Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NTSR1
  • Mouse genes Ntsr1
  • Rat genes Ntsr1
  • Zfish genes ntsr1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ntsr1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016492	G protein-coupled neurotensin receptor activity	NTSR1	IDA		Human	PMID:21725197
Molecular Function	GO:0016492	G protein-coupled neurotensin receptor activity	NTSR1	IMP		Human	PMID:8381365
Molecular Function	GO:0042802	identical protein binding	NTSR1	IPI	UniProtKB:P30989	Human	PMID:17620610
Molecular Function	GO:0042802	identical protein binding	Ntsr1	IPI	RGD:1306076	Rat	PMID:17188644|RGD:9743899
Molecular Function	GO:0005515	protein binding	NTSR1	IPI	UniProtKB:P30990	Human	PMID:17620610
Molecular Function	GO:0005515	protein binding	NTSR1	IPI	UniProtKB:P30990:PRO_0000019524	Human	PMID:23597562
Molecular Function	GO:0005515	protein binding	Ntsr1	IPI	RGD:621612	Rat	PMID:16708210|RGD:9727456
Molecular Function	GO:0044877	protein-containing complex binding	Ntsr1	IPI	RGD:70962	Rat	PMID:17188644|RGD:9743899
Cellular Component	GO:0030424	axon	Ntsr1	IDA		Rat	PMID:8876464|RGD:9743919
Cellular Component	GO:0043679	axon terminus	Ntsr1	IDA		Rat	PMID:8876464|RGD:9743919
Cellular Component	GO:0009986	cell surface	Ntsr1	IDA		Rat	PMID:17188644|RGD:9743899
Cellular Component	GO:0005737	cytoplasm	Ntsr1	IDA		Rat	PMID:8876464|RGD:9743919
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Ntsr1	IDA		Rat	PMID:9763490|RGD:9831116
Cellular Component	GO:0030425	dendrite	Ntsr1	IDA		Rat	PMID:10818259|RGD:9743847
Cellular Component	GO:0043198	dendritic shaft	Ntsr1	IDA		Rat	PMID:9763490|RGD:9831116
Cellular Component	GO:0043197	dendritic spine	Ntsr1	IDA		Rat	PMID:9763490|RGD:9831116
Cellular Component	GO:0005783	endoplasmic reticulum	Ntsr1	IDA		Rat	PMID:9763490|RGD:9831116
Cellular Component	GO:0005794	Golgi apparatus	Ntsr1	IDA		Rat	PMID:9763490|RGD:9831116
Cellular Component	GO:0045121	membrane raft	NTSR1	IDA		Human	PMID:21725197
Cellular Component	GO:0005739	mitochondrion	Ntsr1	IDA		Rat	PMID:9763490|RGD:9831116
Cellular Component	GO:0044309	neuron spine	Ntsr1	IDA		Rat	PMID:10818259|RGD:9743847
Cellular Component	GO:0043025	neuronal cell body	Ntsr1	IDA		Rat	PMID:9763490|RGD:9831116
Cellular Component	GO:0043204	perikaryon	Ntsr1	IDA		Rat	PMID:10818259|RGD:9743847
Cellular Component	GO:0043204	perikaryon	Ntsr1	IDA		Rat	PMID:11095496|RGD:9727454
Cellular Component	GO:0005886	plasma membrane	NTSR1	IMP		Human	PMID:8381365
Cellular Component	GO:0005886	plasma membrane	Ntsr1	IDA		Rat	PMID:22294115|RGD:9743848
Cellular Component	GO:0032280	symmetric synapse	Ntsr1	IDA		Rat	PMID:10818259|RGD:9743847
Cellular Component	GO:0045202	synapse	Ntsr1	IDA		Rat	PMID:9763490|RGD:9831116
Cellular Component	GO:0043195	terminal bouton	Ntsr1	IDA		Rat	PMID:10818259|RGD:9743847
Biological Process	GO:0008344	adult locomotory behavior	Ntsr1	IGI	MGI:MGI:98735	Mouse	PMID:15353215
Biological Process	GO:0070779	D-aspartate import across plasma membrane	Ntsr1	IDA		Rat	PMID:12123836|RGD:1566569
Biological Process	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	Ntsr1	IMP		Rat	PMID:15733655|RGD:9743979
Biological Process	GO:0071545	inositol phosphate catabolic process	Ntsr1	IMP		Rat	PMID:15707678|RGD:9743914
Biological Process	GO:0098712	L-glutamate import across plasma membrane	Ntsr1	IDA		Rat	PMID:12123836|RGD:1566569
Biological Process	GO:0007612	learning	Ntsr1	IMP		Rat	PMID:21946307|RGD:9743852
Biological Process	GO:0043066	negative regulation of apoptotic process	NTSR1	IMP		Human	PMID:21725197
Biological Process	GO:0051280	negative regulation of release of sequestered calcium ion into cytosol	Ntsr1	IMP		Rat	PMID:12084713|RGD:727385
Biological Process	GO:0003085	negative regulation of systemic arterial blood pressure	Ntsr1	IMP		Rat	PMID:22211865|RGD:9727449
Biological Process	GO:0007218	neuropeptide signaling pathway	NTSR1	IDA		Human	PMID:21725197
Biological Process	GO:0007218	neuropeptide signaling pathway	NTSR1	IGI	UniProtKB:P30990	Human	PMID:21806946
Biological Process	GO:0043065	positive regulation of apoptotic process	Ntsr1	IMP		Rat	PMID:18063561|RGD:9743970
Biological Process	GO:0090238	positive regulation of arachidonic acid secretion	Ntsr1	IMP		Rat	PMID:11852105|RGD:9743869
Biological Process	GO:2001259	positive regulation of cation channel activity	Ntsr1	IMP		Rat	PMID:19359367|RGD:9743912
Biological Process	GO:0014054	positive regulation of gamma-aminobutyric acid secretion	Ntsr1	IMP		Rat	PMID:15716398|RGD:9743972
Biological Process	GO:0010628	positive regulation of gene expression	NTSR1	IGI	UniProtKB:P30990	Human	PMID:21806946
Biological Process	GO:0014049	positive regulation of glutamate secretion	Ntsr1	IMP		Rat	PMID:18063561|RGD:9743970
Biological Process	GO:0097151	positive regulation of inhibitory postsynaptic potential	Ntsr1	IMP		Rat	PMID:15664687|RGD:9831120
Biological Process	GO:0060732	positive regulation of inositol phosphate biosynthetic process	Ntsr1	IMP		Rat	PMID:11861328|RGD:9743897
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	NTSR1	IGI	UniProtKB:P30990	Human	PMID:21806946
Biological Process	GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	Ntsr1	IMP		Rat	PMID:10799761|RGD:9743926
Biological Process	GO:0098900	regulation of action potential	Ntsr1	IDA		Rat	PMID:11274786|RGD:9743976
Biological Process	GO:0003254	regulation of membrane depolarization	Ntsr1	IMP		Rat	PMID:15120846|RGD:9743930
Biological Process	GO:0043576	regulation of respiratory gaseous exchange	Ntsr1	IMP		Rat	PMID:22211865|RGD:9727449
Biological Process	GO:0051930	regulation of sensory perception of pain	Ntsr1	IDA		Rat	PMID:18182046|RGD:9743925
Biological Process	GO:0051930	regulation of sensory perception of pain	Ntsr1	IDA		Rat	PMID:22396077|RGD:9743902
Biological Process	GO:0033993	response to lipid	Ntsr1	IDA		Rat	PMID:22306739|RGD:9743853
Biological Process	GO:0001659	temperature homeostasis	Ntsr1	IMP		Rat	PMID:7620825|RGD:9698456

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern