Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NUP214
  • Mouse genes Nup214
  • Rat genes Nup214
  • Zfish genes nup214
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nup214

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005049	nuclear export signal receptor activity	NUP214	IDA		Human	PMID:10358091
Molecular Function	GO:0008139	nuclear localization sequence binding	Nup214	IDA		Rat	PMID:7878057|RGD:729014
Molecular Function	GO:0005515	protein binding	NUP214	IPI	UniProtKB:Q9H4D5	Human	PMID:11545741
Molecular Function	GO:0005515	protein binding	NUP214	IPI	UniProtKB:Q9HAV4	Human	PMID:11777942
Molecular Function	GO:0005515	protein binding	NUP214	IPI	UniProtKB:P26651	Human	PMID:14766228
Molecular Function	GO:0005515	protein binding	NUP214	IPI	UniProtKB:Q99567	Human	PMID:30543681
Molecular Function	GO:0005515	protein binding	Nup214	IPI	RGD:620182	Rat	PMID:9166401|RGD:633582
Molecular Function	GO:0017056	structural constituent of nuclear pore	Nup214	IMP	MGI:MGI:2441651	Mouse	PMID:8896451
Cellular Component	GO:1990876	cytoplasmic side of nuclear pore	NUP214	IDA		Human	PMID:8108440
Cellular Component	GO:0005635	nuclear envelope	NUP214	IDA		Human	PMID:24315095
Cellular Component	GO:0005635	nuclear envelope	Nup214	IDA		Rat	PMID:9166401|RGD:633582
Biological Process	GO:0000278	mitotic cell cycle	Nup214	IDA		Rat	PMID:10362555|RGD:10401210
Biological Process	GO:0006406	mRNA export from nucleus	NUP214	IMP		Human	PMID:10557333
Biological Process	GO:0006406	mRNA export from nucleus	Nup214	IMP	MGI:MGI:2441651	Mouse	PMID:8896451
Biological Process	GO:0007219	Notch signaling pathway	nup214	IMP	ZFIN:ZDB-MRPHLNO-200117-4	Zfish	PMID:31186352
Biological Process	GO:0006611	protein export from nucleus	NUP214	IMP		Human	PMID:12191473
Biological Process	GO:0006606	protein import into nucleus	Nup214	IMP	MGI:MGI:2441651	Mouse	PMID:8896451
Biological Process	GO:0051726	regulation of cell cycle	Nup214	IMP	MGI:MGI:2441651	Mouse	PMID:8896451
Biological Process	GO:0046822	regulation of nucleocytoplasmic transport	NUP214	IMP		Human	PMID:11000203

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern