Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NOP53
  • Mouse genes Nop53
  • Rat genes Nop53
  • Zfish genes nop53
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nop53

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008097	5S rRNA binding	NOP53	IDA		Human	PMID:24120868
Molecular Function	GO:0042802	identical protein binding	NOP53	IDA		Human	PMID:24735870
Molecular Function	GO:0002039	p53 binding	NOP53	IPI	UniProtKB:P04637	Human	PMID:22522597
Molecular Function	GO:0005515	protein binding	NOP53	IPI	UniProtKB:P60484	Human	PMID:15355975
Molecular Function	GO:0005515	protein binding	NOP53	IPI	UniProtKB:F5HGJ3	Human	PMID:20042497
Molecular Function	GO:0005515	protein binding	NOP53	IPI	UniProtKB:P35240	Human	PMID:21167305
Molecular Function	GO:0005515	protein binding	NOP53	IPI	UniProtKB:P62913	Human	PMID:24556985
Molecular Function	GO:0005515	protein binding	NOP53	IPI	UniProtKB:P06748	Human	PMID:25956029
Molecular Function	GO:0005515	protein binding	NOP53	IPI	UniProtKB:Q8N726	Human	PMID:27323397
Molecular Function	GO:0005515	protein binding	NOP53	IPI	UniProtKB:P17480	Human	PMID:27729611
Molecular Function	GO:0005515	protein binding	NOP53	IPI	UniProtKB:O95786	Human	PMID:27824081
Molecular Function	GO:0005515	protein binding	NOP53	IPI	UniProtKB:P62913	Human	PMID:27829214
Molecular Function	GO:0005515	protein binding	NOP53	IPI	UniProtKB:Q9H2G4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NOP53	IPI	UniProtKB:P26583	Human	PMID:31694235
Molecular Function	GO:0005515	protein binding	NOP53	IPI	UniProtKB:Q8NHQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NOP53	IPI	UniProtKB:Q9H2G4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NOP53	IPI	UniProtKB:P26583	Human	PMID:32867128
Molecular Function	GO:0005515	protein binding	Nop53	IPI	UniProtKB:Q9CXW4	Mouse	MGI:MGI:5897550|PMID:21804542
Molecular Function	GO:0003723	RNA binding	NOP53	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	NOP53	HDA		Human	PMID:22681889
Cellular Component	GO:0005829	cytosol	NOP53	IDA		Human	PMID:24923447
Cellular Component	GO:0001650	fibrillar center	NOP53	IDA		Human	PMID:27729611
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	NOP53	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	NOP53	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	NOP53	IDA		Human	PMID:20042497
Cellular Component	GO:0005730	nucleolus	NOP53	IDA		Human	PMID:22522597
Cellular Component	GO:0005730	nucleolus	NOP53	IDA		Human	PMID:24923447
Cellular Component	GO:0005730	nucleolus	NOP53	IDA		Human	PMID:25956029
Cellular Component	GO:0005730	nucleolus	NOP53	IDA		Human	PMID:27323397
Cellular Component	GO:0005730	nucleolus	NOP53	IDA		Human	PMID:27829214
Cellular Component	GO:0005730	nucleolus	Nop53	IDA		Mouse	MGI:MGI:5897550|PMID:21804542
Cellular Component	GO:0005654	nucleoplasm	NOP53	IDA		Human	PMID:22522597
Cellular Component	GO:0005654	nucleoplasm	NOP53	IDA		Human	PMID:24923447
Cellular Component	GO:0005654	nucleoplasm	NOP53	IDA		Human	PMID:27323397
Cellular Component	GO:0033553	rDNA heterochromatin	NOP53	IDA		Human	PMID:27729611
Biological Process	GO:0071456	cellular response to hypoxia	NOP53	IMP		Human	PMID:22522597
Biological Process	GO:0006974	DNA damage response	NOP53	IMP		Human	PMID:27829214
Biological Process	GO:0006281	DNA repair	NOP53	IMP		Human	PMID:21741933
Biological Process	GO:0007095	mitotic G2 DNA damage checkpoint signaling	NOP53	IMP		Human	PMID:21741933
Biological Process	GO:0014067	negative regulation of phosphatidylinositol 3-kinase signaling	NOP53	IMP		Human	PMID:16971513
Biological Process	GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	NOP53	IMP		Human	PMID:22522597
Biological Process	GO:0051898	negative regulation of protein kinase B signaling	NOP53	IMP		Human	PMID:27729611
Biological Process	GO:0031333	negative regulation of protein-containing complex assembly	NOP53	IMP		Human	PMID:25956029
Biological Process	GO:1901797	negative regulation of signal transduction by p53 class mediator	Nop53	IMP		Mouse	MGI:MGI:5897550|PMID:21804542
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NOP53	IMP		Human	PMID:25956029
Biological Process	GO:1901837	negative regulation of transcription of nucleolar large rRNA by RNA polymerase I	NOP53	IMP		Human	PMID:27729611
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	NOP53	IMP		Human	PMID:25818168
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	NOP53	IMP		Human	PMID:27323397
Biological Process	GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	Nop53	IMP		Mouse	MGI:MGI:5897550|PMID:21804542
Biological Process	GO:1903006	positive regulation of protein K63-linked deubiquitination	NOP53	IMP		Human	PMID:27824081
Biological Process	GO:1902570	protein localization to nucleolus	Nop53	IMP		Mouse	MGI:MGI:5897550|PMID:21804542
Biological Process	GO:1990173	protein localization to nucleoplasm	NOP53	IMP		Human	PMID:25818168
Biological Process	GO:1990173	protein localization to nucleoplasm	NOP53	IMP		Human	PMID:27323397
Biological Process	GO:0050821	protein stabilization	NOP53	IMP		Human	PMID:15355975
Biological Process	GO:1903715	regulation of aerobic respiration	NOP53	IMP		Human	PMID:24556985
Biological Process	GO:0042981	regulation of apoptotic process	NOP53	IMP		Human	PMID:21167305
Biological Process	GO:0051726	regulation of cell cycle	NOP53	IMP		Human	PMID:21167305
Biological Process	GO:0001932	regulation of protein phosphorylation	NOP53	IMP		Human	PMID:15355975
Biological Process	GO:0039535	regulation of RIG-I signaling pathway	NOP53	IMP		Human	PMID:27824081
Biological Process	GO:1901796	regulation of signal transduction by p53 class mediator	NOP53	IMP		Human	PMID:22522597
Biological Process	GO:1901796	regulation of signal transduction by p53 class mediator	NOP53	IMP		Human	PMID:24120868
Biological Process	GO:1901796	regulation of signal transduction by p53 class mediator	NOP53	IMP		Human	PMID:24556985
Biological Process	GO:1901796	regulation of signal transduction by p53 class mediator	NOP53	IMP		Human	PMID:27829214
Biological Process	GO:0000027	ribosomal large subunit assembly	NOP53	IMP		Human	PMID:24120868

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern