Comparative GO Graph (mouse, human, rat)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nol3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NOL3
- Mouse genes Nol3
- Rat genes Nol3
- Zfish genes
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nol3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	NOL3	IMP		Human	PMID:15509781
Molecular Function	GO:0089720	caspase binding	NOL3	IPI	UniProtKB:Q14790	Human	PMID:15509781
Molecular Function	GO:0089720	caspase binding	NOL3	IPI	UniProtKB:P42575	Human	PMID:9560245
Molecular Function	GO:0089720	caspase binding	NOL3	IPI	UniProtKB:Q14790	Human	PMID:9560245
Molecular Function	GO:0089720	caspase binding	Nol3	IPI	UniProtKB:Q9JHX4	Rat	PMID:12191471\|RGD:631884
Molecular Function	GO:0089720	caspase binding	Nol3	IPI	UniProtKB:P55215	Rat	PMID:16639714\|RGD:10047164
Molecular Function	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	NOL3	IDA		Human	PMID:9560245
Molecular Function	GO:0035877	death effector domain binding	Nol3	IPI	UniProtKB:O89110	Mouse	MGI:MGI:5613476\|PMID:15383280
Molecular Function	GO:0035877	death effector domain binding	Nol3	IPI	UniProtKB:Q61160	Rat	PMID:15383280\|RGD:10047289
Molecular Function	GO:0005123	death receptor binding	Nol3	IPI	UniProtKB:P19438	Mouse	MGI:MGI:5617337\|PMID:24440909
Molecular Function	GO:0042802	identical protein binding	NOL3	IPI	UniProtKB:O60936	Human	PMID:16189514
Molecular Function	GO:0019900	kinase binding	Nol3	IPI	UniProtKB:P68400	Rat	PMID:12191471\|RGD:631884
Molecular Function	GO:0019902	phosphatase binding	Nol3	IPI	UniProtKB:Q8K3W9	Rat	PMID:16639714\|RGD:10047164
Molecular Function	GO:0005515	protein binding	NOL3	IPI	UniProtKB:Q13242	Human	PMID:10196175
Molecular Function	GO:0005515	protein binding	NOL3	IPI	UniProtKB:Q63690	Human	PMID:15004034
Molecular Function	GO:0005515	protein binding	NOL3	IPI	UniProtKB:P04637	Human	PMID:18087040
Molecular Function	GO:0005515	protein binding	NOL3	IPI	UniProtKB:Q14790	Human	PMID:18245485
Molecular Function	GO:0005515	protein binding	NOL3	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	NOL3	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NOL3	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Nol3	IPI	UniProtKB:Q07813	Mouse	MGI:MGI:5613476\|PMID:15383280
Molecular Function	GO:0005515	protein binding	Nol3	IPI	UniProtKB:Q6PFR5	Mouse	MGI:MGI:3616383\|PMID:16249178
Molecular Function	GO:0005515	protein binding	Nol3	IPI	UniProtKB:Q9JMG6	Rat	PMID:10644725\|RGD:634398
Molecular Function	GO:0005515	protein binding	Nol3	IPI	UniProtKB:Q63690	Rat	PMID:16639714\|RGD:10047164
Molecular Function	GO:0005515	protein binding	Nol3	IPI	UniProtKB:O35147	Rat	PMID:17998337\|RGD:10047225
Molecular Function	GO:0005515	protein binding	Nol3	IPI	UniProtKB:Q80ZG6	Rat	PMID:17998337\|RGD:10047225
Molecular Function	GO:0005102	signaling receptor binding	Nol3	IPI	UniProtKB:P25446	Mouse	MGI:MGI:5613476\|PMID:15383280
Cellular Component	GO:0005737	cytoplasm	Nol3	IDA		Rat	PMID:10590251\|RGD:10047155
Cellular Component	GO:0005737	cytoplasm	Nol3	IDA		Rat	PMID:12191471\|RGD:631884
Cellular Component	GO:0005739	mitochondrion	Nol3	IDA		Mouse	PMID:14645204
Cellular Component	GO:0005739	mitochondrion	Nol3	IDA		Rat	PMID:10590251\|RGD:10047155
Cellular Component	GO:0005739	mitochondrion	Nol3	IDA		Rat	PMID:12191471\|RGD:631884
Cellular Component	GO:0005739	mitochondrion	Nol3	IDA		Rat	PMID:16639714\|RGD:10047164
Cellular Component	GO:0016528	sarcoplasm	Nol3	IDA		Mouse	PMID:14645204
Cellular Component	GO:0016529	sarcoplasmic reticulum	Nol3	IDA		Rat	PMID:23382383\|RGD:10047354
Biological Process	GO:0001974	blood vessel remodeling	Nol3	IMP		Mouse	MGI:MGI:5469572\|PMID:22082675
Biological Process	GO:0010659	cardiac muscle cell apoptotic process	Nol3	IMP		Mouse	MGI:MGI:3710289\|PMID:16505176
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Nol3	IEP		Rat	PMID:16157298\|RGD:152025207
Biological Process	GO:0071456	cellular response to hypoxia	Nol3	IDA		Rat	PMID:22082675\|RGD:10047303
Biological Process	GO:0097340	inhibition of cysteine-type endopeptidase activity	Nol3	IMP		Rat	PMID:16639714\|RGD:10047164
Biological Process	GO:0097340	inhibition of cysteine-type endopeptidase activity	Nol3	IDA		Rat	PMID:17292893\|RGD:10047212
Biological Process	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process	NOL3	IDA		Human	PMID:15509781
Biological Process	GO:0097193	intrinsic apoptotic signaling pathway	Nol3	IMP		Mouse	MGI:MGI:5573029\|PMID:24312627
Biological Process	GO:0006376	mRNA splice site selection	NOL3	IDA		Human	PMID:10196175
Biological Process	GO:0045445	myoblast differentiation	Nol3	IDA		Rat	PMID:17292893\|RGD:10047212
Biological Process	GO:0043066	negative regulation of apoptotic process	NOL3	IMP		Human	PMID:15509781
Biological Process	GO:0043066	negative regulation of apoptotic process	Nol3	IMP		Mouse	MGI:MGI:5469572\|PMID:22082675
Biological Process	GO:0043066	negative regulation of apoptotic process	Nol3	IDA		Rat	PMID:19001025\|RGD:8553292
Biological Process	GO:0043066	negative regulation of apoptotic process	Nol3	IMP		Rat	PMID:23382383\|RGD:10047354
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptotic process	Nol3	IMP		Mouse	MGI:MGI:3710289\|PMID:16505176
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	Nol3	IDA		Rat	PMID:19001025\|RGD:8553292
Biological Process	GO:0051481	negative regulation of cytosolic calcium ion concentration	Nol3	IMP		Rat	PMID:23382383\|RGD:10047354
Biological Process	GO:1903073	negative regulation of death-inducing signaling complex assembly	Nol3	IDA		Rat	PMID:12191471\|RGD:631884
Biological Process	GO:1903073	negative regulation of death-inducing signaling complex assembly	Nol3	IDA		Rat	PMID:15383280\|RGD:10047289
Biological Process	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	NOL3	IDA		Human	PMID:9560245
Biological Process	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Nol3	IMP		Rat	PMID:12191471\|RGD:631884
Biological Process	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	Nol3	IMP		Rat	PMID:15383280\|RGD:10047289
Biological Process	GO:1903206	negative regulation of hydrogen peroxide-induced cell death	Nol3	IMP		Rat	PMID:16639714\|RGD:10047164
Biological Process	GO:1903206	negative regulation of hydrogen peroxide-induced cell death	Nol3	IDA		Rat	PMID:17292893\|RGD:10047212
Biological Process	GO:1903298	negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway	Nol3	IDA		Rat	PMID:10590251\|RGD:10047155
Biological Process	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	Nol3	IMP		Rat	PMID:15383280\|RGD:10047289
Biological Process	GO:0051562	negative regulation of mitochondrial calcium ion concentration	Nol3	IDA		Rat	PMID:23382383\|RGD:10047354
Biological Process	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process	Nol3	IMP		Mouse	MGI:MGI:5573029\|PMID:24312627
Biological Process	GO:0014736	negative regulation of muscle atrophy	Nol3	IMP		Mouse	MGI:MGI:5573029\|PMID:24312627
Biological Process	GO:0060547	negative regulation of necrotic cell death	Nol3	IMP		Mouse	MGI:MGI:5617337\|PMID:24440909
Biological Process	GO:1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	NOL3	IDA		Human	PMID:15004034
Biological Process	GO:1903215	negative regulation of protein targeting to mitochondrion	Nol3	IDA		Rat	PMID:16639714\|RGD:10047164
Biological Process	GO:0090201	negative regulation of release of cytochrome c from mitochondria	NOL3	IDA		Human	PMID:15004034
Biological Process	GO:0090201	negative regulation of release of cytochrome c from mitochondria	Nol3	IDA		Rat	PMID:10590251\|RGD:10047155
Biological Process	GO:0010664	negative regulation of striated muscle cell apoptotic process	Nol3	IMP		Mouse	MGI:MGI:5573029\|PMID:24312627
Biological Process	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway	Nol3	IMP		Mouse	MGI:MGI:5617337\|PMID:24440909
Biological Process	GO:0051259	protein complex oligomerization	NOL3	IDA		Human	PMID:10196175
Biological Process	GO:0010468	regulation of gene expression	Nol3	IMP		Mouse	PMID:18782777
Biological Process	GO:1901222	regulation of NIK/NF-kappaB signaling	Nol3	IMP		Mouse	MGI:MGI:5617337\|PMID:24440909
Biological Process	GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	Nol3	IMP		Rat	PMID:23382383\|RGD:10047354
Biological Process	GO:0014808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	NOL3	IDA		Human	PMID:15509781
Biological Process	GO:0001666	response to hypoxia	Nol3	IMP		Mouse	PMID:18782777
Biological Process	GO:0001666	response to hypoxia	Nol3	IEP		Rat	PMID:12753927\|RGD:1299527
Biological Process	GO:0014876	response to injury involved in regulation of muscle adaptation	Nol3	IMP		Mouse	PMID:18782777
Biological Process	GO:0002931	response to ischemia	Nol3	IMP		Mouse	MGI:MGI:3710289\|PMID:16505176
Biological Process	GO:0048659	smooth muscle cell proliferation	Nol3	IMP		Rat	PMID:22082675\|RGD:10047303

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.