Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NT5C2
  • Mouse genes Nt5c2
  • Rat genes Nt5c2
  • Zfish genes nt5c2a,nt5c2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nt5c2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008253	5'-nucleotidase activity	NT5C2	IDA		Human	PMID:1659319
Molecular Function	GO:0008253	5'-nucleotidase activity	NT5C2	IDA		Human	PMID:21873433
Molecular Function	GO:0008253	5'-nucleotidase activity	NT5C2	IDA		Human	PMID:9371705
Molecular Function	GO:0008253	5'-nucleotidase activity	Nt5c2	IDA		Rat	PMID:12675911|RGD:2291861
Molecular Function	GO:0008253	5'-nucleotidase activity	Nt5c2	IDA		Rat	PMID:6260203|RGD:151356611
Molecular Function	GO:0005524	ATP binding	NT5C2	IDA		Human	PMID:21396942
Molecular Function	GO:0050484	GMP 5'-nucleotidase activity	Nt5c2	IDA		Mouse	PMID:5560407
Molecular Function	GO:0050484	GMP 5'-nucleotidase activity	Nt5c2	IDA		Rat	PMID:6260203|RGD:151356611
Molecular Function	GO:0042802	identical protein binding	NT5C2	IDA		Human	PMID:10092873
Molecular Function	GO:0042802	identical protein binding	NT5C2	IDA		Human	PMID:21396942
Molecular Function	GO:0050483	IMP 5'-nucleotidase activity	NT5C2	IDA		Human	PMID:10092873
Molecular Function	GO:0050483	IMP 5'-nucleotidase activity	NT5C2	IDA		Human	PMID:1659319
Molecular Function	GO:0050483	IMP 5'-nucleotidase activity	NT5C2	IDA		Human	PMID:21873433
Molecular Function	GO:0050483	IMP 5'-nucleotidase activity	NT5C2	IDA		Human	PMID:9371705
Molecular Function	GO:0050483	IMP 5'-nucleotidase activity	Nt5c2	IDA		Rat	PMID:6260203|RGD:151356611
Molecular Function	GO:0050146	nucleoside phosphotransferase activity	NT5C2	IDA		Human	PMID:1659319
Molecular Function	GO:0050146	nucleoside phosphotransferase activity	NT5C2	IDA		Human	PMID:9371705
Molecular Function	GO:0005515	protein binding	NT5C2	IPI	UniProtKB:P51116	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	NT5C2	IPI	UniProtKB:Q6ZVK8	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	NT5C2	IPI	UniProtKB:Q86TA1	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	NT5C2	IPI	UniProtKB:Q9Y5B8	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	NT5C2	IPI	UniProtKB:P51116	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	NT5C2	IPI	UniProtKB:Q6ZVK8	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	NT5C2	IPI	UniProtKB:Q86TA1	Human	PMID:19060904
Molecular Function	GO:0005515	protein binding	NT5C2	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NT5C2	IPI	UniProtKB:P48047	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NT5C2	IPI	UniProtKB:Q70IA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NT5C2	IPI	UniProtKB:Q7L9L4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NT5C2	IPI	UniProtKB:Q9Y5B8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	NT5C2	IPI	UniProtKB:Q8IVS8	Human	PMID:32296183
Molecular Function	GO:0061630	ubiquitin protein ligase activity	NT5C2	IDA		Human	PMID:36159777
Cellular Component	GO:0005737	cytoplasm	NT5C2	IDA		Human	PMID:9371705
Cellular Component	GO:0005829	cytosol	NT5C2	IDA		Human	PMID:21873433
Cellular Component	GO:0005829	cytosol	NT5C2	IDA		Human	PMID:9371705
Cellular Component	GO:0005829	cytosol	Nt5c2	IDA		Mouse	PMID:11690631
Biological Process	GO:0046085	adenosine metabolic process	Nt5c2	IDA		Rat	PMID:12675911|RGD:2291861
Biological Process	GO:0000255	allantoin metabolic process	NT5C2	IDA		Human	PMID:21873433
Biological Process	GO:0000255	allantoin metabolic process	Nt5c2	IDA		Mouse	PMID:5560407
Biological Process	GO:0043605	amide catabolic process	Nt5c2	IDA		Mouse	PMID:5560407
Biological Process	GO:0046055	dGMP catabolic process	Nt5c2	IDA		Mouse	PMID:5560407
Biological Process	GO:0046054	dGMP metabolic process	NT5C2	IDA		Human	PMID:1659319
Biological Process	GO:0046054	dGMP metabolic process	NT5C2	IDA		Human	PMID:9371705
Biological Process	GO:0046054	dGMP metabolic process	Nt5c2	IDA		Rat	PMID:6260203|RGD:151356611
Biological Process	GO:0046038	GMP catabolic process	Nt5c2	IDA		Mouse	PMID:5560407
Biological Process	GO:0006202	GMP catabolic process to guanine	Nt5c2	IDA		Mouse	PMID:5560407
Biological Process	GO:0046037	GMP metabolic process	NT5C2	IDA		Human	PMID:1659319
Biological Process	GO:0046037	GMP metabolic process	NT5C2	IDA		Human	PMID:9371705
Biological Process	GO:0046037	GMP metabolic process	Nt5c2	IDA		Rat	PMID:6260203|RGD:151356611
Biological Process	GO:0006204	IMP catabolic process	NT5C2	IDA		Human	PMID:21873433
Biological Process	GO:0046040	IMP metabolic process	NT5C2	IDA		Human	PMID:10092873
Biological Process	GO:0046040	IMP metabolic process	NT5C2	IDA		Human	PMID:1659319
Biological Process	GO:0046040	IMP metabolic process	NT5C2	IDA		Human	PMID:9371705
Biological Process	GO:0046040	IMP metabolic process	Nt5c2	IDA		Rat	PMID:19913594|RGD:2317226
Biological Process	GO:0046040	IMP metabolic process	Nt5c2	IDA		Rat	PMID:6260203|RGD:151356611
Biological Process	GO:0050689	negative regulation of defense response to virus by host	NT5C2	IDA		Human	PMID:36159777
Biological Process	GO:0070936	protein K48-linked ubiquitination	NT5C2	IDA		Human	PMID:36159777

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern