Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NUDT15
  • Mouse genes Nudt15
  • Rat genes Nudt15
  • Zfish genes nudt15
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nudt15

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035539	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity	NUDT15	EXP		Human	PMID:22556419
Molecular Function	GO:0035539	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity	NUDT15	IDA		Human	PMID:22556419
Molecular Function	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity	NUDT15	IDA		Human	PMID:22556419
Molecular Function	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity	Nudt15	IDA		Mouse	PMID:12767940
Molecular Function	GO:0044715	8-oxo-dGDP phosphatase activity	NUDT15	EXP		Human	PMID:22556419
Molecular Function	GO:0047429	nucleoside triphosphate diphosphatase activity	NUDT15	IDA		Human	PMID:26238318
Molecular Function	GO:0005515	protein binding	NUDT15	IPI	UniProtKB:P12004	Human	PMID:19419956
Molecular Function	GO:0005515	protein binding	NUDT15	IPI	UniProtKB:P60520	Human	PMID:32296183
Biological Process	GO:0006203	dGTP catabolic process	NUDT15	IDA		Human	PMID:22556419
Biological Process	GO:0042262	DNA protection	NUDT15	IMP		Human	PMID:26878724
Biological Process	GO:0000278	mitotic cell cycle	NUDT15	IMP		Human	PMID:19419956
Biological Process	GO:1901292	nucleoside phosphate catabolic process	NUDT15	IDA		Human	PMID:26238318
Biological Process	GO:1901292	nucleoside phosphate catabolic process	NUDT15	IMP		Human	PMID:26878724
Biological Process	GO:0009217	purine deoxyribonucleoside triphosphate catabolic process	Nudt15	IDA		Mouse	PMID:12767940
Biological Process	GO:0006195	purine nucleotide catabolic process	NUDT15	IMP		Human	PMID:26878724
Biological Process	GO:0061136	regulation of proteasomal protein catabolic process	NUDT15	IMP		Human	PMID:19419956
Biological Process	GO:0000302	response to reactive oxygen species	Nudt15	IDA		Mouse	PMID:12767940
Biological Process	GO:0042178	xenobiotic catabolic process	NUDT15	IMP		Human	PMID:26878724

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern