Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NPRL3
  • Mouse genes Nprl3
  • Rat genes Nprl3
  • Zfish genes nprl3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nprl3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005096	GTPase activator activity	NPRL3	IDA		Human	PMID:23723238
Molecular Function	GO:0005515	protein binding	NPRL3	IPI	UniProtKB:Q8WTW4	Human	PMID:19521502
Molecular Function	GO:0005515	protein binding	NPRL3	IPI	UniProtKB:Q5T011	Human	PMID:28199315
Molecular Function	GO:0005515	protein binding	NPRL3	IPI	UniProtKB:Q8WTW4	Human	PMID:28199315
Molecular Function	GO:0005515	protein binding	NPRL3	IPI	UniProtKB:Q8WTW4	Human	PMID:28514442
Cellular Component	GO:1990130	GATOR1 complex	NPRL3	IPI		Human	PMID:25263562
Cellular Component	GO:1990130	GATOR1 complex	NPRL3	IDA		Human	PMID:23723238
Cellular Component	GO:0005765	lysosomal membrane	NPRL3	IDA		Human	PMID:28199306
Biological Process	GO:0035909	aorta morphogenesis	Nprl3	IMP	MGI:MGI:5426855	Mouse	PMID:22538705
Biological Process	GO:0048738	cardiac muscle tissue development	Nprl3	IMP	MGI:MGI:5426855	Mouse	PMID:22538705
Biological Process	GO:0034198	cellular response to amino acid starvation	NPRL3	IMP		Human	PMID:23723238
Biological Process	GO:0032007	negative regulation of TOR signaling	NPRL3	IMP		Human	PMID:23723238
Biological Process	GO:0060021	roof of mouth development	Nprl3	IMP	MGI:MGI:5426855	Mouse	PMID:22538705
Biological Process	GO:0003281	ventricular septum development	Nprl3	IMP	MGI:MGI:5426855	Mouse	PMID:22538705

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern