Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NR2F2
  • Mouse genes Nr2f2
  • Rat genes Nr2f2
  • Zfish genes nr2f2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nr2f2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Nr2f2	IDA		Mouse	PMID:16912278
Molecular Function	GO:0003700	DNA-binding transcription factor activity	NR2F2	IDA		Human	PMID:9343308
Molecular Function	GO:0004879	nuclear receptor activity	NR2F2	IDA		Human	PMID:18798693
Molecular Function	GO:0005515	protein binding	NR2F2	IPI	UniProtKB:Q15596	Human	PMID:18798693
Molecular Function	GO:0005515	protein binding	NR2F2	IPI	UniProtKB:Q15788	Human	PMID:18798693
Molecular Function	GO:0005515	protein binding	NR2F2	IPI	UniProtKB:Q9UBK2	Human	PMID:18798693
Molecular Function	GO:0005515	protein binding	NR2F2	IPI	UniProtKB:Q9Y6Q9	Human	PMID:18798693
Molecular Function	GO:0005515	protein binding	NR2F2	IPI	UniProtKB:Q92786	Human	PMID:18815287
Molecular Function	GO:0005515	protein binding	NR2F2	IPI	UniProtKB:Q92786	Human	PMID:19210544
Molecular Function	GO:0005515	protein binding	NR2F2	IPI	UniProtKB:Q13485	Human	PMID:23201680
Molecular Function	GO:0005515	protein binding	Nr2f2	IPI	RGD:1306021	Rat	PMID:25687237|RGD:10401852
Molecular Function	GO:0042803	protein homodimerization activity	NR2F2	IPI	UniProtKB:P24468	Human	PMID:18798693
Molecular Function	GO:0001972	retinoic acid binding	NR2F2	IDA		Human	PMID:18798693
Molecular Function	GO:0043565	sequence-specific DNA binding	NR2F2	IDA		Human	PMID:9343308
Molecular Function	GO:0043565	sequence-specific DNA binding	Nr2f2	IDA		Mouse	PMID:7823919
Molecular Function	GO:0043565	sequence-specific DNA binding	Nr2f2	IDA		Rat	PMID:12777384|RGD:737636
Cellular Component	GO:0005829	cytosol	NR2F2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NR2F2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	NR2F2	IDA		Human	PMID:19210544
Cellular Component	GO:0005634	nucleus	Nr2f2	IDA		Mouse	PMID:24466353
Cellular Component	GO:0005634	nucleus	Nr2f2	IDA		Mouse	PMID:19796622
Cellular Component	GO:0005634	nucleus	Nr2f2	IDA		Mouse	PMID:15548577
Cellular Component	GO:0005634	nucleus	Nr2f2	IDA		Rat	PMID:12777384|RGD:737636
Biological Process	GO:0009952	anterior/posterior pattern specification	Nr2f2	IMP	MGI:MGI:3579117,MGI:MGI:3579118	Mouse	PMID:15829524
Biological Process	GO:0048514	blood vessel morphogenesis	Nr2f2	IMP	MGI:MGI:3579116	Mouse	PMID:15875024
Biological Process	GO:0055013	cardiac muscle cell development	nr2f2	IMP	ZFIN:ZDB-GENO-191218-2	Zfish	PMID:30721228
Biological Process	GO:0055013	cardiac muscle cell development	nr2f2	IMP	ZFIN:ZDB-GENO-191218-3	Zfish	PMID:30721228
Biological Process	GO:1904888	cranial skeletal system development	nr2f2	IGI	ZFIN:ZDB-GENE-040426-1438,ZFIN:ZDB-GENE-990415-253	Zfish	PMID:29358039
Biological Process	GO:0008585	female gonad development	NR2F2	IMP		Human	PMID:29478779
Biological Process	GO:0009566	fertilization	Nr2f2	IMP	MGI:MGI:2385933	Mouse	PMID:17404209
Biological Process	GO:0009566	fertilization	Nr2f2	IMP	MGI:MGI:3579117	Mouse	PMID:17404209
Biological Process	GO:0030900	forebrain development	Nr2f2	IDA		Mouse	PMID:15548577
Biological Process	GO:0001701	in utero embryonic development	Nr2f2	IMP	MGI:MGI:3579117	Mouse	PMID:17404209
Biological Process	GO:0001701	in utero embryonic development	Nr2f2	IMP	MGI:MGI:2385933	Mouse	PMID:17404209
Biological Process	GO:1904936	interneuron migration	Nr2f2	IDA		Mouse	PMID:15548577
Biological Process	GO:0001945	lymph vessel development	Nr2f2	IEP		Mouse	MGI:MGI:3838672|PMID:19210544
Biological Process	GO:0001946	lymphangiogenesis	nr2f2	IMP	ZFIN:ZDB-MRPHLNO-110809-1	Zfish	PMID:21641336
Biological Process	GO:0060838	lymphatic endothelial cell fate commitment	NR2F2	IMP		Human	PMID:18815287
Biological Process	GO:0060838	lymphatic endothelial cell fate commitment	nr2f2	IMP	ZFIN:ZDB-MRPHLNO-110809-1	Zfish	PMID:21641336
Biological Process	GO:0001893	maternal placenta development	Nr2f2	IMP	MGI:MGI:3579117	Mouse	PMID:17404209
Biological Process	GO:0001893	maternal placenta development	Nr2f2	IMP	MGI:MGI:2385933	Mouse	PMID:17404209
Biological Process	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	NR2F2	IDA		Human	PMID:19210544
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	NR2F2	IDA		Human	PMID:19210544
Biological Process	GO:0010596	negative regulation of endothelial cell migration	NR2F2	IMP		Human	PMID:19210544
Biological Process	GO:0001937	negative regulation of endothelial cell proliferation	NR2F2	IMP		Human	PMID:19210544
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	NR2F2	IDA		Human	PMID:9343308
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr2f2	IDA		Mouse	PMID:7823919
Biological Process	GO:0001764	neuron migration	Nr2f2	IDA		Mouse	PMID:15548577
Biological Process	GO:0060674	placenta blood vessel development	Nr2f2	IMP	MGI:MGI:2385933	Mouse	PMID:17404209
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NR2F2	IDA		Human	PMID:18798693
Biological Process	GO:0003084	positive regulation of systemic arterial blood pressure	Nr2f2	IMP		Rat	PMID:25687237|RGD:10401852
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NR2F2	IMP		Human	PMID:18815287
Biological Process	GO:0009956	radial pattern formation	Nr2f2	IMP	MGI:MGI:3579117,MGI:MGI:3579118	Mouse	PMID:15829524
Biological Process	GO:0006355	regulation of DNA-templated transcription	Nr2f2	IMP		Rat	PMID:12777384|RGD:737636
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Nr2f2	IDA		Mouse	PMID:19796622
Biological Process	GO:0032355	response to estradiol	Nr2f2	IEP		Rat	PMID:17109907|RGD:1601055
Biological Process	GO:0007519	skeletal muscle tissue development	Nr2f2	IMP	MGI:MGI:3579117,MGI:MGI:3579118	Mouse	PMID:16251273
Biological Process	GO:0060707	trophoblast giant cell differentiation	Nr2f2	IMP	MGI:MGI:2385933	Mouse	PMID:17404209
Biological Process	GO:0060841	venous blood vessel development	nr2f2	IMP	ZFIN:ZDB-MRPHLNO-110809-2	Zfish	PMID:25564648
Biological Process	GO:0060845	venous endothelial cell fate commitment	nr2f2	IMP	ZFIN:ZDB-MRPHLNO-110809-1	Zfish	PMID:24699544

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern