Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NSD3
  • Mouse genes Nsd3
  • Rat genes Nsd3
  • Zfish genes nsd3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nsd3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046976	histone H3K27 methyltransferase activity	Nsd3	IDA		Mouse	PMID:16682010
Molecular Function	GO:0046975	histone H3K36 methyltransferase activity	NSD3	IMP		Human	PMID:21555454
Molecular Function	GO:0140946	histone H3K4 dimethyltransferase activity	NSD3	IDA		Human	PMID:16682010
Molecular Function	GO:0042800	histone H3K4 methyltransferase activity	Nsd3	IDA		Mouse	PMID:16682010
Molecular Function	GO:0005515	protein binding	NSD3	IPI	UniProtKB:P45973	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	NSD3	IPI	UniProtKB:O60885	Human	PMID:21555454
Molecular Function	GO:0005515	protein binding	NSD3	IPI	UniProtKB:O95391	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	NSD3	IPI	UniProtKB:P09017	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	NSD3	IPI	UniProtKB:P41218	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	NSD3	IPI	UniProtKB:Q9UER7	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	NSD3	IPI	UniProtKB:Q6P2C6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NSD3	IPI	UniProtKB:V9HWG0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NSD3	IPI	UniProtKB:P03372	Human	PMID:25640309
Molecular Function	GO:0005515	protein binding	NSD3	IPI	UniProtKB:Q06609	Human	PMID:25640309
Molecular Function	GO:0005515	protein binding	NSD3	IPI	UniProtKB:Q13315	Human	PMID:25640309
Molecular Function	GO:0005515	protein binding	NSD3	IPI	UniProtKB:O60885	Human	PMID:29176719
Molecular Function	GO:0005515	protein binding	NSD3	IPI	UniProtKB:P03372	Human	PMID:31527615
Molecular Function	GO:0005515	protein binding	NSD3	IPI	UniProtKB:P45973	Human	PMID:32814053
Molecular Function	GO:0140537	transcription regulator activator activity	NSD3	IMP		Human	PMID:21555454
Cellular Component	GO:0005634	nucleus	NSD3	IMP		Human	PMID:21555454
Biological Process	GO:0016570	histone modification	Nsd3	IDA		Mouse	MGI:MGI:3625557|PMID:16682010
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Nsd3	IDA		Mouse	PMID:16682010
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	NSD3	IMP		Human	PMID:21555454

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern