Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nr0b1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NR0B1
- Mouse genes Nr0b1
- Rat genes Nr0b1
- Zfish genes nr0b1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nr0b1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032448	DNA hairpin binding	NR0B1	IDA		Human	PMID:9384387
Molecular Function	GO:0003690	double-stranded DNA binding	Nr0b1	IMP		Rat	PMID:12697699\|RGD:1624302
Molecular Function	GO:0016922	nuclear receptor binding	NR0B1	IPI	UniProtKB:P10275	Human	PMID:11875111
Molecular Function	GO:0016922	nuclear receptor binding	NR0B1	IPI	UniProtKB:P15207	Human	PMID:11875111
Molecular Function	GO:0005515	protein binding	NR0B1	IPI	UniProtKB:P06401-1	Human	PMID:12771131
Molecular Function	GO:0005515	protein binding	NR0B1	IPI	UniProtKB:P03372	Human	PMID:16709599
Molecular Function	GO:0005515	protein binding	NR0B1	IPI	UniProtKB:Q13285	Human	PMID:16709599
Molecular Function	GO:0005515	protein binding	NR0B1	IPI	UniProtKB:P35398	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	NR0B1	IPI	UniProtKB:P62508	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NR0B1	IPI	UniProtKB:Q13285	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NR0B1	IPI	UniProtKB:Q13285	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	NR0B1	IPI	UniProtKB:P62508-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR0B1	IPI	UniProtKB:Q13285	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR0B1	IPI	UniProtKB:Q96G04	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Nr0b1	IPI	UniProtKB:P20263\|UniProtKB:P70414\|UniProtKB:Q6PR54	Mouse	MGI:MGI:4399017\|PMID:17093407
Molecular Function	GO:0005515	protein binding	Nr0b1	IPI	UniProtKB:P20263\|UniProtKB:Q61539\|UniProtKB:Q6PR54	Mouse	MGI:MGI:5320277\|PMID:20362541
Molecular Function	GO:0005515	protein binding	Nr0b1	IPI	UniProtKB:Q61539	Mouse	MGI:MGI:5887187\|PMID:26206133
Molecular Function	GO:0005515	protein binding	Nr0b1	IPI	UniProtKB:Q80Z64	Mouse	MGI:MGI:5532893\|PMID:23892456
Molecular Function	GO:0005515	protein binding	Nr0b1	IPI	UniProtKB:Q80Z64	Mouse	MGI:MGI:4399017\|PMID:17093407
Molecular Function	GO:0005515	protein binding	Nr0b1	IPI	UniProtKB:P20263	Mouse	MGI:MGI:5529430\|PMID:23508100
Molecular Function	GO:0005515	protein binding	Nr0b1	IPI	UniProtKB:O09000	Mouse	MGI:MGI:5824766\|PMID:27601327
Molecular Function	GO:0005515	protein binding	Nr0b1	IPI	PR:P12813	Mouse	PMID:15155786
Molecular Function	GO:0019904	protein domain specific binding	NR0B1	IPI	UniProtKB:P10828	Human	PMID:15100213
Molecular Function	GO:0042803	protein homodimerization activity	NR0B1	IPI	UniProtKB:P51843	Human	PMID:16709599
Molecular Function	GO:0003723	RNA binding	NR0B1	IDA		Human	PMID:10848616
Molecular Function	GO:0003723	RNA binding	Nr0b1	IDA		Mouse	MGI:MGI:3694160\|PMID:10848616
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	NR0B1	IPI	UniProtKB:P22449	Human	PMID:19651776
Molecular Function	GO:0043565	sequence-specific DNA binding	Nr0b1	IMP		Rat	PMID:12697699\|RGD:1624302
Molecular Function	GO:0003714	transcription corepressor activity	NR0B1	IMP		Human	PMID:19651776
Molecular Function	GO:0003714	transcription corepressor activity	Nr0b1	IGI	MGI:MGI:1352454	Mouse	PMID:15155786
Molecular Function	GO:0008134	transcription factor binding	Nr0b1	IPI	UniProtKB:Q61539	Mouse	MGI:MGI:5824766\|PMID:27601327
Molecular Function	GO:0008134	transcription factor binding	Nr0b1	IPI	UniProtKB:Q61539	Mouse	MGI:MGI:5529430\|PMID:23508100
Cellular Component	GO:0034451	centriolar satellite	NR0B1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	NR0B1	IDA		Human	PMID:16709599
Cellular Component	GO:0005737	cytoplasm	Nr0b1	IDA		Mouse	PMID:16466956
Cellular Component	GO:0005737	cytoplasm	Nr0b1	IDA		Mouse	PMID:12610109
Cellular Component	GO:0005737	cytoplasm	Nr0b1	IDA		Mouse	PMID:14678822
Cellular Component	GO:0005737	cytoplasm	Nr0b1	IDA		Rat	PMID:8754790\|RGD:1601047
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	NR0B1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	NR0B1	IDA		Human	PMID:10848616
Cellular Component	GO:0016607	nuclear speck	NR0B1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NR0B1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NR0B1	IDA		Human	PMID:10848616
Cellular Component	GO:0005634	nucleus	NR0B1	IDA		Human	PMID:16709599
Cellular Component	GO:0005634	nucleus	NR0B1	IDA		Human	PMID:19651776
Cellular Component	GO:0005634	nucleus	NR0B1	IDA		Human	PMID:7990953
Cellular Component	GO:0005634	nucleus	Nr0b1	IDA		Mouse	MGI:MGI:3694160\|PMID:10848616
Cellular Component	GO:0005634	nucleus	Nr0b1	IDA		Mouse	PMID:19796622
Cellular Component	GO:0005634	nucleus	Nr0b1	IDA		Rat	PMID:12697699\|RGD:1624302
Cellular Component	GO:0042788	polysomal ribosome	NR0B1	IDA		Human	PMID:10848616
Cellular Component	GO:0042788	polysomal ribosome	Nr0b1	IDA		Mouse	MGI:MGI:3694160\|PMID:10848616
Biological Process	GO:0030325	adrenal gland development	NR0B1	IMP		Human	PMID:7990953
Biological Process	GO:0030325	adrenal gland development	Nr0b1	IGI	MGI:MGI:1346833	Mouse	PMID:11796523
Biological Process	GO:0035987	endodermal cell differentiation	Nr0b1	IMP		Mouse	PMID:16466956
Biological Process	GO:0008406	gonad development	NR0B1	IMP		Human	PMID:7990953
Biological Process	GO:0033327	Leydig cell differentiation	Nr0b1	IMP	MGI:MGI:2159321	Mouse	PMID:11564714
Biological Process	GO:0033327	Leydig cell differentiation	Nr0b1	IGI	MGI:MGI:1346833	Mouse	PMID:15829514
Biological Process	GO:0008584	male gonad development	NR0B1	IMP		Human	PMID:7990958
Biological Process	GO:0008584	male gonad development	Nr0b1	IMP	MGI:MGI:2159321	Mouse	PMID:12679814
Biological Process	GO:0030238	male sex determination	Nr0b1	IMP	MGI:MGI:2159321	Mouse	PMID:15944188
Biological Process	GO:0030238	male sex determination	Nr0b1	IGI	MGI:MGI:98660	Mouse	PMID:15944188
Biological Process	GO:0030238	male sex determination	Nr0b1	IMP	MGI:MGI:2159321	Mouse	PMID:12679814
Biological Process	GO:0050891	multicellular organismal-level water homeostasis	nr0b1	IMP	ZFIN:ZDB-MRPHLNO-070130-4	Zfish	PMID:16840536
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	NR0B1	IMP		Human	PMID:19651776
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	Nr0b1	IMP		Rat	PMID:12697699\|RGD:1624302
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	NR0B1	IMP		Human	PMID:19651776
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	NR0B1	IDA		Human	PMID:7990953
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	NR0B1	IDA		Human	PMID:9384387
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nr0b1	IDA		Mouse	MGI:MGI:5529430\|PMID:23508100
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nr0b1	IDA		Mouse	MGI:MGI:5824766\|PMID:27601327
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nr0b1	IDA		Mouse	PMID:15062575
Biological Process	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway	NR0B1	IDA		Human	PMID:11875111
Biological Process	GO:2000019	negative regulation of male gonad development	nr0b1	IMP	ZFIN:ZDB-GENO-170710-7	Zfish	PMID:27267667
Biological Process	GO:0010894	negative regulation of steroid biosynthetic process	NR0B1	IDA		Human	PMID:9384387
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr0b1	IGI	MGI:MGI:1352454	Mouse	PMID:15155786
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr0b1	IMP		Mouse	PMID:15155786
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr0b1	IMP		Rat	PMID:12697699\|RGD:1624302
Biological Process	GO:0008104	protein localization	NR0B1	IDA		Human	PMID:11875111
Biological Process	GO:0080021	response to benzoic acid	Nr0b1	IEP		Rat	PMID:30476341\|RGD:151893502
Biological Process	GO:0035902	response to immobilization stress	Nr0b1	IMP	MGI:MGI:2159321	Mouse	PMID:11796523
Biological Process	GO:0010033	response to organic substance	Nr0b1	IEP		Rat	PMID:16809437\|RGD:1601046
Biological Process	GO:0043434	response to peptide hormone	Nr0b1	IEP		Rat	PMID:15358680\|RGD:1357210
Biological Process	GO:0032526	response to retinoic acid	Nr0b1	HEP		Rat	PMID:30329139\|RGD:151893506
Biological Process	GO:0032526	response to retinoic acid	Nr0b1	IEP		Rat	PMID:30476341\|RGD:151893502
Biological Process	GO:0060008	Sertoli cell differentiation	Nr0b1	IMP	MGI:MGI:2159321	Mouse	PMID:11564714
Biological Process	GO:0060008	Sertoli cell differentiation	Nr0b1	IGI	MGI:MGI:1346833	Mouse	PMID:15829514
Biological Process	GO:0007530	sex determination	Nr0b1	IGI	MGI:MGI:98660	Mouse	PMID:9486644
Biological Process	GO:0007283	spermatogenesis	Nr0b1	IMP	MGI:MGI:2159321	Mouse	PMID:9843206
Biological Process	GO:0007283	spermatogenesis	Nr0b1	IMP	MGI:MGI:2159321	Mouse	PMID:11356697
Biological Process	GO:0007283	spermatogenesis	Nr0b1	IEP		Rat	PMID:8961266\|RGD:1601048

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 08/21/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.