Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NR0B2
  • Mouse genes Nr0b2
  • Rat genes Nr0b2
  • Zfish genes nr0b2a,nr0b2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nr0b2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042974	nuclear retinoic acid receptor binding	Nr0b2	IPI	RGD:733999	Rat	PMID:9003453|RGD:633448
Molecular Function	GO:0046965	nuclear retinoid X receptor binding	Nr0b2	IPI	RGD:11250	Rat	PMID:9003453|RGD:633448
Molecular Function	GO:0046966	nuclear thyroid hormone receptor binding	Nr0b2	IPI	RGD:3858	Rat	PMID:9003453|RGD:633448
Molecular Function	GO:0042975	peroxisome proliferator activated receptor binding	Nr0b2	IPI	RGD:732638	Rat	PMID:9003453|RGD:633448
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:Q02363	Human	PMID:14752053
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:Q13562	Human	PMID:14752053
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:Q96RI1	Human	PMID:15317749
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:P03372	Human	PMID:16709599
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:O15379	Human	PMID:17895379
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:Q13547	Human	PMID:17895379
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:Q96EB6	Human	PMID:20375098
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:O00482-1	Human	PMID:22504882
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:P04637	Human	PMID:22575647
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:Q00987	Human	PMID:22575647
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:O00571	Human	PMID:28128295
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:P62508-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:Q96AQ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:Q9Y4H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:P50570-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR0B2	IPI	UniProtKB:P54252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Nr0b2	IPI	UniProtKB:P70196|UniProtKB:Q04207	Mouse	MGI:MGI:5086034|PMID:21725320
Molecular Function	GO:0005515	protein binding	Nr0b2	IPI	UniProtKB:Q923E4	Mouse	MGI:MGI:5014028|PMID:20375098
Molecular Function	GO:0005515	protein binding	Nr0b2	IPI	UniProtKB:P51450|UniProtKB:Q3UV55	Mouse	MGI:MGI:6275703|PMID:25212631
Molecular Function	GO:0019904	protein domain specific binding	NR0B2	IPI	UniProtKB:P51843-1	Human	PMID:17686645
Molecular Function	GO:0042803	protein homodimerization activity	NR0B2	IPI	UniProtKB:Q15466	Human	PMID:16709599
Molecular Function	GO:0044877	protein-containing complex binding	Nr0b2	IDA		Rat	PMID:10648597|RGD:2311608
Molecular Function	GO:0003714	transcription corepressor activity	NR0B2	IDA		Human	PMID:14752053
Molecular Function	GO:0140416	transcription regulator inhibitor activity	NR0B2	IDA		Human	PMID:27471003
Cellular Component	GO:0000785	chromatin	NR0B2	IDA		Human	PMID:27471003
Cellular Component	GO:0005737	cytoplasm	NR0B2	IDA		Human	PMID:14752053
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	NR0B2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NR0B2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NR0B2	IDA		Human	PMID:14752053
Cellular Component	GO:0005634	nucleus	NR0B2	IDA		Human	PMID:16709599
Cellular Component	GO:0005634	nucleus	NR0B2	IDA		Human	PMID:28797635
Cellular Component	GO:0032991	protein-containing complex	Nr0b2	IDA		Rat	PMID:10648597|RGD:2311608
Cellular Component	GO:0032991	protein-containing complex	Nr0b2	IDA		Rat	PMID:15860571|RGD:1600916
Biological Process	GO:0031100	animal organ regeneration	Nr0b2	IEP		Rat	PMID:15904869|RGD:2311607
Biological Process	GO:0015721	bile acid and bile salt transport	Nr0b2	IEP		Rat	PMID:27939985|RGD:15036816
Biological Process	GO:0032922	circadian regulation of gene expression	Nr0b2	IMP		Mouse	MGI:MGI:6282985|PMID:30555544
Biological Process	GO:0032922	circadian regulation of gene expression	Nr0b2	IMP		Mouse	MGI:MGI:6275703|PMID:25212631
Biological Process	GO:0007623	circadian rhythm	NR0B2	IDA		Human	PMID:28797635
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	NR0B2	IDA		Human	PMID:14752053
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nr0b2	IMP		Mouse	MGI:MGI:6275703|PMID:25212631
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nr0b2	IMP		Rat	PMID:15860571|RGD:1600916
Biological Process	GO:0010629	negative regulation of gene expression	NR0B2	IMP		Human	PMID:19085950
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr0b2	IMP		Rat	PMID:15860571|RGD:1600916
Biological Process	GO:0007219	Notch signaling pathway	Nr0b2	IDA		Mouse	PMID:25446530
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NR0B2	IDA		Human	PMID:27471003
Biological Process	GO:0010628	positive regulation of gene expression	NR0B2	IMP		Human	PMID:19085950
Biological Process	GO:0032024	positive regulation of insulin secretion	Nr0b2	IMP		Rat	PMID:17259388|RGD:2311606
Biological Process	GO:0045471	response to ethanol	Nr0b2	IEP		Rat	PMID:27939985|RGD:15036816
Biological Process	GO:0009749	response to glucose	Nr0b2	IMP		Rat	PMID:17259388|RGD:2311606
Biological Process	GO:0014070	response to organic cyclic compound	Nr0b2	IEP		Rat	PMID:27939985|RGD:15036816

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern