Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NQO2
  • Mouse genes Nqo2
  • Rat genes Nqo2
  • Zfish genes nqo1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nqo2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031404	chloride ion binding	NQO2	IDA		Human	PMID:18254726
Molecular Function	GO:0001512	dihydronicotinamide riboside quinone reductase activity	NQO2	IDA		Human	PMID:18254726
Molecular Function	GO:0009055	electron transfer activity	NQO2	IDA		Human	PMID:10945627
Molecular Function	GO:0009055	electron transfer activity	NQO2	IDA		Human	PMID:18254726
Molecular Function	GO:0071949	FAD binding	NQO2	IDA		Human	PMID:18254726
Molecular Function	GO:1904408	melatonin binding	NQO2	IDA		Human	PMID:18254726
Molecular Function	GO:0016491	oxidoreductase activity	NQO2	IDA		Human	PMID:10945627
Molecular Function	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors	NQO2	IDA		Human	PMID:10945627
Molecular Function	GO:0005515	protein binding	NQO2	IPI	UniProtKB:Q9H8Y8	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	NQO2	IPI	UniProtKB:Q8IWL3	Human	PMID:24606901
Molecular Function	GO:0005515	protein binding	NQO2	IPI	UniProtKB:A1L1C6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NQO2	IPI	UniProtKB:Q9H8Y8	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	NQO2	IPI	UniProtKB:A1L1C6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NQO2	IPI	UniProtKB:Q5JVL4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NQO2	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NQO2	IPI	UniProtKB:Q9H8Y8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NQO2	IPI	UniProtKB:Q9NZD8	Human	PMID:32296183
Molecular Function	GO:0042803	protein homodimerization activity	NQO2	IPI	UniProtKB:P16083	Human	PMID:18254726
Molecular Function	GO:1905594	resveratrol binding	NQO2	IDA		Human	PMID:18254726
Molecular Function	GO:0008270	zinc ion binding	NQO2	IDA		Human	PMID:18254726
Cellular Component	GO:0005829	cytosol	NQO2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	NQO2	IDA		Human	PMID:10945627
Cellular Component	GO:0070062	extracellular exosome	NQO2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	NQO2	HDA		Human	PMID:23533145
Cellular Component	GO:0005654	nucleoplasm	NQO2	IDA		Human	GO_REF:0000052
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	nqo1	IDA		Zfish	PMID:18618001
Biological Process	GO:0007613	memory	Nqo2	IEP		Rat	PMID:17512093|RGD:2299897
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Nqo2	IMP		Rat	PMID:23554738|RGD:11073697
Biological Process	GO:0043525	positive regulation of neuron apoptotic process	Nqo2	IMP		Rat	PMID:20861374|RGD:11073700
Biological Process	GO:2000379	positive regulation of reactive oxygen species metabolic process	Nqo2	IMP		Rat	PMID:23554738|RGD:11073697
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	Nqo2	IMP		Rat	PMID:22508052|RGD:11073699
Biological Process	GO:1901662	quinone catabolic process	NQO2	IDA		Human	PMID:18254726

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern