Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NTF3
  • Mouse genes Ntf3
  • Rat genes Ntf3
  • Zfish genes ntf3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ntf3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042056	chemoattractant activity	NTF3	IDA		Human	PMID:23027130
Molecular Function	GO:0008083	growth factor activity	NTF3	IDA		Human	PMID:23027130
Molecular Function	GO:0048406	nerve growth factor binding	Ntf3	IMP		Rat	PMID:2164684|RGD:729140
Molecular Function	GO:0005515	protein binding	NTF3	IPI	UniProtKB:P07174	Human	PMID:18596692
Molecular Function	GO:0005515	protein binding	NTF3	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Ntf3	IPI	PR:Q6VNS1	Mouse	PMID:11684666
Molecular Function	GO:0005515	protein binding	Ntf3	IPI	PR:Q9Z0W1	Mouse	PMID:11684666
Molecular Function	GO:0005515	protein binding	Ntf3	IPI	PR:P15209	Mouse	PMID:11684666
Cellular Component	GO:0031410	cytoplasmic vesicle	Ntf3	IDA		Mouse	PMID:14715936
Biological Process	GO:0090630	activation of GTPase activity	NTF3	IDA		Human	PMID:23027130
Biological Process	GO:0032148	activation of protein kinase B activity	NTF3	IDA		Human	PMID:23027130
Biological Process	GO:0007411	axon guidance	Ntf3	IDA		Mouse	PMID:15550985
Biological Process	GO:0007411	axon guidance	Ntf3	IMP	MGI:MGI:1933844	Mouse	PMID:15550985
Biological Process	GO:0007411	axon guidance	Ntf3	IMP		Mouse	PMID:8861722
Biological Process	GO:0007420	brain development	Ntf3	IMP	MGI:MGI:1861706	Mouse	PMID:10195193
Biological Process	GO:0048484	enteric nervous system development	Ntf3	IMP	MGI:MGI:1933844	Mouse	PMID:15497153
Biological Process	GO:0008544	epidermis development	Ntf3	IMP	MGI:MGI:1857232	Mouse	PMID:9736028
Biological Process	GO:0048699	generation of neurons	Ntf3	IGI	MGI:MGI:97385	Mouse	PMID:16142215
Biological Process	GO:0007403	glial cell fate determination	Ntf3	IMP	MGI:MGI:1933844	Mouse	PMID:10384880
Biological Process	GO:0050930	induction of positive chemotaxis	NTF3	IDA		Human	PMID:23027130
Biological Process	GO:0042490	mechanoreceptor differentiation	Ntf3	IGI	MGI:MGI:88145	Mouse	PMID:15376326
Biological Process	GO:0042490	mechanoreceptor differentiation	Ntf3	IGI	MGI:MGI:97381	Mouse	PMID:15376326
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Ntf3	IDA		Rat	PMID:14507970|RGD:1358327
Biological Process	GO:0042552	myelination	Ntf3	IDA		Rat	PMID:15139015|RGD:1358328
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Ntf3	IMP		Mouse	PMID:19915564
Biological Process	GO:0050732	negative regulation of peptidyl-tyrosine phosphorylation	NTF3	IDA		Human	PMID:23027130
Biological Process	GO:0043069	negative regulation of programmed cell death	ntf3	IMP		Zfish	PMID:11023682
Biological Process	GO:0021675	nerve development	Ntf3	IMP	MGI:MGI:1857232	Mouse	PMID:7605630
Biological Process	GO:0007399	nervous system development	Ntf3	IMP		Rat	PMID:2164684|RGD:729140
Biological Process	GO:0007274	neuromuscular synaptic transmission	Ntf3	IDA		Mouse	PMID:11978828
Biological Process	GO:0051402	neuron apoptotic process	Ntf3	IMP		Mouse	PMID:19915564
Biological Process	GO:0048666	neuron development	Ntf3	IMP	MGI:MGI:2388319	Mouse	PMID:8809809
Biological Process	GO:0007422	peripheral nervous system development	Ntf3	IMP	MGI:MGI:1857232	Mouse	PMID:8630254
Biological Process	GO:0007422	peripheral nervous system development	Ntf3	IMP	MGI:MGI:1857232	Mouse	PMID:12741988
Biological Process	GO:0007422	peripheral nervous system development	ntf3	IMP		Zfish	PMID:11023682
Biological Process	GO:2000251	positive regulation of actin cytoskeleton reorganization	NTF3	IDA		Human	PMID:23027130
Biological Process	GO:0030335	positive regulation of cell migration	NTF3	IDA		Human	PMID:23027130
Biological Process	GO:0008284	positive regulation of cell population proliferation	NTF3	IDA		Human	PMID:23027130
Biological Process	GO:0045687	positive regulation of glial cell differentiation	Ntf3	IDA		Rat	PMID:15139015|RGD:1358328
Biological Process	GO:0043406	positive regulation of MAP kinase activity	NTF3	IDA		Human	PMID:23027130
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	NTF3	IDA		Human	PMID:23027130
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	NTF3	IDA		Human	PMID:23027130
Biological Process	GO:0002092	positive regulation of receptor internalization	NTF3	IDA		Human	PMID:23027130
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ntf3	IDA		Mouse	PMID:12741988
Biological Process	GO:0042981	regulation of apoptotic process	NTF3	IGI	UniProtKB:Q6VNS1	Human	PMID:23954828
Biological Process	GO:0043523	regulation of neuron apoptotic process	Ntf3	IDA		Mouse	PMID:16516892
Biological Process	GO:0035902	response to immobilization stress	Ntf3	IEP		Rat	PMID:7568018|RGD:150520015
Biological Process	GO:0051145	smooth muscle cell differentiation	Ntf3	IMP	MGI:MGI:1933844	Mouse	PMID:15497153
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	NTF3	IDA		Human	PMID:23027130

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern