Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NOVA1
  • Mouse genes Nova1
  • Rat genes Nova1
  • Zfish genes nova1,nova2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nova1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003730	mRNA 3'-UTR binding	Nova1	IDA		Mouse	PMID:27378374
Molecular Function	GO:0003729	mRNA binding	Nova1	IDA		Mouse	MGI:MGI:6718240|PMID:14615540
Molecular Function	GO:0003729	mRNA binding	Nova1	IDA		Mouse	PMID:10719891
Molecular Function	GO:0005515	protein binding	NOVA1	IPI	UniProtKB:P18507	Human	PMID:27733149
Molecular Function	GO:0005515	protein binding	NOVA1	IPI	UniProtKB:P50406	Human	PMID:30853821
Molecular Function	GO:0005515	protein binding	Nova1	IPI	PR:Q91Z31	Mouse	PMID:10829067
Molecular Function	GO:0003723	RNA binding	NOVA1	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	Nova1	IDA		Mouse	MGI:MGI:6718242|PMID:8558240
Molecular Function	GO:0003723	RNA binding	Nova1	IDA		Mouse	PMID:27378374
Molecular Function	GO:1990825	sequence-specific mRNA binding	NOVA1	IDA		Human	PMID:10811881
Molecular Function	GO:1990825	sequence-specific mRNA binding	Nova1	IDA		Mouse	MGI:MGI:6717243|PMID:9154818
Molecular Function	GO:1990825	sequence-specific mRNA binding	Nova1	IDA		Mouse	MGI:MGI:6716952|PMID:17065982
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	NOVA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	NOVA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NOVA1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Nova1	IDA		Mouse	MGI:MGI:6718242|PMID:8558240
Biological Process	GO:0007411	axon guidance	nova1	IMP	ZFIN:ZDB-MRPHLNO-201007-1	Zfish	PMID:32197073
Biological Process	GO:0000398	mRNA splicing, via spliceosome	Nova1	IMP	MGI:MGI:2386947	Mouse	PMID:10719891
Biological Process	GO:0000398	mRNA splicing, via spliceosome	Nova1	IDA		Mouse	PMID:10719891
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	Nova1	IGI	UniProtKB:A0A1W2P872,UniProtKB:A0A1W2P872	Mouse	MGI:MGI:5810478|PMID:27635635
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Nova1	IMP		Mouse	MGI:MGI:5789071|PMID:27223325
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Nova1	IDA		Mouse	MGI:MGI:6716952|PMID:17065982
Biological Process	GO:0000381	regulation of alternative mRNA splicing, via spliceosome	Nova1	IMP		Mouse	MGI:MGI:6718240|PMID:14615540
Biological Process	GO:0050684	regulation of mRNA processing	Nova1	IMP		Rat	PMID:12124753|RGD:708602
Biological Process	GO:0051252	regulation of RNA metabolic process	Nova1	IGI	MGI:MGI:104296	Mouse	PMID:23359859
Biological Process	GO:0021510	spinal cord development	Nova1	IEP		Rat	PMID:12124753|RGD:708602

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern