Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NUMBL
  • Mouse genes Numbl
  • Rat genes Numbl
  • Zfish genes numbl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Numbl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	NUMBL	IPI	UniProtKB:P00533	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	NUMBL	IPI	UniProtKB:Q9NWB1	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	NUMBL	IPI	UniProtKB:Q9Y4K3	Human	PMID:20079715
Molecular Function	GO:0005515	protein binding	NUMBL	IPI	UniProtKB:Q6PJ21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	NUMBL	IPI	UniProtKB:O94985-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NUMBL	IPI	UniProtKB:P27986-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NUMBL	IPI	UniProtKB:Q00535	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	NUMBL	IPI	UniProtKB:P00533	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	Numbl	IPI	RGD:1309527	Rat	PMID:18299187|RGD:5507831
Molecular Function	GO:0005515	protein binding	Numbl	IPI	UniProtKB:Q5U303	Rat	PMID:18299187|RGD:5507831
Cellular Component	GO:0005737	cytoplasm	Numbl	IDA		Mouse	PMID:15598981
Cellular Component	GO:0005737	cytoplasm	Numbl	IDA		Mouse	PMID:10551880
Cellular Component	GO:0005737	cytoplasm	Numbl	IDA		Mouse	PMID:9169836
Cellular Component	GO:0005737	cytoplasm	numbl	IDA		Zfish	PMID:16493689
Cellular Component	GO:0098978	glutamatergic synapse	Numbl	IDA		Rat	PMID:16394100|RGD:2302413
Cellular Component	GO:0098978	glutamatergic synapse	Numbl	IMP		Rat	PMID:16394100|RGD:2302413
Biological Process	GO:0034332	adherens junction organization	Numbl	IGI	MGI:MGI:107423	Mouse	PMID:17589506
Biological Process	GO:0007409	axonogenesis	Numbl	IMP	MGI:MGI:2429686	Mouse	PMID:15598981
Biological Process	GO:0019221	cytokine-mediated signaling pathway	NUMBL	IDA		Human	PMID:18299187
Biological Process	GO:0007368	determination of left/right symmetry	numbl	IDA		Zfish	PMID:16701985
Biological Process	GO:0030900	forebrain development	Numbl	IMP	MGI:MGI:2429686	Mouse	PMID:14687546
Biological Process	GO:0021670	lateral ventricle development	Numbl	IMP		Mouse	MGI:MGI:3763347|PMID:17174898
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	numbl	IGI	ZFIN:ZDB-GENE-990415-47	Zfish	PMID:16701985
Biological Process	GO:0007399	nervous system development	Numbl	IMP	MGI:MGI:2429686	Mouse	PMID:14687546
Biological Process	GO:0021849	neuroblast division in subventricular zone	Numbl	IMP		Mouse	MGI:MGI:3763347|PMID:17174898
Biological Process	GO:0007405	neuroblast proliferation	Numbl	IGI	MGI:MGI:107423	Mouse	PMID:12410312
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	Numbl	IMP		Rat	PMID:16394100|RGD:2302413
Biological Process	GO:0050769	positive regulation of neurogenesis	Numbl	IMP		Mouse	MGI:MGI:2389562|PMID:12410312
Biological Process	GO:0060319	primitive erythrocyte differentiation	numbl	IMP	ZFIN:ZDB-MRPHLNO-110114-2	Zfish	PMID:21179188
Biological Process	GO:0060319	primitive erythrocyte differentiation	numbl	IGI	ZFIN:ZDB-MRPHLNO-110203-2	Zfish	PMID:21179188
Biological Process	GO:0019538	protein metabolic process	NUMBL	IDA		Human	PMID:20079715
Biological Process	GO:0150052	regulation of postsynapse assembly	Numbl	IDA		Rat	PMID:16394100|RGD:2302413
Biological Process	GO:0150052	regulation of postsynapse assembly	Numbl	IMP		Rat	PMID:16394100|RGD:2302413

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern