Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NOLC1
  • Mouse genes Nolc1
  • Rat genes Nolc1
  • Zfish genes nolc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nolc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0034512	box C/D RNA binding	Nolc1	IDA		Rat	PMID:10679015|RGD:633515
Molecular Function	GO:0034512	box C/D RNA binding	Nolc1	IDA		Rat	PMID:12446766|RGD:633420
Molecular Function	GO:0062064	box C/D snoRNP complex binding	Nolc1	IDA		Rat	PMID:10679015|RGD:633515
Molecular Function	GO:0034513	box H/ACA snoRNA binding	Nolc1	IDA		Rat	PMID:10679015|RGD:633515
Molecular Function	GO:0034513	box H/ACA snoRNA binding	Nolc1	IDA		Rat	PMID:12446766|RGD:633420
Molecular Function	GO:0062065	box H/ACA snoRNP complex binding	Nolc1	IDA		Rat	PMID:10679015|RGD:633515
Molecular Function	GO:0140678	molecular function inhibitor activity	NOLC1	EXP		Human	PMID:22906532
Molecular Function	GO:0008139	nuclear localization sequence binding	Nolc1	IDA		Rat	PMID:1623516|RGD:633419
Molecular Function	GO:0005515	protein binding	NOLC1	IPI	UniProtKB:P32121	Human	PMID:17620599
Molecular Function	GO:0005515	protein binding	NOLC1	IPI	UniProtKB:P49407	Human	PMID:17620599
Molecular Function	GO:0005515	protein binding	NOLC1	IPI	UniProtKB:P04591:PRO_0000038593	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	NOLC1	IPI	UniProtKB:Q8NFY9	Human	PMID:26399832
Molecular Function	GO:0005515	protein binding	Nolc1	IPI	UniProtKB:Q9QXI1	Mouse	PMID:11470819
Molecular Function	GO:0005515	protein binding	Nolc1	IPI	RGD:1563995|RGD:1305542	Rat	PMID:12446766|RGD:633420
Molecular Function	GO:0005515	protein binding	Nolc1	IPI	RGD:621780	Rat	PMID:16208318|RGD:4892131
Molecular Function	GO:0019904	protein domain specific binding	Nolc1	IPI	RGD:2327	Rat	PMID:9553145|RGD:2303817
Molecular Function	GO:0046982	protein heterodimerization activity	NOLC1	IPI	UniProtKB:Q13428	Human	PMID:26399832
Molecular Function	GO:0030674	protein-macromolecule adaptor activity	NOLC1	IDA		Human	PMID:26399832
Molecular Function	GO:0003723	RNA binding	NOLC1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	NOLC1	HDA		Human	PMID:22681889
Molecular Function	GO:0001093	TFIIB-class transcription factor binding	Nolc1	IDA		Rat	PMID:8972203|RGD:2303819
Cellular Component	GO:0031428	box C/D RNP complex	Nolc1	IDA		Rat	PMID:10679015|RGD:633515
Cellular Component	GO:0031429	box H/ACA snoRNP complex	Nolc1	IDA		Rat	PMID:10679015|RGD:633515
Cellular Component	GO:0015030	Cajal body	Nolc1	IDA		Mouse	PMID:11470819
Cellular Component	GO:0001650	fibrillar center	NOLC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	Nolc1	IDA		Mouse	PMID:11470819
Cellular Component	GO:0005730	nucleolus	Nolc1	IDA		Rat	PMID:10679015|RGD:633515
Cellular Component	GO:0005730	nucleolus	Nolc1	IDA		Rat	PMID:12446766|RGD:633420
Cellular Component	GO:0005654	nucleoplasm	Nolc1	IDA		Mouse	PMID:11424213
Cellular Component	GO:0005654	nucleoplasm	Nolc1	IDA		Rat	PMID:1623516|RGD:633419
Biological Process	GO:0033979	box H/ACA RNA metabolic process	Nolc1	IGI	SGD:S000001800	Rat	PMID:12700234|RGD:2303815
Biological Process	GO:1904888	cranial skeletal system development	nolc1	IMP	ZFIN:ZDB-MRPHLNO-161205-3	Zfish	PMID:30849304
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	nolc1	IMP	ZFIN:ZDB-MRPHLNO-120203-2,ZFIN:ZDB-MRPHLNO-120203-3	Zfish	PMID:22295061
Biological Process	GO:0014032	neural crest cell development	NOLC1	IMP		Human	PMID:26399832
Biological Process	GO:0014029	neural crest formation	NOLC1	IMP		Human	PMID:26399832
Biological Process	GO:0007000	nucleolus organization	Nolc1	IDA		Mouse	PMID:11424213
Biological Process	GO:0008284	positive regulation of cell population proliferation	Nolc1	IGI	SGD:S000001800	Rat	PMID:12700234|RGD:2303815
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Nolc1	IDA		Rat	PMID:8972203|RGD:2303819
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Nolc1	IDA		Rat	PMID:9553145|RGD:2303817
Biological Process	GO:0042306	regulation of protein import into nucleus	Nolc1	IDA		Rat	PMID:1623516|RGD:633419
Biological Process	GO:0006417	regulation of translation	NOLC1	IMP		Human	PMID:26399832
Biological Process	GO:0006970	response to osmotic stress	Nolc1	IEP		Rat	PMID:10386602|RGD:2303816

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern