Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NPHP1
  • Mouse genes Nphp1
  • Rat genes Nphp1
  • Zfish genes nphp1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nphp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:O75161	Human	PMID:12244321
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:Q7Z494	Human	PMID:12872122
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:O75161	Human	PMID:15661758
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:Q13444	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:Q8N157	Human	PMID:18633336
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:P98161	Human	PMID:20856870
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:O75161	Human	PMID:21357692
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:Q14289	Human	PMID:21357692
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:O75161	Human	PMID:21565611
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:Q15051	Human	PMID:21565611
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:Q9Y283	Human	PMID:21565611
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:Q2M1P5	Human	PMID:21633164
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:Q8N157	Human	PMID:23532844
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:Q13444	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:O75161	Human	PMID:26638075
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:O75161	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	NPHP1	IPI	UniProtKB:Q9Y265	Human	PMID:29959317
Molecular Function	GO:0005515	protein binding	Nphp1	IPI	UniProtKB:Q9CZK6	Mouse	MGI:MGI:5621197|PMID:25671767
Molecular Function	GO:0005515	protein binding	Nphp1	IPI	UniProtKB:P59240	Mouse	MGI:MGI:5013991|PMID:21565611
Molecular Function	GO:0005515	protein binding	Nphp1	IPI	UniProtKB:Q61140	Mouse	MGI:MGI:1355157|PMID:10739664
Molecular Function	GO:0005515	protein binding	Nphp1	IPI	MGI:MGI:2144877	Mouse	PMID:29899041
Molecular Function	GO:0005515	protein binding	Nphp1	IPI	PR:Q80W68	Mouse	PMID:20233749
Molecular Function	GO:0005515	protein binding	Nphp1	IPI	PR:Q8BR86	Mouse	PMID:20233749
Molecular Function	GO:0005515	protein binding	Nphp1	IPI	PR:Q7TSU7	Mouse	PMID:20233749
Cellular Component	GO:0005911	cell-cell junction	NPHP1	IDA		Human	PMID:21565611
Cellular Component	GO:0097546	ciliary base	Nphp1	IDA		Mouse	PMID:20169535
Cellular Component	GO:0035869	ciliary transition zone	Nphp1	IDA		Mouse	MGI:MGI:5013991|PMID:21565611
Cellular Component	GO:0035869	ciliary transition zone	Nphp1	IDA		Mouse	PMID:24302887
Cellular Component	GO:0035869	ciliary transition zone	Nphp1	IDA		Mouse	PMID:20169535
Cellular Component	GO:0005929	cilium	Nphp1	IDA		Mouse	PMID:20172860
Cellular Component	GO:0005737	cytoplasm	Nphp1	IDA		Mouse	MGI:MGI:5013991|PMID:21565611
Cellular Component	GO:0031514	motile cilium	NPHP1	IDA		Human	PMID:16885411
Cellular Component	GO:0032391	photoreceptor connecting cilium	Nphp1	IDA		Mouse	MGI:MGI:4821072|PMID:16885411
Cellular Component	GO:0120206	photoreceptor distal connecting cilium	Nphp1	IDA		Mouse	PMID:29899041
Biological Process	GO:0030030	cell projection organization	Nphp1	IMP		Mouse	MGI:MGI:3839506|PMID:19208653
Biological Process	GO:0021782	glial cell development	nphp1	IMP	ZFIN:ZDB-CRISPR-191008-28,ZFIN:ZDB-CRISPR-191008-29	Zfish	PMID:30924555
Biological Process	GO:0035845	photoreceptor cell outer segment organization	Nphp1	IGI	UniProtKB:Q8K3E5	Mouse	MGI:MGI:4437526|PMID:20081859
Biological Process	GO:1903348	positive regulation of bicellular tight junction assembly	NPHP1	IMP		Human	PMID:19755384
Biological Process	GO:0048793	pronephros development	nphp1	IGI	ZFIN:ZDB-MRPHLNO-110908-2,ZFIN:ZDB-MRPHLNO-110908-3	Zfish	PMID:21596840
Biological Process	GO:0048793	pronephros development	nphp1	IMP	ZFIN:ZDB-MRPHLNO-110908-3	Zfish	PMID:21596840
Biological Process	GO:0008104	protein localization	Nphp1	IGI	UniProtKB:Q8K3E5	Mouse	MGI:MGI:4437526|PMID:20081859
Biological Process	GO:0060041	retina development in camera-type eye	Nphp1	IMP		Mouse	MGI:MGI:3839506|PMID:19208653
Biological Process	GO:0060041	retina development in camera-type eye	nphp1	IMP	ZFIN:ZDB-CRISPR-191008-28,ZFIN:ZDB-CRISPR-191008-29	Zfish	PMID:30924555
Biological Process	GO:0048515	spermatid differentiation	Nphp1	IMP		Mouse	MGI:MGI:3812271|PMID:18684731

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern