Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NT5E
  • Mouse genes Nt5e
  • Rat genes Nt5e
  • Zfish genes nt5e
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nt5e

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0002953	5'-deoxynucleotidase activity	NT5E	IDA		Human	PMID:22997138
Molecular Function	GO:0002953	5'-deoxynucleotidase activity	NT5E	IDA		Human	PMID:34403084
Molecular Function	GO:0008253	5'-nucleotidase activity	NT5E	IDA		Human	PMID:22997138
Molecular Function	GO:0008253	5'-nucleotidase activity	NT5E	IDA		Human	PMID:23142347
Molecular Function	GO:0008253	5'-nucleotidase activity	NT5E	IMP		Human	PMID:24887587
Molecular Function	GO:0008253	5'-nucleotidase activity	NT5E	IDA		Human	PMID:28592560
Molecular Function	GO:0008253	5'-nucleotidase activity	NT5E	IDA		Human	PMID:34403084
Molecular Function	GO:0008253	5'-nucleotidase activity	NT5E	IDA		Human	PMID:7595232
Molecular Function	GO:0008253	5'-nucleotidase activity	Nt5e	IDA		Mouse	MGI:MGI:66655|PMID:8224905
Molecular Function	GO:0008253	5'-nucleotidase activity	Nt5e	IMP	MGI:MGI:3522017	Mouse	PMID:28746349
Molecular Function	GO:0008253	5'-nucleotidase activity	Nt5e	IMP		Mouse	PMID:20430891
Molecular Function	GO:0008253	5'-nucleotidase activity	Nt5e	IMP	MGI:MGI:3522017	Mouse	PMID:16547283
Molecular Function	GO:0008253	5'-nucleotidase activity	Nt5e	IDA		Rat	PMID:11935367|RGD:631915
Molecular Function	GO:0008253	5'-nucleotidase activity	Nt5e	IDA		Rat	PMID:12675911|RGD:2291861
Molecular Function	GO:0008253	5'-nucleotidase activity	Nt5e	IDA		Rat	PMID:1770988|RGD:155230694
Molecular Function	GO:0008253	5'-nucleotidase activity	Nt5e	IDA		Rat	PMID:6017738|RGD:10047240
Molecular Function	GO:0008198	ferrous iron binding	Nt5e	IDA		Rat	PMID:11935367|RGD:631915
Molecular Function	GO:0050484	GMP 5'-nucleotidase activity	NT5E	IDA		Human	PMID:22997138
Molecular Function	GO:0050484	GMP 5'-nucleotidase activity	NT5E	IDA		Human	PMID:34403084
Molecular Function	GO:0042802	identical protein binding	NT5E	IDA		Human	PMID:22997138
Molecular Function	GO:0042802	identical protein binding	NT5E	IDA		Human	PMID:23142347
Molecular Function	GO:0042802	identical protein binding	NT5E	IDA		Human	PMID:34403084
Molecular Function	GO:0050483	IMP 5'-nucleotidase activity	NT5E	IDA		Human	PMID:22997138
Molecular Function	GO:0050483	IMP 5'-nucleotidase activity	NT5E	IDA		Human	PMID:34403084
Molecular Function	GO:0005515	protein binding	NT5E	IPI	UniProtKB:Q8WWF5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NT5E	IPI	UniProtKB:Q9Y225-2	Human	PMID:32296183
Molecular Function	GO:0050340	thymidylate 5'-phosphatase activity	NT5E	IDA		Human	PMID:22997138
Molecular Function	GO:0008270	zinc ion binding	NT5E	IDA		Human	PMID:22997138
Molecular Function	GO:0008270	zinc ion binding	NT5E	IDA		Human	PMID:23142347
Molecular Function	GO:0008270	zinc ion binding	NT5E	IDA		Human	PMID:34403084
Cellular Component	GO:0009986	cell surface	NT5E	HDA		Human	PMID:19581412
Cellular Component	GO:0009986	cell surface	Nt5e	IDA		Rat	PMID:21627568|RGD:5134342
Cellular Component	GO:0005829	cytosol	NT5E	IDA		Human	GO_REF:0000052
Cellular Component	GO:0009897	external side of plasma membrane	Nt5e	IMP	MGI:MGI:3522017	Mouse	PMID:28746349
Cellular Component	GO:0070062	extracellular exosome	NT5E	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	NT5E	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	NT5E	HDA		Human	PMID:21362503
Cellular Component	GO:0070062	extracellular exosome	NT5E	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	NT5E	IDA		Human	PMID:2129526
Cellular Component	GO:0016020	membrane	Nt5e	IDA		Mouse	PMID:16547283
Cellular Component	GO:0005654	nucleoplasm	NT5E	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	NT5E	IDA		Human	PMID:25644539
Cellular Component	GO:0005886	plasma membrane	NT5E	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Nt5e	IDA		Mouse	PMID:11375348
Cellular Component	GO:0005886	plasma membrane	Nt5e	IDA		Rat	PMID:1770988|RGD:155230694
Cellular Component	GO:0005886	plasma membrane	Nt5e	IDA		Rat	PMID:6017738|RGD:10047240
Cellular Component	GO:0097060	synaptic membrane	Nt5e	IDA		Rat	PMID:21414400|RGD:5134346
Biological Process	GO:0046086	adenosine biosynthetic process	Nt5e	IMP	MGI:MGI:3522017	Mouse	PMID:16547283
Biological Process	GO:0046086	adenosine biosynthetic process	Nt5e	IMP		Rat	PMID:30269308|RGD:152995394
Biological Process	GO:0046085	adenosine metabolic process	Nt5e	IDA		Rat	PMID:12675911|RGD:2291861
Biological Process	GO:0046032	ADP catabolic process	Nt5e	IMP	MGI:MGI:3522017	Mouse	PMID:28746349
Biological Process	GO:0046032	ADP catabolic process	Nt5e	IMP		Mouse	PMID:20430891
Biological Process	GO:0006196	AMP catabolic process	Nt5e	IMP	MGI:MGI:3522017	Mouse	PMID:28746349
Biological Process	GO:0006196	AMP catabolic process	Nt5e	IMP		Mouse	PMID:20430891
Biological Process	GO:0006196	AMP catabolic process	Nt5e	IMP	MGI:MGI:3522017	Mouse	PMID:16547283
Biological Process	GO:0006196	AMP catabolic process	Nt5e	IDA		Rat	PMID:21414400|RGD:5134346
Biological Process	GO:0006196	AMP catabolic process	Nt5e	IMP		Rat	PMID:30269308|RGD:152995394
Biological Process	GO:0046034	ATP metabolic process	NT5E	IDA		Human	PMID:25644539
Biological Process	GO:0007420	brain development	Nt5e	IEP		Rat	PMID:21414400|RGD:5134346
Biological Process	GO:0055074	calcium ion homeostasis	Nt5e	IGI	MGI:MGI:1351634	Mouse	PMID:28592560
Biological Process	GO:0140928	inhibition of non-skeletal tissue mineralization	Nt5e	IMP		Mouse	PMID:25644539
Biological Process	GO:0007159	leukocyte cell-cell adhesion	NT5E	IDA		Human	PMID:7595232
Biological Process	GO:0050728	negative regulation of inflammatory response	Nt5e	IMP	MGI:MGI:3522017	Mouse	PMID:16547283
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	Nt5e	IEP		Rat	PMID:21372807|RGD:5134347
Biological Process	GO:0010044	response to aluminum ion	Nt5e	IEP		Rat	PMID:17686601|RGD:5134345
Biological Process	GO:0033198	response to ATP	NT5E	IDA		Human	PMID:25644539
Biological Process	GO:0046688	response to copper ion	nt5e	IDA		Zfish	PMID:17499414
Biological Process	GO:0010035	response to inorganic substance	NT5E	IDA		Human	PMID:25644539

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern