Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NPHP3
  • Mouse genes Nphp3
  • Rat genes Nphp3
  • Zfish genes nphp3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nphp3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NPHP3	IPI	UniProtKB:O15259	Human	PMID:12872122
Molecular Function	GO:0005515	protein binding	NPHP3	IPI	UniProtKB:Q9Y283	Human	PMID:18371931
Molecular Function	GO:0005515	protein binding	NPHP3	IPI	UniProtKB:A6NIH7	Human	PMID:22085962
Molecular Function	GO:0005515	protein binding	NPHP3	IPI	UniProtKB:Q13432	Human	PMID:22085962
Molecular Function	GO:0005515	protein binding	NPHP3	IPI	UniProtKB:Q9UPV0	Human	PMID:22863007
Molecular Function	GO:0005515	protein binding	NPHP3	IPI	UniProtKB:Q13432	Human	PMID:22960633
Molecular Function	GO:0005515	protein binding	NPHP3	IPI	UniProtKB:Q86SG6	Human	PMID:23418306
Molecular Function	GO:0005515	protein binding	NPHP3	IPI	UniProtKB:Q13432	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	NPHP3	IPI	UniProtKB:Q9Y265	Human	PMID:29959317
Molecular Function	GO:0005515	protein binding	Nphp3	IPI	PR:Q9Z2R6	Mouse	PMID:29395339
Molecular Function	GO:0005515	protein binding	Nphp3	IPI	PR:Q91ZR4	Mouse	PMID:29395339
Cellular Component	GO:0097546	ciliary base	Nphp3	IDA		Mouse	PMID:20169535
Cellular Component	GO:0097543	ciliary inversin compartment	Nphp3	IDA		Mouse	PMID:20169535
Cellular Component	GO:0097543	ciliary inversin compartment	Nphp3	IDA		Mouse	PMID:29395339
Cellular Component	GO:0005929	cilium	NPHP3	IDA		Human	PMID:20462968
Cellular Component	GO:0005929	cilium	NPHP3	IDA		Human	PMID:22085962
Biological Process	GO:0003283	atrial septum development	NPHP3	IMP		Human	PMID:18371931
Biological Process	GO:0060271	cilium assembly	Nphp3	IMP		Mouse	MGI:MGI:3807620|PMID:18371931
Biological Process	GO:0060271	cilium assembly	nphp3	IMP		Zfish	PMID:22085962|ZFIN:ZDB-PUB-120416-1
Biological Process	GO:0060271	cilium assembly	nphp3	IMP		Zfish	PMID:20462968|ZFIN:ZDB-PUB-100518-7
Biological Process	GO:0060026	convergent extension	nphp3	IMP	ZFIN:ZDB-MRPHLNO-100629-2	Zfish	PMID:20462968
Biological Process	GO:0060027	convergent extension involved in gastrulation	NPHP3	IGI	UniProtKB:Q6AZT7	Human	PMID:18371931
Biological Process	GO:0071908	determination of intestine left/right asymmetry	NPHP3	IMP		Human	PMID:20007846
Biological Process	GO:0007368	determination of left/right symmetry	NPHP3	IMP		Human	PMID:18371931
Biological Process	GO:0007368	determination of left/right symmetry	Nphp3	IMP		Mouse	MGI:MGI:3807620|PMID:18371931
Biological Process	GO:0071910	determination of liver left/right asymmetry	NPHP3	IMP		Human	PMID:20007846
Biological Process	GO:0035469	determination of pancreatic left/right asymmetry	NPHP3	IMP		Human	PMID:20007846
Biological Process	GO:0071909	determination of stomach left/right asymmetry	NPHP3	IMP		Human	PMID:18371931
Biological Process	GO:0007163	establishment or maintenance of cell polarity	Nphp3	IMP		Mouse	PMID:22832925
Biological Process	GO:0030198	extracellular matrix organization	Nphp3	IMP	MGI:MGI:1856987	Mouse	PMID:7539536
Biological Process	GO:0003146	heart jogging	nphp3	IMP	ZFIN:ZDB-MRPHLNO-100629-2	Zfish	PMID:20462968
Biological Process	GO:0001947	heart looping	NPHP3	IMP		Human	PMID:18371931
Biological Process	GO:0001947	heart looping	NPHP3	IMP		Human	PMID:20007846
Biological Process	GO:0001822	kidney development	NPHP3	IMP		Human	PMID:20007846
Biological Process	GO:0001822	kidney development	Nphp3	IMP	MGI:MGI:1856987	Mouse	PMID:24178445
Biological Process	GO:0060993	kidney morphogenesis	NPHP3	IMP		Human	PMID:18371931
Biological Process	GO:0060993	kidney morphogenesis	Nphp3	IMP		Mouse	MGI:MGI:3807620|PMID:18371931
Biological Process	GO:0060993	kidney morphogenesis	Nphp3	IMP	MGI:MGI:6159873	Mouse	PMID:29395339
Biological Process	GO:0070121	Kupffer's vesicle development	nphp3	IMP	ZFIN:ZDB-MRPHLNO-120424-7	Zfish	PMID:22085962
Biological Process	GO:0060972	left/right pattern formation	nphp3	IMP	ZFIN:ZDB-MRPHLNO-100629-2	Zfish	PMID:20462968
Biological Process	GO:0006629	lipid metabolic process	Nphp3	IMP	MGI:MGI:1856987	Mouse	PMID:1385849
Biological Process	GO:0030324	lung development	NPHP3	IMP		Human	PMID:20007846
Biological Process	GO:0048496	maintenance of animal organ identity	NPHP3	IMP		Human	PMID:12872122
Biological Process	GO:0048496	maintenance of animal organ identity	Nphp3	IMP		Mouse	MGI:MGI:3047096|PMID:12872122
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	NPHP3	IDA		Human	PMID:18371931
Biological Process	GO:1905515	non-motile cilium assembly	Nphp3	IMP		Mouse	PMID:22832925
Biological Process	GO:0045494	photoreceptor cell maintenance	NPHP3	IMP		Human	PMID:12872122
Biological Process	GO:0032092	positive regulation of protein binding	Nphp3	IMP	MGI:MGI:6159873	Mouse	PMID:29395339
Biological Process	GO:0048793	pronephros development	nphp3	IGI	ZFIN:ZDB-MRPHLNO-100629-4,ZFIN:ZDB-MRPHLNO-130910-9	Zfish	PMID:23793029
Biological Process	GO:0072189	ureter development	NPHP3	IMP		Human	PMID:18371931
Biological Process	GO:0007601	visual perception	nphp3	IMP	ZFIN:ZDB-MRPHLNO-120424-7	Zfish	PMID:22085962

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern