish	PMID:18579681
Biological Process	GO:0060766	negative regulation of androgen receptor signaling pathway	NODAL	IDA		Human	PMID:21656830
Biological Process	GO:0010721	negative regulation of cell development	Nodal	IMP	MGI:MGI:2158730	Mouse	PMID:23034635
Biological Process	GO:0045596	negative regulation of cell differentiation	Nodal	IDA		Mouse	PMID:11456449
Biological Process	GO:1901383	negative regulation of chorionic trophoblast cell proliferation	NODAL	IDA		Human	PMID:15150278
Biological Process	GO:2000242	negative regulation of reproductive process	Nodal	IMP	MGI:MGI:2158730	Mouse	PMID:23034635
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nodal	IDA		Mouse	PMID:11456449
Biological Process	GO:1901164	negative regulation of trophoblast cell migration	NODAL	IDA		Human	PMID:21356369
Biological Process	GO:0007399	nervous system development	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0001842	neural fold formation	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0038092	nodal signaling pathway	Nodal	IMP		Mouse	MGI:MGI:5318034|PMID:12052855
Biological Process	GO:1900164	nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	Nodal	IMP		Mouse	MGI:MGI:5315339|PMID:17507406
Biological Process	GO:0030903	notochord development	ndr2	IMP	ZFIN:ZDB-GENO-980202-338	Zfish	PMID:9007234
Biological Process	GO:0030903	notochord development	ndr2	IMP	ZFIN:ZDB-GENO-980202-163	Zfish	PMID:9007234
Biological Process	GO:0030903	notochord development	ndr2	IMP	ZFIN:ZDB-GENO-120224-2	Zfish	PMID:9007234
Biological Process	GO:0014028	notochord formation	ndr2	IDA		Zfish	PMID:17208216
Biological Process	GO:0060037	pharyngeal system development	ndr1	IMP		Zfish	PMID:27545838
Biological Process	GO:0001890	placenta development	NODAL	IMP		Human	PMID:21356369
Biological Process	GO:0010085	polarity specification of proximal/distal axis	Nodal	IMP		Mouse	PMID:14511481
Biological Process	GO:0032927	positive regulation of activin receptor signaling pathway	NODAL	IGI	UniProtKB:Q8NER5	Human	PMID:15150278
Biological Process	GO:0045766	positive regulation of angiogenesis	NODAL	IMP		Human	PMID:21116837
Biological Process	GO:0045766	positive regulation of angiogenesis	Nodal	IMP		Mouse	MGI:MGI:5430856|PMID:21116837
Biological Process	GO:0008284	positive regulation of cell population proliferation	Nodal	IMP	MGI:MGI:2180793	Mouse	PMID:15004567
Biological Process	GO:0022409	positive regulation of cell-cell adhesion	NODAL	IMP		Human	PMID:21116837
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	NODAL	IDA		Human	PMID:15150278
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	NODAL	IMP		Human	PMID:21116837
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	NODAL	IDA		Human	PMID:21656830
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	NODAL	IMP		Human	PMID:21116837
Biological Process	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway	ndr1	IGI	ZFIN:ZDB-GENO-000731-1	Zfish	PMID:16873584
Biological Process	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	NODAL	IMP		Human	PMID:21741376
Biological Process	GO:0060391	positive regulation of SMAD protein signal transduction	NODAL	IMP		Human	PMID:21741376
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nodal	IDA		Mouse	MGI:MGI:5315339|PMID:17507406
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nodal	IGI	MGI:MGI:98658	Mouse	PMID:17568773
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nodal	IGI	MGI:MGI:1347465	Mouse	PMID:17568773
Biological Process	GO:0010575	positive regulation of vascular endothelial growth factor production	NODAL	IMP		Human	PMID:21116837
Biological Process	GO:0060215	primitive hemopoiesis	ndr1	IGI	ZFIN:ZDB-GENE-990630-14	Zfish	PMID:28687631
Biological Process	GO:0090009	primitive streak formation	Nodal	IGI	MGI:MGI:96086	Mouse	PMID:21445260
Biological Process	GO:0016485	protein processing	ndr1	IMP		Zfish	PMID:29140251
Biological Process	GO:0016485	protein processing	ndr2	IMP		Zfish	PMID:29140251
Biological Process	GO:0009306	protein secretion	ndr1	IMP		Zfish	PMID:29140251
Biological Process	GO:0009306	protein secretion	ndr2	IMP		Zfish	PMID:29140251
Biological Process	GO:2000223	regulation of BMP signaling pathway involved in heart jogging	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-1	Zfish	PMID:12702646
Biological Process	GO:2000223	regulation of BMP signaling pathway involved in heart jogging	spaw	IMP	ZFIN:ZDB-MRPHLNO-060112-2	Zfish	PMID:12702646
Biological Process	GO:2000223	regulation of BMP signaling pathway involved in heart jogging	ndr2	IMP	ZFIN:ZDB-GENO-980202-1194	Zfish	PMID:9334285
Biological Process	GO:0010470	regulation of gastrulation	Nodal	IGI	MGI:MGI:1194497	Mouse	PMID:20040491
Biological Process	GO:0010470	regulation of gastrulation	Nodal	IGI	MGI:MGI:1915299	Mouse	PMID:20040491
Biological Process	GO:0009966	regulation of signal transduction	Nodal	IDA		Mouse	PMID:17936261
Biological Process	GO:0060041	retina development in camera-type eye	ndr2	IMP	ZFIN:ZDB-GENO-050209-15	Zfish	PMID:12538521
Biological Process	GO:0031290	retinal ganglion cell axon guidance	ndr2	IMP	ZFIN:ZDB-GENO-980202-1194	Zfish	PMID:9007260
Biological Process	GO:0031290	retinal ganglion cell axon guidance	ndr2	IMP	ZFIN:ZDB-GENO-980202-871	Zfish	PMID:9007260
Biological Process	GO:0031290	retinal ganglion cell axon guidance	ndr2	IMP	ZFIN:ZDB-GENO-120314-27	Zfish	PMID:9007260
Biological Process	GO:0031290	retinal ganglion cell axon guidance	ndr2	IMP	ZFIN:ZDB-GENO-980202-828	Zfish	PMID:9007260
Biological Process	GO:0060395	SMAD protein signal transduction	Nodal	IDA		Mouse	PMID:9420335
Biological Process	GO:0035019	somatic stem cell population maintenance	Nodal	IGI	MGI:MGI:95518	Mouse	PMID:15505202
Biological Process	GO:0035019	somatic stem cell population maintenance	Nodal	IMP	MGI:MGI:2180793	Mouse	PMID:16678814
Biological Process	GO:0060061	Spemann organizer formation	ndr2	IMP	ZFIN:ZDB-GENO-100215-4	Zfish	PMID:10704853
Biological Process	GO:0060061	Spemann organizer formation	ndr1	IMP	ZFIN:ZDB-GENO-100215-2	Zfish	PMID:10704853
Biological Process	GO:0019827	stem cell population maintenance	Nodal	IGI	MGI:MGI:95518	Mouse	PMID:15505202
Biological Process	GO:0021537	telencephalon development	ndr2	IMP		Zfish	PMID:11239427
Biological Process	GO:0048729	tissue morphogenesis	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163
Biological Process	GO:0090010	transforming growth factor beta receptor signaling pathway involved in primitive streak formation	Nodal	IMP		Mouse	PMID:14511481
Biological Process	GO:0001829	trophectodermal cell differentiation	Nodal	IDA		Mouse	PMID:11456449
Biological Process	GO:0001831	trophectodermal cellular morphogenesis	Nodal	IMP	MGI:MGI:2158730	Mouse	PMID:11456449
Biological Process	GO:0001831	trophectodermal cellular morphogenesis	Nodal	IMP	MGI:MGI:1856970	Mouse	PMID:11456449
Biological Process	GO:0001944	vasculature development	Nodal	IMP	MGI:MGI:2158732	Mouse	PMID:11311163

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern