Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NT5C
  • Mouse genes Nt5c
  • Rat genes Nt5c
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nt5c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008253	5'-nucleotidase activity	Nt5c	IDA		Mouse	PMID:10681516
Molecular Function	GO:0008253	5'-nucleotidase activity	Nt5c	IDA		Mouse	PMID:6301357
Molecular Function	GO:0042802	identical protein binding	NT5C	IPI	UniProtKB:Q8TCD5	Human	PMID:31515488
Molecular Function	GO:0042802	identical protein binding	NT5C	IPI	UniProtKB:Q8TCD5	Human	PMID:32296183
Molecular Function	GO:0050483	IMP 5'-nucleotidase activity	Nt5c	IDA		Mouse	PMID:6301357
Molecular Function	GO:0008252	nucleotidase activity	NT5C	IDA		Human	PMID:10681516
Molecular Function	GO:0016791	phosphatase activity	Nt5c	IDA		Mouse	PMID:1914521
Molecular Function	GO:0019103	pyrimidine nucleotide binding	NT5C	IDA		Human	PMID:10681516
Cellular Component	GO:0005737	cytoplasm	NT5C	IDA		Human	PMID:10681516
Cellular Component	GO:0005829	cytosol	NT5C	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Nt5c	IDA		Mouse	PMID:10681516
Cellular Component	GO:0070062	extracellular exosome	NT5C	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	NT5C	HDA		Human	PMID:23533145
Cellular Component	GO:0005739	mitochondrion	Nt5c	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005634	nucleus	NT5C	IDA		Human	PMID:10681516
Biological Process	GO:0000255	allantoin metabolic process	Nt5c	IDA		Mouse	PMID:10681516
Biological Process	GO:0000255	allantoin metabolic process	Nt5c	IDA		Mouse	PMID:6301357
Biological Process	GO:0043605	amide catabolic process	Nt5c	IDA		Mouse	PMID:10681516
Biological Process	GO:0043605	amide catabolic process	Nt5c	IDA		Mouse	PMID:6301357
Biological Process	GO:0006249	dCMP catabolic process	Nt5c	IDA		Mouse	PMID:6301357
Biological Process	GO:0009264	deoxyribonucleotide catabolic process	Nt5c	IDA		Mouse	PMID:10681516
Biological Process	GO:0016311	dephosphorylation	NT5C	IDA		Human	PMID:10681516
Biological Process	GO:0046055	dGMP catabolic process	Nt5c	IDA		Mouse	PMID:10681516
Biological Process	GO:0046074	dTMP catabolic process	Nt5c	IDA		Mouse	PMID:6301357
Biological Process	GO:0046079	dUMP catabolic process	Nt5c	IDA		Mouse	PMID:10681516
Biological Process	GO:0006204	IMP catabolic process	Nt5c	IDA		Mouse	PMID:6301357
Biological Process	GO:0009223	pyrimidine deoxyribonucleotide catabolic process	NT5C	IDA		Human	PMID:10681516
Biological Process	GO:0046050	UMP catabolic process	Nt5c	IDA		Mouse	PMID:10681516

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern