Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NPM2
  • Mouse genes Npm2
  • Rat genes Npm2
  • Zfish genes npm2a,npm2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Npm2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Npm2	IDA		Mouse	PMID:24105743
Molecular Function	GO:0019899	enzyme binding	Npm2	IDA		Rat	PMID:11481036|RGD:1600909
Molecular Function	GO:0042802	identical protein binding	Npm2	IPI	RGD:727816	Rat	PMID:8611572|RGD:1600911
Molecular Function	GO:0005515	protein binding	NPM2	IPI	UniProtKB:O75607	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NPM2	IPI	UniProtKB:P06748	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NPM2	IPI	UniProtKB:Q9H190	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NPM2	IPI	UniProtKB:Q9H8W4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NPM2	IPI	UniProtKB:O75607	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	NPM2	IPI	UniProtKB:O75607	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NPM2	IPI	UniProtKB:P06748	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NPM2	IPI	UniProtKB:Q9H190	Human	PMID:31515488
Cellular Component	GO:0000785	chromatin	NPM2	IDA		Human	PMID:12714744
Cellular Component	GO:0005634	nucleus	NPM2	IDA		Human	PMID:12714744
Cellular Component	GO:0005634	nucleus	Npm2	IDA		Mouse	PMID:12714744
Biological Process	GO:0001824	blastocyst development	NPM2	IMP		Human	PMID:12714744
Biological Process	GO:0006338	chromatin remodeling	NPM2	IDA		Human	PMID:12714744
Biological Process	GO:0006338	chromatin remodeling	Npm2	IMP	MGI:MGI:2182141	Mouse	PMID:12714744
Biological Process	GO:0007275	multicellular organism development	npm2b	IMP	ZFIN:ZDB-MRPHLNO-151103-1	Zfish	PMID:25009208
Biological Process	GO:0009994	oocyte differentiation	NPM2	IEP		Human	PMID:12714744
Biological Process	GO:0043085	positive regulation of catalytic activity	Npm2	IDA		Rat	PMID:11481036|RGD:1600909
Biological Process	GO:0051054	positive regulation of DNA metabolic process	Npm2	IDA		Rat	PMID:11481036|RGD:1600909
Biological Process	GO:0045740	positive regulation of DNA replication	Npm2	IDA		Rat	PMID:11481036|RGD:1600909
Biological Process	GO:0045836	positive regulation of meiotic nuclear division	NPM2	IMP		Human	PMID:12714744
Biological Process	GO:0007096	regulation of exit from mitosis	NPM2	IMP		Human	PMID:12714744
Biological Process	GO:0007338	single fertilization	NPM2	IMP		Human	PMID:12714744

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern