Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NPAS2
  • Mouse genes Npas2
  • Rat genes Npas2
  • Zfish genes npas2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Npas2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	NPAS2	IDA		Human	PMID:11441146
Molecular Function	GO:0003677	DNA binding	Npas2	IDA		Mouse	MGI:MGI:5567897|PMID:23831463
Molecular Function	GO:0003690	double-stranded DNA binding	npas2	IDA		Zfish	PMID:12354100
Molecular Function	GO:0051879	Hsp90 protein binding	NPAS2	IDA		Human	PMID:9079689
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:Q09472	Human	PMID:14645221
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:Q92793	Human	PMID:14645221
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:Q92831	Human	PMID:14645221
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:Q9Y6Q9	Human	PMID:14645221
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:O00327-8	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:Q8WYA1-3	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:O00327-8	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:Q8WYA1-3	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:O00327-8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:O43639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:Q0VD86	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:Q5T6F2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:Q8WYA1-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:Q96IV0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:Q9NP55	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:Q14957	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NPAS2	IPI	UniProtKB:Q9Y649	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Npas2	IPI	UniProtKB:B2RWS6	Mouse	MGI:MGI:5559671|PMID:14645221
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	NPAS2	IDA		Human	PMID:28473536
Cellular Component	GO:0005829	cytosol	NPAS2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NPAS2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NPAS2	IDA		Human	PMID:14645221
Cellular Component	GO:0005667	transcription regulator complex	npas2	IPI	UniProtKB:Q8JIG1,UniProtKB:Q9I917	Zfish	PMID:12354100
Biological Process	GO:0032922	circadian regulation of gene expression	Npas2	IMP		Mouse	MGI:MGI:3794495|PMID:18316400
Biological Process	GO:0032922	circadian regulation of gene expression	Npas2	IMP		Mouse	MGI:MGI:5518489|PMID:24048828
Biological Process	GO:0032922	circadian regulation of gene expression	Npas2	IMP		Mouse	MGI:MGI:6282961|PMID:29163035
Biological Process	GO:0007623	circadian rhythm	Npas2	IEP		Mouse	MGI:MGI:5559671|PMID:14645221
Biological Process	GO:0007623	circadian rhythm	npas2	IGI	ZFIN:ZDB-MRPHLNO-050119-4,ZFIN:ZDB-MRPHLNO-050420-2,ZFIN:ZDB-MRPHLNO-050420-3,ZFIN:ZDB-MRPHLNO-050420-5	Zfish	PMID:15657039
Biological Process	GO:0042745	circadian sleep/wake cycle	Npas2	IMP	MGI:MGI:2180392	Mouse	PMID:12843397
Biological Process	GO:0006974	DNA damage response	NPAS2	IMP		Human	PMID:18819933
Biological Process	GO:0045475	locomotor rhythm	Npas2	IMP	MGI:MGI:2180392	Mouse	PMID:12843397
Biological Process	GO:0060548	negative regulation of cell death	NPAS2	IMP		Human	PMID:18819933
Biological Process	GO:0009648	photoperiodism	npas2	IEP		Zfish	PMID:12354100
Biological Process	GO:2000987	positive regulation of behavioral fear response	Npas2	IMP		Mouse	MGI:MGI:6282961|PMID:29163035
Biological Process	GO:0045739	positive regulation of DNA repair	NPAS2	IMP		Human	PMID:18819933
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NPAS2	IDA		Human	PMID:11441146
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NPAS2	IMP		Human	PMID:18819933
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Npas2	IMP		Mouse	MGI:MGI:6275703|PMID:25212631
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Npas2	IDA		Mouse	MGI:MGI:5518489|PMID:24048828
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Npas2	IDA		Mouse	MGI:MGI:3794495|PMID:18316400
Biological Process	GO:0042752	regulation of circadian rhythm	Npas2	IMP		Mouse	MGI:MGI:5518489|PMID:24048828
Biological Process	GO:0009416	response to light stimulus	npas2	IGI	ZFIN:ZDB-MRPHLNO-050119-4,ZFIN:ZDB-MRPHLNO-050420-2,ZFIN:ZDB-MRPHLNO-050420-3,ZFIN:ZDB-MRPHLNO-050420-5	Zfish	PMID:15657039
Biological Process	GO:0051775	response to redox state	NPAS2	IDA		Human	PMID:11441146
Biological Process	GO:0051775	response to redox state	Npas2	IDA		Mouse	MGI:MGI:5567897|PMID:23831463
Biological Process	GO:0009410	response to xenobiotic stimulus	Npas2	IMP		Mouse	MGI:MGI:6282961|PMID:29163035

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern