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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nr2e3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nr2e3
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0001228DNA-binding transcription activator activity, RNA polymerase II-specificNR2E3IMPHumanPMID:22174013
Molecular FunctionGO:0003700DNA-binding transcription factor activityNr2e3IDAMousePMID:15689355
Molecular FunctionGO:0005515protein bindingNR2E3IPIUniProtKB:P61964HumanPMID:32296183
Molecular FunctionGO:0005515protein bindingNr2e3IPIPR:O54751MousePMID:15689355
Molecular FunctionGO:0000978RNA polymerase II cis-regulatory region sequence-specific DNA bindingNR2E3IDAHumanPMID:10220376
Molecular FunctionGO:0043565sequence-specific DNA bindingNR2E3IDAHumanPMID:10220376
Cellular ComponentGO:0005634nucleusNr2e3IDAMousePMID:15689355
Cellular ComponentGO:0005634nucleusnr2e3IDAZfishPMID:15634773
Cellular ComponentGO:0005667transcription regulator complexNr2e3IDAMousePMID:15689355
Biological ProcessGO:0008283cell population proliferationNr2e3IMPMGI:MGI:1346317MousePMID:12407160
Biological ProcessGO:0042462eye photoreceptor cell developmentNr2e3IMPMousePMID:21052544
Biological ProcessGO:0008285negative regulation of cell population proliferationNr2e3IMPMGI:MGI:1346317MousePMID:12407160
Biological ProcessGO:0000122negative regulation of transcription by RNA polymerase IINr2e3IGIMGI:MGI:1194883MousePMID:15689355
Biological ProcessGO:0045494photoreceptor cell maintenancenr2e3IMPZFIN:ZDB-GENO-201130-1ZfishPMID:30684641
Biological ProcessGO:0021982pineal gland developmentnr2e3IMPZFIN:ZDB-MRPHLNO-161003-2ZfishPMID:27317804
Biological ProcessGO:0010628positive regulation of gene expressionNr2e3IGIMGI:MGI:102567MousePMID:15689355
Biological ProcessGO:0010628positive regulation of gene expressionNr2e3IGIMGI:MGI:1194883MousePMID:15689355
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IINR2E3IDAHumanPMID:22174013
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IINR2E3IMPHumanPMID:22174013
Biological ProcessGO:0045944positive regulation of transcription by RNA polymerase IINr2e3IGIMGI:MGI:1194883MousePMID:15689355
Biological ProcessGO:0060041retina development in camera-type eyeNr2e3IMPMGI:MGI:1346317MousePMID:12407160
Biological ProcessGO:0060041retina development in camera-type eyeNr2e3IMPMousePMID:21052544
Biological ProcessGO:0060221retinal rod cell differentiationnr2e3IMPZFIN:ZDB-GENO-201130-1ZfishPMID:30684641

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory