Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NR2C1
  • Mouse genes Nr2c1
  • Rat genes Nr2c1
  • Zfish genes nr2c1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nr2c1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Nr2c1	IDA		Mouse	MGI:MGI:85906|PMID:9071982
Molecular Function	GO:0003677	DNA binding	Nr2c1	IDA		Mouse	MGI:MGI:1306881|PMID:9774688
Molecular Function	GO:0003677	DNA binding	Nr2c1	IDA		Mouse	MGI:MGI:3687713|PMID:9369481
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Nr2c1	IDA		Mouse	MGI:MGI:3687713|PMID:9369481
Molecular Function	GO:0042826	histone deacetylase binding	Nr2c1	IPI	UniProtKB:P56524	Mouse	MGI:MGI:3688049|PMID:11463856
Molecular Function	GO:0005515	protein binding	NR2C1	IPI	UniProtKB:P03372	Human	PMID:12093804
Molecular Function	GO:0005515	protein binding	NR2C1	IPI	UniProtKB:P49116	Human	PMID:17974920
Molecular Function	GO:0005515	protein binding	Nr2c1	IPI	UniProtKB:Q8CBD1|UniProtKB:Q9JHD1	Mouse	MGI:MGI:5284760|PMID:18682553
Molecular Function	GO:0005515	protein binding	Nr2c1	IPI	UniProtKB:O88907|UniProtKB:P63166|UniProtKB:P63280|UniProtKB:Q60953|UniProtKB:Q8CBD1|UniProtKB:Q9JHD1	Mouse	MGI:MGI:5919259|PMID:17187077
Molecular Function	GO:0005515	protein binding	Nr2c1	IPI	UniProtKB:P63166|UniProtKB:Q8BSJ6|UniProtKB:Q8CBD1|UniProtKB:Q9JHD1	Mouse	MGI:MGI:5284760|PMID:18682553
Molecular Function	GO:0005515	protein binding	Nr2c1	IPI	PR:Q8CBD1	Mouse	PMID:9774688
Molecular Function	GO:0042803	protein homodimerization activity	Nr2c1	IPI	UniProtKB:Q505F1	Mouse	MGI:MGI:3687713|PMID:9369481
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nr2c1	IDA		Mouse	MGI:MGI:3687713|PMID:9369481
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	NR2C1	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Nr2c1	IDA		Mouse	MGI:MGI:3715066|PMID:9795341
Cellular Component	GO:0016605	PML body	Nr2c1	IDA		Mouse	MGI:MGI:5284760|PMID:18682553
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nr2c1	IDA		Mouse	MGI:MGI:3687713|PMID:9369481
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nr2c1	IDA		Mouse	MGI:MGI:81983|PMID:8858600
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nr2c1	IDA		Mouse	MGI:MGI:1306881|PMID:9774688
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nr2c1	IDA		Mouse	MGI:MGI:85906|PMID:9071982
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NR2C1	IPI	UniProtKB:P49116	Human	PMID:17974920
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr2c1	IDA		Mouse	MGI:MGI:1306881|PMID:9774688
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr2c1	IDA		Mouse	MGI:MGI:3687713|PMID:9369481
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr2c1	IDA		Mouse	MGI:MGI:81983|PMID:8858600
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr2c1	IDA		Mouse	MGI:MGI:85906|PMID:9071982
Biological Process	GO:0048386	positive regulation of retinoic acid receptor signaling pathway	Nr2c1	IDA		Mouse	MGI:MGI:5285179|PMID:16130175

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern