Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NUAK2
  • Mouse genes Nuak2
  • Rat genes Nuak2
  • Zfish genes nuak2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nuak2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	NUAK2	IDA		Human	PMID:14976552
Molecular Function	GO:0005524	ATP binding	Nuak2	IDA		Rat	PMID:11284715|RGD:68722
Molecular Function	GO:0000287	magnesium ion binding	NUAK2	IDA		Human	PMID:14976552
Molecular Function	GO:0000287	magnesium ion binding	Nuak2	IDA		Rat	PMID:11284715|RGD:68722
Molecular Function	GO:0005515	protein binding	NUAK2	IPI	UniProtKB:O95835	Human	PMID:19927127
Molecular Function	GO:0005515	protein binding	NUAK2	IPI	UniProtKB:Q4V328	Human	PMID:32296183
Molecular Function	GO:0004674	protein serine/threonine kinase activity	NUAK2	IDA		Human	PMID:14976552
Molecular Function	GO:0004674	protein serine/threonine kinase activity	NUAK2	IDA		Human	PMID:19927127
Molecular Function	GO:0004674	protein serine/threonine kinase activity	NUAK2	IMP		Human	PMID:32845958
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Nuak2	IDA		Rat	PMID:11284715|RGD:68722
Biological Process	GO:0030036	actin cytoskeleton organization	NUAK2	IDA		Human	PMID:14575707
Biological Process	GO:0042149	cellular response to glucose starvation	NUAK2	IDA		Human	PMID:14575707
Biological Process	GO:0042149	cellular response to glucose starvation	Nuak2	IDA		Rat	PMID:15893879|RGD:8553633
Biological Process	GO:0043066	negative regulation of apoptotic process	NUAK2	IDA		Human	PMID:15345718
Biological Process	GO:0034504	protein localization to nucleus	NUAK2	IMP		Human	PMID:32845958
Biological Process	GO:0006468	protein phosphorylation	NUAK2	IDA		Human	PMID:14976552
Biological Process	GO:0006468	protein phosphorylation	Nuak2	IDA		Rat	PMID:11284715|RGD:68722
Biological Process	GO:0035330	regulation of hippo signaling	NUAK2	IMP		Human	PMID:32845958

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern