Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Nr4a3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NR4A3
- Mouse genes Nr4a3
- Rat genes Nr4a3
- Zfish genes nr4a3
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nr4a3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035497	cAMP response element binding	Nr4a3	IDA		Mouse	MGI:MGI:5543879\|PMID:23897430
Molecular Function	GO:0003677	DNA binding	Nr4a3	IDA		Rat	PMID:7556683\|RGD:1566537
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	NR4A3	IDA		Human	PMID:20558821
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Nr4a3	IDA		Mouse	MGI:MGI:5295515\|PMID:21868379
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Nr4a3	IDA		Mouse	PMID:19153266
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Nr4a3	IDA		Mouse	PMID:9155013
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Nr4a3	IDA		Rat	PMID:10523643\|RGD:10054079
Molecular Function	GO:0035035	histone acetyltransferase binding	Nr4a3	IPI	UniProtKB:B2RWS6\|UniProtKB:Q9JHD1	Mouse	MGI:MGI:5645210\|PMID:12709428
Molecular Function	GO:0035259	nuclear glucocorticoid receptor binding	Nr4a3	IPI	UniProtKB:P04150	Rat	PMID:15591535\|RGD:10047331
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:O95343	Human	PMID:12543801
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:B2RUY7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:O14633	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:O14817	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:P05187	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:P26371	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:P55273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:P60328	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:P60329	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:P60370	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q05086-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q08AG9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q12805	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q13526	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q5T749	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q5TA82	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q6EMK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q6L8G4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q6L8G9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q6L8H2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q6P9E2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q6UY14-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q8N5G2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q92692-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q92824-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q9BYQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q9BYQ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q9BYQ4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q9BYQ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q9BYR3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q9BYR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q9H2F3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q9H2X0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q9H4F8-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NR4A3	IPI	UniProtKB:Q9Y3S2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Nr4a3	IPI	UniProtKB:Q62318	Rat	PMID:19321449\|RGD:10047236
Molecular Function	GO:0005515	protein binding	Nr4a3	IPI	UniProtKB:P27008	Rat	PMID:25625556\|RGD:10054073
Molecular Function	GO:0042803	protein homodimerization activity	Nr4a3	IDA		Rat	PMID:10523643\|RGD:10054079
Molecular Function	GO:0019901	protein kinase binding	NR4A3	IPI	UniProtKB:P12956	Human	PMID:25852083
Molecular Function	GO:0019901	protein kinase binding	NR4A3	IPI	UniProtKB:P13010	Human	PMID:25852083
Molecular Function	GO:0019901	protein kinase binding	NR4A3	IPI	UniProtKB:P78527	Human	PMID:25852083
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Nr4a3	IDA		Mouse	MGI:MGI:5295515\|PMID:21868379
Molecular Function	GO:0043565	sequence-specific DNA binding	Nr4a3	IDA		Mouse	PMID:8961274
Molecular Function	GO:0001223	transcription coactivator binding	Nr4a3	IPI	UniProtKB:O09000\|UniProtKB:P70365\|UniProtKB:Q61026	Mouse	MGI:MGI:5645210\|PMID:12709428
Molecular Function	GO:0001223	transcription coactivator binding	Nr4a3	IPI	UniProtKB:Q925J9	Mouse	MGI:MGI:5645210\|PMID:12709428
Cellular Component	GO:0005667	transcription regulator complex	Nr4a3	IDA		Mouse	PMID:9155013
Biological Process	GO:0030534	adult behavior	Nr4a3	IMP	MGI:MGI:3037444	Mouse	PMID:11784868
Biological Process	GO:0031100	animal organ regeneration	Nr4a3	IEP		Rat	PMID:7556683\|RGD:1566537
Biological Process	GO:0007411	axon guidance	Nr4a3	IMP	MGI:MGI:3037444	Mouse	PMID:15456880
Biological Process	GO:0007049	cell cycle	Nr4a3	IMP	MGI:MGI:3037444	Mouse	PMID:19153266
Biological Process	GO:0045333	cellular respiration	Nr4a3	IMP		Mouse	MGI:MGI:5645208\|PMID:18325999
Biological Process	GO:0071870	cellular response to catecholamine stimulus	Nr4a3	IDA		Mouse	MGI:MGI:5645208\|PMID:18325999
Biological Process	GO:0071376	cellular response to corticotropin-releasing hormone stimulus	Nr4a3	IDA		Mouse	MGI:MGI:5645213\|PMID:10523643
Biological Process	GO:0044320	cellular response to leptin stimulus	Nr4a3	IDA		Mouse	MGI:MGI:4353981\|PMID:19523439
Biological Process	GO:0035726	common myeloid progenitor cell proliferation	Nr4a3	IMP		Mouse	MGI:MGI:5609505\|PMID:24806827
Biological Process	GO:0097048	dendritic cell apoptotic process	Nr4a3	IMP		Mouse	PMID:19164597
Biological Process	GO:0006351	DNA-templated transcription	Nr4a3	IDA		Mouse	MGI:MGI:4838750\|PMID:19153266
Biological Process	GO:0097009	energy homeostasis	Nr4a3	IMP		Mouse	MGI:MGI:4353981\|PMID:19523439
Biological Process	GO:0097009	energy homeostasis	Nr4a3	IMP		Mouse	MGI:MGI:5543879\|PMID:23897430
Biological Process	GO:0045444	fat cell differentiation	Nr4a3	IDA		Mouse	MGI:MGI:5645207\|PMID:18945812
Biological Process	GO:0007369	gastrulation	Nr4a3	IMP		Mouse	MGI:MGI:3042044\|PMID:13129926
Biological Process	GO:0021766	hippocampus development	Nr4a3	IMP	MGI:MGI:3037444	Mouse	PMID:15456880
Biological Process	GO:0042472	inner ear morphogenesis	Nr4a3	IMP	MGI:MGI:3037444	Mouse	PMID:11784868
Biological Process	GO:0043303	mast cell degranulation	Nr4a3	IMP		Mouse	MGI:MGI:5586645\|PMID:24586680
Biological Process	GO:0001707	mesoderm formation	Nr4a3	IMP	MGI:MGI:3043761	Mouse	PMID:13129926
Biological Process	GO:1903208	negative regulation of hydrogen peroxide-induced neuron death	Nr4a3	IMP		Mouse	MGI:MGI:4462723\|PMID:20566846
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Nr4a3	IMP	MGI:MGI:3037444	Mouse	PMID:15456880
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Nr4a3	IMP		Mouse	PMID:20566846
Biological Process	GO:1903204	negative regulation of oxidative stress-induced neuron death	Nr4a3	IGI	UniProtKB:Q06219	Mouse	MGI:MGI:4462723\|PMID:20566846
Biological Process	GO:0034392	negative regulation of smooth muscle cell apoptotic process	Nr4a3	IMP	MGI:MGI:3037444	Mouse	PMID:19153266
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Nr4a3	IDA		Mouse	MGI:MGI:5543879\|PMID:23897430
Biological Process	GO:0050885	neuromuscular process controlling balance	Nr4a3	IMP	MGI:MGI:3037444	Mouse	PMID:11784868
Biological Process	GO:0051402	neuron apoptotic process	Nr4a3	IMP	MGI:MGI:3037444	Mouse	PMID:15456880
Biological Process	GO:0051402	neuron apoptotic process	Nr4a3	IMP		Mouse	PMID:20566846
Biological Process	GO:0001780	neutrophil homeostasis	nr4a3	IMP	ZFIN:ZDB-MRPHLNO-171026-1	Zfish	PMID:28637666
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	NR4A3	IDA		Human	PMID:23554459
Biological Process	GO:0010613	positive regulation of cardiac muscle hypertrophy	Nr4a3	IMP		Rat	PMID:25625556\|RGD:10054073
Biological Process	GO:0045787	positive regulation of cell cycle	Nr4a3	IMP	MGI:MGI:3037444	Mouse	PMID:19153266
Biological Process	GO:2000670	positive regulation of dendritic cell apoptotic process	Nr4a3	IMP		Mouse	PMID:19164597
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Nr4a3	IDA		Mouse	MGI:MGI:5645210\|PMID:12709428
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Nr4a3	IMP		Mouse	MGI:MGI:2157256\|PMID:11784868
Biological Process	GO:0046321	positive regulation of fatty acid oxidation	Nr4a3	IMP		Mouse	MGI:MGI:5645208\|PMID:18325999
Biological Process	GO:2000253	positive regulation of feeding behavior	Nr4a3	IMP		Mouse	MGI:MGI:4353981\|PMID:19523439
Biological Process	GO:0010828	positive regulation of glucose transmembrane transport	NR4A3	IDA		Human	PMID:24022864
Biological Process	GO:0038097	positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway	Nr4a3	IMP		Mouse	MGI:MGI:5586645\|PMID:24586680
Biological Process	GO:0032765	positive regulation of mast cell cytokine production	Nr4a3	IMP		Mouse	MGI:MGI:5586645\|PMID:24586680
Biological Process	GO:1900625	positive regulation of monocyte aggregation	NR4A3	IMP		Human	PMID:20558821
Biological Process	GO:1900625	positive regulation of monocyte aggregation	Nr4a3	IMP		Mouse	MGI:MGI:5142195\|PMID:20558821
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	Nr4a3	IMP		Mouse	MGI:MGI:5297326\|PMID:16945922
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	NR4A3	IDA		Human	PMID:20558821
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nr4a3	IDA		Mouse	MGI:MGI:5295515\|PMID:21868379
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nr4a3	IGI	MGI:MGI:1352460	Mouse	PMID:15155786
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nr4a3	IDA		Mouse	PMID:15155786
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nr4a3	IDA		Mouse	PMID:9155013
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nr4a3	IDA		Mouse	PMID:8961274
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nr4a3	IDA		Mouse	PMID:19153266
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Nr4a3	IDA		Rat	PMID:19321449\|RGD:10047236
Biological Process	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	NR4A3	IGI	RNAcentral:URS000075DB2F_9606	Human	PMID:23554459
Biological Process	GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	NR4A3	IGI	RNAcentral:URS000075DB2F_9606	Human	PMID:23554459
Biological Process	GO:0009444	pyruvate oxidation	Nr4a3	IMP		Mouse	MGI:MGI:5645208\|PMID:18325999
Biological Process	GO:0048660	regulation of smooth muscle cell proliferation	NR4A3	IDA		Human	PMID:25852083
Biological Process	GO:0061469	regulation of type B pancreatic cell proliferation	Nr4a3	IMP		Rat	PMID:24706823\|RGD:10054075
Biological Process	GO:0042542	response to hydrogen peroxide	Nr4a3	IMP		Mouse	PMID:20566846
Biological Process	GO:0043434	response to peptide hormone	Nr4a3	IEP		Rat	PMID:7556683\|RGD:1566537
Biological Process	GO:0048752	semicircular canal morphogenesis	Nr4a3	IMP	MGI:MGI:3037444	Mouse	PMID:11784868
Biological Process	GO:0034390	smooth muscle cell apoptotic process	Nr4a3	IMP	MGI:MGI:3037444	Mouse	PMID:19153266
Biological Process	GO:0060005	vestibular reflex	Nr4a3	IMP	MGI:MGI:3037444	Mouse	PMID:11784868

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.