Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Ntrk3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes NTRK3
- Mouse genes Ntrk3
- Rat genes Ntrk3
- Zfish genes ntrk3a,ntrk3b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ntrk3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005004	GPI-linked ephrin receptor activity	Ntrk3	IDA		Rat	PMID:19036963\|RGD:8553786
Molecular Function	GO:0005030	neurotrophin receptor activity	NTRK3	IDA		Human	PMID:23027130
Molecular Function	GO:0002039	p53 binding	NTRK3	IPI	UniProtKB:P04637	Human	PMID:23027130
Molecular Function	GO:0005515	protein binding	NTRK3	IPI	UniProtKB:P18031	Human	PMID:12237455
Molecular Function	GO:0005515	protein binding	NTRK3	IPI	UniProtKB:Q6PKX4	Human	PMID:20565848
Molecular Function	GO:0005515	protein binding	NTRK3	IPI	UniProtKB:Q99523	Human	PMID:21102451
Molecular Function	GO:0005515	protein binding	NTRK3	IPI	UniProtKB:P04629	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	NTRK3	IPI	UniProtKB:P08581	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	NTRK3	IPI	UniProtKB:P18031	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	NTRK3	IPI	UniProtKB:P61619	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	NTRK3	IPI	UniProtKB:Q15375	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	NTRK3	IPI	UniProtKB:Q16620	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	NTRK3	IPI	UniProtKB:Q16832	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	NTRK3	IPI	UniProtKB:Q9UBV2	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	Ntrk3	IPI	UniProtKB:P16056	Mouse	MGI:MGI:7258354\|PMID:27086544
Molecular Function	GO:0005515	protein binding	Ntrk3	IPI	UniProtKB:Q2MHE5	Mouse	MGI:MGI:5689982\|PMID:20565848
Molecular Function	GO:0005515	protein binding	Ntrk3	IPI	PR:Q91ZM9	Mouse	PMID:23954828
Molecular Function	GO:0005515	protein binding	Ntrk3	IPI	PR:P20181	Mouse	PMID:11684666
Molecular Function	GO:0005515	protein binding	Ntrk3	IPI	UniProtKB:Q03114	Rat	PMID:17341134\|RGD:13432345
Molecular Function	GO:0005515	protein binding	Ntrk3	IPI	UniProtKB:Q9ESN9	Rat	PMID:21775604\|RGD:13673858
Molecular Function	GO:0005515	protein binding	Ntrk3	IPI	RGD:3347\|RGD:619787	Rat	PMID:22764246\|RGD:10044012
Cellular Component	GO:0005737	cytoplasm	Ntrk3	IDA		Mouse	PMID:10207144
Cellular Component	GO:0005737	cytoplasm	Ntrk3	IDA		Rat	PMID:19584175\|RGD:150520016
Cellular Component	GO:0098978	glutamatergic synapse	Ntrk3	EXP		Rat	PMID:21262467\|RGD:13702219
Cellular Component	GO:0098978	glutamatergic synapse	Ntrk3	IDA		Rat	PMID:21262467\|RGD:13702219
Cellular Component	GO:0098978	glutamatergic synapse	Ntrk3	IMP		Rat	PMID:21262467\|RGD:13702219
Cellular Component	GO:0016020	membrane	Ntrk3	IDA		Rat	PMID:12882781\|RGD:2325632
Cellular Component	GO:0005886	plasma membrane	Ntrk3	IDA		Rat	PMID:17532148\|RGD:2325627
Cellular Component	GO:0045211	postsynaptic membrane	Ntrk3	IDA		Rat	PMID:21262467\|RGD:13702219
Cellular Component	GO:0045211	postsynaptic membrane	Ntrk3	IMP		Rat	PMID:21262467\|RGD:13702219
Cellular Component	GO:0043235	receptor complex	NTRK3	IDA		Human	PMID:23382219
Biological Process	GO:0090630	activation of GTPase activity	NTRK3	IDA		Human	PMID:23027130
Biological Process	GO:0032148	activation of protein kinase B activity	NTRK3	IDA		Human	PMID:23027130
Biological Process	GO:0048677	axon extension involved in regeneration	Ntrk3	IGI	MGI:MGI:97380	Mouse	PMID:16142215
Biological Process	GO:0071300	cellular response to retinoic acid	Ntrk3	IEP		Rat	PMID:10027563\|RGD:2325652
Biological Process	GO:0007417	central nervous system development	ntrk3a	IEP		Zfish	PMID:9520329
Biological Process	GO:0007623	circadian rhythm	Ntrk3	IEP		Mouse	MGI:MGI:5503234\|PMID:23785138
Biological Process	GO:0090102	cochlea development	Ntrk3	IEP		Rat	PMID:10494076\|RGD:2325650
Biological Process	GO:0007507	heart development	NTRK3	IMP		Human	PMID:25196463
Biological Process	GO:0070306	lens fiber cell differentiation	Ntrk3	IGI	MGI:MGI:1100860	Mouse	PMID:23136392
Biological Process	GO:0042490	mechanoreceptor differentiation	Ntrk3	IMP	MGI:MGI:1888375	Mouse	PMID:15376326
Biological Process	GO:0022011	myelination in peripheral nervous system	Ntrk3	IGI	MGI:MGI:97631	Mouse	PMID:20553714
Biological Process	GO:0022011	myelination in peripheral nervous system	Ntrk3	IGI	MGI:MGI:97384	Mouse	PMID:20553714
Biological Process	GO:0043066	negative regulation of apoptotic process	ntrk3a	IEP		Zfish	PMID:11023682
Biological Process	GO:0048712	negative regulation of astrocyte differentiation	Ntrk3	IMP		Rat	PMID:12075995\|RGD:2325633
Biological Process	GO:0001933	negative regulation of protein phosphorylation	NTRK3	IDA		Human	PMID:23027130
Biological Process	GO:0048665	neuron fate specification	Ntrk3	IMP		Rat	PMID:15247919\|RGD:2325628
Biological Process	GO:0001764	neuron migration	Ntrk3	IMP		Rat	PMID:12075995\|RGD:2325633
Biological Process	GO:0019227	neuronal action potential propagation	Ntrk3	IGI	MGI:MGI:97631	Mouse	PMID:20553714
Biological Process	GO:0019227	neuronal action potential propagation	Ntrk3	IGI	MGI:MGI:97384	Mouse	PMID:20553714
Biological Process	GO:2000251	positive regulation of actin cytoskeleton reorganization	NTRK3	IDA		Human	PMID:23027130
Biological Process	GO:0043065	positive regulation of apoptotic process	Ntrk3	IDA		Mouse	PMID:23954828
Biological Process	GO:0048691	positive regulation of axon extension involved in regeneration	Ntrk3	IGI	MGI:MGI:97380	Mouse	PMID:16142215
Biological Process	GO:0030335	positive regulation of cell migration	NTRK3	IDA		Human	PMID:23027130
Biological Process	GO:0008284	positive regulation of cell population proliferation	NTRK3	IDA		Human	PMID:23027130
Biological Process	GO:0010628	positive regulation of gene expression	NTRK3	IDA		Human	PMID:23027130
Biological Process	GO:0043406	positive regulation of MAP kinase activity	NTRK3	IDA		Human	PMID:23027130
Biological Process	GO:0010976	positive regulation of neuron projection development	Ntrk3	IDA		Rat	PMID:8494647\|RGD:729049
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	NTRK3	IDA		Human	PMID:23027130
Biological Process	GO:0050927	positive regulation of positive chemotaxis	NTRK3	IDA		Human	PMID:23027130
Biological Process	GO:0051965	positive regulation of synapse assembly	Ntrk3	IDA		Mouse	PMID:24613359
Biological Process	GO:0097107	postsynaptic density assembly	Ntrk3	EXP		Rat	PMID:21262467\|RGD:13702219
Biological Process	GO:0097107	postsynaptic density assembly	Ntrk3	IDA		Rat	PMID:21262467\|RGD:13702219
Biological Process	GO:2000177	regulation of neural precursor cell proliferation	Ntrk3	IMP		Rat	PMID:12075995\|RGD:2325633
Biological Process	GO:1905606	regulation of presynapse assembly	Ntrk3	IDA		Rat	PMID:21262467\|RGD:13702219
Biological Process	GO:1905606	regulation of presynapse assembly	Ntrk3	IMP		Rat	PMID:21262467\|RGD:13702219
Biological Process	GO:0048678	response to axon injury	Ntrk3	IEP		Rat	PMID:17532148\|RGD:2325627
Biological Process	GO:0051412	response to corticosterone	Ntrk3	IEP		Rat	PMID:14557907\|RGD:2325630
Biological Process	GO:0045471	response to ethanol	Ntrk3	IEP		Rat	PMID:11743997\|RGD:2325642
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	NTRK3	IDA		Human	PMID:23027130

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.