Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NR1D2
  • Mouse genes Nr1d2
  • Rat genes Nr1d2
  • Zfish genes nr1d2a,nr1d2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nr1d2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Nr1d2	IDA		Mouse	MGI:MGI:5526936|PMID:19682428
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	Nr1d2	IDA		Mouse	MGI:MGI:5526909|PMID:23221024
Molecular Function	GO:0003677	DNA binding	Nr1d2	IDA		Mouse	PMID:7838156
Molecular Function	GO:0003677	DNA binding	Nr1d2	IDA		Mouse	PMID:7838158
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Nr1d2	IDA		Mouse	PMID:7838156
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Nr1d2	IDA		Mouse	PMID:7838158
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Nr1d2	IDA		Mouse	MGI:MGI:5905554|PMID:11058961
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:O43257	Human	PMID:17892483
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:Q13547	Human	PMID:17996965
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:Q92993	Human	PMID:17996965
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:Q96LA8	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:O08785	Human	PMID:23555304
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:O43255	Human	PMID:26392558
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:G5E9A7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:I6L9F6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:O15354	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:P06396	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:P28799-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:Q86WV8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:Q9UMX0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NR1D2	IPI	UniProtKB:Q9Y649	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Nr1d2	IPI	UniProtKB:Q9HCD5	Mouse	MGI:MGI:5315374|PMID:11113208
Molecular Function	GO:0005515	protein binding	Nr1d2	IPI	PR:P23611	Mouse	PMID:25331958
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NR1D2	IDA		Human	PMID:17892483
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NR1D2	IDA		Human	PMID:17996965
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nr1d2	IDA		Mouse	MGI:MGI:5905554|PMID:11058961
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	NR1D2	IDA		Human	PMID:28473536
Cellular Component	GO:0005737	cytoplasm	Nr1d2	IDA		Mouse	MGI:MGI:6294205|PMID:29508494
Cellular Component	GO:0005654	nucleoplasm	NR1D2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NR1D2	IDA		Human	PMID:17892483
Cellular Component	GO:0005634	nucleus	NR1D2	IDA		Human	PMID:17996965
Cellular Component	GO:0005634	nucleus	Nr1d2	IDA		Mouse	MGI:MGI:6294205|PMID:29508494
Biological Process	GO:0048512	circadian behavior	Nr1d2	IMP		Mouse	MGI:MGI:6157418|PMID:29723273
Biological Process	GO:0032922	circadian regulation of gene expression	nr1d2a	IDA		Zfish	PMID:24423866
Biological Process	GO:0097009	energy homeostasis	Nr1d2	IMP		Mouse	MGI:MGI:5526938|PMID:15623503
Biological Process	GO:0055088	lipid homeostasis	Nr1d2	IMP		Mouse	MGI:MGI:5526938|PMID:15623503
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	NR1D2	IDA		Human	PMID:17892483
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	NR1D2	IDA		Human	PMID:17996965
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nr1d2	IDA		Mouse	MGI:MGI:5526909|PMID:23221024
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nr1d2	IMP		Mouse	MGI:MGI:5526936|PMID:19682428
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nr1d2	IMP		Mouse	MGI:MGI:5526938|PMID:15623503
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nr1d2	IMP		Mouse	MGI:MGI:6157418|PMID:29723273
Biological Process	GO:0050728	negative regulation of inflammatory response	Nr1d2	IMP		Mouse	MGI:MGI:6162161|PMID:29533925
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr1d2	IDA		Mouse	MGI:MGI:5905554|PMID:11058961
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Nr1d2	IMP		Mouse	MGI:MGI:5526936|PMID:19682428
Biological Process	GO:0042752	regulation of circadian rhythm	Nr1d2	IDA		Mouse	MGI:MGI:5526909|PMID:23221024
Biological Process	GO:0042752	regulation of circadian rhythm	Nr1d2	IMP		Mouse	MGI:MGI:6162161|PMID:29533925
Biological Process	GO:0006355	regulation of DNA-templated transcription	Nr1d2	IDA		Mouse	PMID:7838158
Biological Process	GO:0006355	regulation of DNA-templated transcription	nr1d2a	IDA		Zfish	PMID:24423866
Biological Process	GO:0050727	regulation of inflammatory response	Nr1d2	IMP		Mouse	MGI:MGI:5526938|PMID:15623503
Biological Process	GO:0019216	regulation of lipid metabolic process	Nr1d2	IMP		Mouse	MGI:MGI:5526938|PMID:15623503
Biological Process	GO:2001014	regulation of skeletal muscle cell differentiation	Nr1d2	IMP		Mouse	MGI:MGI:5526938|PMID:15623503

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern