Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NRROS
  • Mouse genes Nrros
  • Rat genes Nrros
  • Zfish genes nrros
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nrros

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	Nrros	IPI	UniProtKB:Q61093	Mouse	MGI:MGI:5568138|PMID:24739962
Molecular Function	GO:0050431	transforming growth factor beta binding	NRROS	IPI	UniProtKB:P01137	Human	PMID:29909984
Molecular Function	GO:0050431	transforming growth factor beta binding	Nrros	IPI	UniProtKB:P04202	Mouse	MGI:MGI:6192878|PMID:29909984
Cellular Component	GO:0009986	cell surface	NRROS	IDA		Human	PMID:29909984
Cellular Component	GO:0009986	cell surface	Nrros	IDA		Mouse	MGI:MGI:6192878|PMID:29909984
Cellular Component	GO:0005783	endoplasmic reticulum	Nrros	IDA		Mouse	MGI:MGI:5568138|PMID:24739962
Biological Process	GO:0006955	immune response	Nrros	IMP		Mouse	MGI:MGI:5568138|PMID:24739962
Biological Process	GO:0006954	inflammatory response	Nrros	IMP		Mouse	MGI:MGI:5568138|PMID:24739962
Biological Process	GO:0014005	microglia development	Nrros	IMP		Mouse	MGI:MGI:6192878|PMID:29909984
Biological Process	GO:0014005	microglia development	Nrros	IMP		Mouse	MGI:MGI:6141908|PMID:28459434
Biological Process	GO:0035583	sequestering of TGFbeta in extracellular matrix	Nrros	IDA		Mouse	MGI:MGI:6192878|PMID:29909984
Biological Process	GO:0006801	superoxide metabolic process	Nrros	IMP		Mouse	MGI:MGI:5568138|PMID:24739962
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Nrros	IDA		Mouse	MGI:MGI:6192878|PMID:29909984
Biological Process	GO:0036364	transforming growth factor beta1 activation	Nrros	IDA		Mouse	MGI:MGI:6192878|PMID:29909984

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern