Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nqo1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NQO1
- Mouse genes Nqo1
- Rat genes Nqo1
- Zfish genes nqo1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nqo1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	NQO1	IPI	UniProtKB:P15559	Human	PMID:25143260
Molecular Function	GO:0003955	NAD(P)H dehydrogenase (quinone) activity	Nqo1	IDA		Mouse	PMID:15386390
Molecular Function	GO:0003955	NAD(P)H dehydrogenase (quinone) activity	Nqo1	IDA		Mouse	PMID:1914521
Molecular Function	GO:0003955	NAD(P)H dehydrogenase (quinone) activity	Nqo1	IDA		Mouse	PMID:16190898
Molecular Function	GO:0003955	NAD(P)H dehydrogenase (quinone) activity	Nqo1	IDA		Rat	PMID:12603827\|RGD:727509
Molecular Function	GO:0050136	NADH dehydrogenase (quinone) activity	NQO1	IDA		Human	PMID:8999809
Molecular Function	GO:0050136	NADH dehydrogenase (quinone) activity	NQO1	IDA		Human	PMID:9271353
Molecular Function	GO:0050136	NADH dehydrogenase (quinone) activity	Nqo1	IDA		Mouse	MGI:MGI:85821\|PMID:8999809
Molecular Function	GO:0050136	NADH dehydrogenase (quinone) activity	Nqo1	IDA		Rat	PMID:8999809\|RGD:151356617
Molecular Function	GO:0005515	protein binding	NQO1	IPI	UniProtKB:P04637	Human	PMID:15687255
Molecular Function	GO:0005515	protein binding	NQO1	IPI	UniProtKB:Q9UK53	Human	PMID:18388957
Molecular Function	GO:0005515	protein binding	NQO1	IPI	UniProtKB:P50479	Human	PMID:21636573
Molecular Function	GO:0005515	protein binding	NQO1	IPI	UniProtKB:P07902	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Nqo1	IPI	UniProtKB:Q8R1G6	Mouse	PMID:29934320
Molecular Function	GO:0005515	protein binding	Nqo1	IPI	UniProtKB:Q9EST8	Mouse	PMID:29934320
Molecular Function	GO:0003723	RNA binding	NQO1	HDA		Human	PMID:22658674
Molecular Function	GO:0004784	superoxide dismutase activity	Nqo1	IMP		Rat	PMID:17901563\|RGD:5133248
Cellular Component	GO:0005737	cytoplasm	Nqo1	IDA		Mouse	PMID:29934320
Cellular Component	GO:0005737	cytoplasm	Nqo1	IDA		Rat	PMID:28322084\|RGD:13439751
Cellular Component	GO:0005737	cytoplasm	Nqo1	IDA		Rat	PMID:31819135\|RGD:25823186
Cellular Component	GO:0005829	cytosol	NQO1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	NQO1	IDA		Human	PMID:10945627
Cellular Component	GO:0005829	cytosol	Nqo1	IDA		Rat	PMID:14991562\|RGD:5133254
Cellular Component	GO:0005829	cytosol	Nqo1	IDA		Rat	PMID:30483575\|RGD:25823191
Cellular Component	GO:0030425	dendrite	Nqo1	IDA		Rat	PMID:28322084\|RGD:13439751
Cellular Component	GO:0043025	neuronal cell body	Nqo1	IDA		Rat	PMID:14991562\|RGD:5133254
Cellular Component	GO:0005634	nucleus	Nqo1	IDA		Mouse	PMID:29934320
Biological Process	GO:0007568	aging	Nqo1	IEP		Rat	PMID:21602469\|RGD:5133233
Biological Process	GO:0045454	cell redox homeostasis	NQO1	IEP		Human	PMID:21636573
Biological Process	GO:0070301	cellular response to hydrogen peroxide	Nqo1	IDA		Rat	PMID:28271112\|RGD:13440121
Biological Process	GO:0071248	cellular response to metal ion	Nqo1	IEP		Rat	PMID:28722058\|RGD:13439714
Biological Process	GO:0034599	cellular response to oxidative stress	NQO1	IDA		Human	PMID:15687255
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	nqo1	IDA		Zfish	PMID:18618001
Biological Process	GO:0001816	cytokine production	Nqo1	IMP	MGI:MGI:2388490	Mouse	PMID:29934320
Biological Process	GO:0045087	innate immune response	Nqo1	IMP	MGI:MGI:2388490	Mouse	PMID:29934320
Biological Process	GO:0006116	NADH oxidation	Nqo1	IDA		Rat	PMID:29389585\|RGD:25823193
Biological Process	GO:0070995	NADPH oxidation	Nqo1	IDA		Rat	PMID:29444417\|RGD:25823192
Biological Process	GO:0043066	negative regulation of apoptotic process	Nqo1	IDA		Rat	PMID:22227174\|RGD:10769366
Biological Process	GO:0043086	negative regulation of catalytic activity	Nqo1	IDA		Mouse	PMID:10903442
Biological Process	GO:0042177	negative regulation of protein catabolic process	NQO1	IDA		Human	PMID:15687255
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Nqo1	IMP		Rat	PMID:12603827\|RGD:727509
Biological Process	GO:0030163	protein catabolic process	Nqo1	IDA		Mouse	PMID:29934320
Biological Process	GO:0000209	protein polyubiquitination	Nqo1	IDA		Mouse	PMID:29934320
Biological Process	GO:0019430	removal of superoxide radicals	NQO1	IDA		Human	PMID:15102952
Biological Process	GO:0043279	response to alkaloid	Nqo1	IEP		Rat	PMID:31432116\|RGD:25823187
Biological Process	GO:0014075	response to amine	Nqo1	IDA		Rat	PMID:29444417\|RGD:25823192
Biological Process	GO:0009743	response to carbohydrate	Nqo1	IEP		Rat	PMID:31933629\|RGD:25823189
Biological Process	GO:0051602	response to electrical stimulus	Nqo1	IEP		Rat	PMID:28887183\|RGD:13434915
Biological Process	GO:0032355	response to estradiol	Nqo1	IEP		Rat	PMID:14672740\|RGD:5133258
Biological Process	GO:0045471	response to ethanol	Nqo1	IEP		Rat	PMID:20833713\|RGD:5133237
Biological Process	GO:1905395	response to flavonoid	Nqo1	IEP		Rat	PMID:31399183\|RGD:25823190
Biological Process	GO:0009725	response to hormone	Nqo1	IEP		Rat	PMID:30483575\|RGD:25823191
Biological Process	GO:1904880	response to hydrogen sulfide	Nqo1	IEP		Rat	PMID:29054567\|RGD:13442475
Biological Process	GO:0002931	response to ischemia	Nqo1	IEP		Rat	PMID:31399183\|RGD:25823190
Biological Process	GO:1904844	response to L-glutamine	Nqo1	IDA		Rat	PMID:30967905\|RGD:25823188
Biological Process	GO:0032496	response to lipopolysaccharide	Nqo1	IMP	MGI:MGI:2388490	Mouse	PMID:29934320
Biological Process	GO:1901698	response to nitrogen compound	Nqo1	IEP		Rat	PMID:27867096\|RGD:13442478
Biological Process	GO:0007584	response to nutrient	Nqo1	IEP		Rat	PMID:21092375\|RGD:5133236
Biological Process	GO:0014070	response to organic cyclic compound	Nqo1	IEP		Rat	PMID:21549141\|RGD:5133234
Biological Process	GO:0014070	response to organic cyclic compound	Nqo1	IEP		Rat	PMID:29307993\|RGD:25823195
Biological Process	GO:0014070	response to organic cyclic compound	Nqo1	IEP		Rat	PMID:30172374\|RGD:25823194
Biological Process	GO:0014070	response to organic cyclic compound	Nqo1	IEP		Rat	PMID:31889292\|RGD:21201308
Biological Process	GO:0010033	response to organic substance	Nqo1	IEP		Rat	PMID:29389585\|RGD:25823193
Biological Process	GO:0006979	response to oxidative stress	NQO1	IEP		Human	PMID:21636573
Biological Process	GO:0006979	response to oxidative stress	Nqo1	IMP	MGI:MGI:2388490	Mouse	PMID:15386390
Biological Process	GO:0006979	response to oxidative stress	Nqo1	IEP		Rat	PMID:12011483\|RGD:727372
Biological Process	GO:0033574	response to testosterone	Nqo1	IEP		Rat	PMID:31819135\|RGD:25823186
Biological Process	GO:1904772	response to tetrachloromethane	Nqo1	IEP		Rat	PMID:30483575\|RGD:25823191
Biological Process	GO:1904772	response to tetrachloromethane	Nqo1	IEP		Rat	PMID:31432116\|RGD:25823187
Biological Process	GO:0009410	response to xenobiotic stimulus	Nqo1	IEP		Rat	PMID:29091898\|RGD:15090820
Biological Process	GO:0009410	response to xenobiotic stimulus	Nqo1	IDA		Rat	PMID:30967905\|RGD:25823188
Biological Process	GO:0009410	response to xenobiotic stimulus	Nqo1	IEP		Rat	PMID:31889292\|RGD:21201308
Biological Process	GO:0006801	superoxide metabolic process	Nqo1	IMP		Rat	PMID:17901563\|RGD:5133248
Biological Process	GO:0006743	ubiquinone metabolic process	NQO1	IDA		Human	PMID:9271353
Biological Process	GO:0042360	vitamin E metabolic process	NQO1	IDA		Human	PMID:9271353
Biological Process	GO:0042373	vitamin K metabolic process	NQO1	IDA		Human	PMID:8999809
Biological Process	GO:0042373	vitamin K metabolic process	Nqo1	IDA		Mouse	MGI:MGI:85821\|PMID:8999809
Biological Process	GO:0042373	vitamin K metabolic process	Nqo1	IDA		Rat	PMID:8999809\|RGD:151356617

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/09/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.