Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nr1i2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NR1I2
- Mouse genes Nr1i2
- Rat genes Nr1i2
- Zfish genes nr1i2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nr1i2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	NR1I2	IDA		Human	PMID:11114890
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	nr1i2	IDA		Zfish	PMID:16197547
Molecular Function	GO:0004879	nuclear receptor activity	NR1I2	IDA		Human	PMID:12578355
Molecular Function	GO:0004879	nuclear receptor activity	Nr1i2	IDA		Rat	PMID:10967130\|RGD:61490
Molecular Function	GO:0004879	nuclear receptor activity	nr1i2	IDA		Zfish	PMID:16197547
Molecular Function	GO:0004879	nuclear receptor activity	nr1i2	IDA		Zfish	PMID:15718292
Molecular Function	GO:0004879	nuclear receptor activity	nr1i2	IDA		Zfish	PMID:17997857
Molecular Function	GO:0004879	nuclear receptor activity	nr1i2	IDA		Zfish	PMID:11981033
Molecular Function	GO:0004879	nuclear receptor activity	nr1i2	IDA		Zfish	PMID:18384689
Molecular Function	GO:0004879	nuclear receptor activity	nr1i2	IDA		Zfish	PMID:30371853
Molecular Function	GO:0016922	nuclear receptor binding	NR1I2	IDA		Human	PMID:9727070
Molecular Function	GO:0003707	nuclear steroid receptor activity	nr1i2	IDA		Zfish	PMID:17997857
Molecular Function	GO:0003707	nuclear steroid receptor activity	nr1i2	IDA		Zfish	PMID:16197547
Molecular Function	GO:0003707	nuclear steroid receptor activity	nr1i2	IDA		Zfish	PMID:18384689
Molecular Function	GO:0005515	protein binding	NR1I2	IPI	UniProtKB:Q15788	Human	PMID:12578355
Molecular Function	GO:0005515	protein binding	NR1I2	IPI	UniProtKB:O75528	Human	PMID:20413580
Molecular Function	GO:0005515	protein binding	NR1I2	IPI	UniProtKB:P08238	Human	PMID:22939624
Molecular Function	GO:0005515	protein binding	NR1I2	IPI	UniProtKB:Q15788	Human	PMID:23602807
Molecular Function	GO:0005515	protein binding	Nr1i2	IPI	UniProtKB:P97784\|UniProtKB:Q9R194	Mouse	MGI:MGI:5913754\|PMID:28751364
Molecular Function	GO:0005515	protein binding	Nr1i2	IPI	PR:Q00286	Mouse	PMID:11891224
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	NR1I2	IDA		Human	PMID:11114890
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	NR1I2	IDA		Human	PMID:28473536
Cellular Component	GO:0045111	intermediate filament cytoskeleton	NR1I2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	NR1I2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NR1I2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Nr1i2	IDA		Rat	PMID:29204052\|RGD:13782189
Cellular Component	GO:0005667	transcription regulator complex	NR1I2	IPI		Human	PMID:12909012
Cellular Component	GO:0005667	transcription regulator complex	NR1I2	IPI		Human	PMID:23602807
Cellular Component	GO:0005667	transcription regulator complex	Nr1i2	EXP		Mouse	MGI:MGI:6867308\|PMID:17215127
Biological Process	GO:0006351	DNA-templated transcription	nr1i2	IDA		Zfish	PMID:16197547\|ZFIN:ZDB-PUB-051005-2
Biological Process	GO:0006351	DNA-templated transcription	nr1i2	IDA		Zfish	PMID:17997857
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	NR1I2	IDA		Human	PMID:11891224
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NR1I2	IDA		Human	PMID:12578355
Biological Process	GO:0010628	positive regulation of gene expression	Nr1i2	IMP	MGI:MGI:2386087	Mouse	PMID:18794335
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NR1I2	IDA		Human	PMID:11114890
Biological Process	GO:0006355	regulation of DNA-templated transcription	NR1I2	IDA		Human	PMID:9727070
Biological Process	GO:0006355	regulation of DNA-templated transcription	nr1i2	IDA		Zfish	PMID:11981033
Biological Process	GO:0006355	regulation of DNA-templated transcription	nr1i2	IDA		Zfish	PMID:17997857
Biological Process	GO:0006355	regulation of DNA-templated transcription	nr1i2	IDA		Zfish	PMID:18384689
Biological Process	GO:0006355	regulation of DNA-templated transcription	nr1i2	IDA		Zfish	PMID:15718292
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	nr1i2	IDA		Zfish	PMID:16197547\|ZFIN:ZDB-PUB-051005-2
Biological Process	GO:0009636	response to toxic substance	nr1i2	IDA		Zfish	PMID:27207027
Biological Process	GO:0006366	transcription by RNA polymerase II	nr1i2	IDA		Zfish	PMID:16197547
Biological Process	GO:0042178	xenobiotic catabolic process	NR1I2	IDA		Human	PMID:12578355
Biological Process	GO:0006805	xenobiotic metabolic process	NR1I2	IDA		Human	PMID:12578355
Biological Process	GO:0042908	xenobiotic transport	NR1I2	IDA		Human	PMID:12578355

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.