Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NR2F1
  • Mouse genes Nr2f1
  • Rat genes Nr2f1
  • Zfish genes nr2f1a,nr2f1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nr2f1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003700	DNA-binding transcription factor activity	NR2F1	IDA		Human	PMID:10644740
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	NR2F1	IDA		Human	PMID:10644740
Molecular Function	GO:0005515	protein binding	NR2F1	IPI	UniProtKB:P61374	Human	PMID:11043578
Molecular Function	GO:0005515	protein binding	NR2F1	IPI	UniProtKB:Q00403	Human	PMID:1517211
Molecular Function	GO:0044323	retinoic acid-responsive element binding	Nr2f1	IDA		Rat	PMID:7797489|RGD:633499
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	NR2F1	IDA		Human	PMID:10644740
Molecular Function	GO:0043565	sequence-specific DNA binding	NR2F1	IDA		Human	PMID:10644740
Molecular Function	GO:0043565	sequence-specific DNA binding	Nr2f1	IDA		Mouse	PMID:24349493
Molecular Function	GO:0043565	sequence-specific DNA binding	Nr2f1	IDA		Mouse	PMID:7823919
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	NR2F1	IDA		Human	PMID:28473536
Cellular Component	GO:0005829	cytosol	NR2F1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NR2F1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NR2F1	IDA		Human	PMID:10644740
Cellular Component	GO:0005634	nucleus	Nr2f1	IDA		Mouse	PMID:15548577
Biological Process	GO:0035476	angioblast cell migration	nr2f1b	IMP		Zfish	PMID:26572615|ZFIN:ZDB-PUB-151119-11
Biological Process	GO:0055011	atrial cardiac muscle cell differentiation	nr2f1a	IMP	ZFIN:ZDB-GENO-180706-4	Zfish	PMID:29157563
Biological Process	GO:0055011	atrial cardiac muscle cell differentiation	nr2f1a	IMP	ZFIN:ZDB-GENO-180706-8	Zfish	PMID:29157563
Biological Process	GO:0003209	cardiac atrium morphogenesis	nr2f1a	IMP	ZFIN:ZDB-GENO-180706-4	Zfish	PMID:29157563
Biological Process	GO:0003209	cardiac atrium morphogenesis	nr2f1a	IMP	ZFIN:ZDB-GENO-180706-8	Zfish	PMID:29157563
Biological Process	GO:0048738	cardiac muscle tissue development	nr2f1a	IMP	ZFIN:ZDB-GENO-180706-4	Zfish	PMID:30721228
Biological Process	GO:0021796	cerebral cortex regionalization	Nr2f1	IMP	MGI:MGI:3521756	Mouse	PMID:17828260
Biological Process	GO:1904888	cranial skeletal system development	nr2f1b	IGI	ZFIN:ZDB-GENE-990415-252,ZFIN:ZDB-GENE-990415-253	Zfish	PMID:29358039
Biological Process	GO:0001935	endothelial cell proliferation	nr2f1a	IMP	ZFIN:ZDB-MRPHLNO-141201-17	Zfish	PMID:25157918
Biological Process	GO:0001935	endothelial cell proliferation	nr2f1a	IMP	ZFIN:ZDB-MRPHLNO-141201-18	Zfish	PMID:25157918
Biological Process	GO:0030900	forebrain development	Nr2f1	IDA		Mouse	PMID:15548577
Biological Process	GO:1904936	interneuron migration	Nr2f1	IDA		Mouse	PMID:15548577
Biological Process	GO:0010977	negative regulation of neuron projection development	Nr2f1	IMP		Rat	PMID:7797489|RGD:633499
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NR2F1	IDA		Human	PMID:10644740
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr2f1	IDA		Mouse	PMID:7823919
Biological Process	GO:0007399	nervous system development	Nr2f1	IDA		Rat	PMID:7797489|RGD:633499
Biological Process	GO:0001764	neuron migration	Nr2f1	IDA		Mouse	PMID:15548577
Biological Process	GO:1903800	positive regulation of miRNA processing	Nr2f1	IMP	MGI:MGI:2385930	Mouse	PMID:24349493
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nr2f1	IMP		Rat	PMID:7797489|RGD:633499
Biological Process	GO:0010468	regulation of gene expression	Nr2f1	IGI	MGI:MGI:2676825	Mouse	PMID:24349493
Biological Process	GO:0001944	vasculature development	nr2f1b	IMP	ZFIN:ZDB-MRPHLNO-160211-4	Zfish	PMID:26572615
Biological Process	GO:0001944	vasculature development	nr2f1b	IMP	ZFIN:ZDB-MRPHLNO-160211-2	Zfish	PMID:26572615
Biological Process	GO:0001944	vasculature development	nr2f1b	IMP	ZFIN:ZDB-MRPHLNO-160211-3	Zfish	PMID:26572615
Biological Process	GO:0001944	vasculature development	nr2f1a	IMP	ZFIN:ZDB-MRPHLNO-141201-18	Zfish	PMID:25157918
Biological Process	GO:0001944	vasculature development	nr2f1a	IMP	ZFIN:ZDB-MRPHLNO-141201-17	Zfish	PMID:25157918
Biological Process	GO:0060841	venous blood vessel development	nr2f1b	IMP	ZFIN:ZDB-MRPHLNO-160211-4	Zfish	PMID:26572615

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern