Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes NVL
  • Mouse genes Nvl
  • Rat genes Nvl
  • Zfish genes nvl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Nvl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	NVL	IMP		Human	PMID:22226966
Molecular Function	GO:1990275	preribosome binding	NVL	IDA		Human	PMID:16782053
Molecular Function	GO:0005515	protein binding	NVL	IPI	UniProtKB:P46777	Human	PMID:15469983
Molecular Function	GO:0005515	protein binding	NVL	IPI	UniProtKB:P42285	Human	PMID:16782053
Molecular Function	GO:0005515	protein binding	NVL	IPI	UniProtKB:O14746	Human	PMID:22226966
Molecular Function	GO:0005515	protein binding	NVL	IPI	UniProtKB:P42285	Human	PMID:26166824
Molecular Function	GO:0005515	protein binding	NVL	IPI	UniProtKB:Q6RFH5	Human	PMID:28416111
Molecular Function	GO:0005515	protein binding	NVL	IPI	UniProtKB:P42285	Human	PMID:31358741
Molecular Function	GO:0003723	RNA binding	NVL	HDA		Human	PMID:22658674
Cellular Component	GO:0016020	membrane	NVL	HDA		Human	PMID:19946888
Cellular Component	GO:0005730	nucleolus	NVL	IDA		Human	PMID:26456651
Cellular Component	GO:0005730	nucleolus	NVL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	NVL	IDA		Human	PMID:15469983
Cellular Component	GO:0005730	nucleolus	NVL	IDA		Human	PMID:22226966
Cellular Component	GO:0005654	nucleoplasm	NVL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	NVL	IDA		Human	PMID:15469983
Cellular Component	GO:0005634	nucleus	NVL	IDA		Human	PMID:16782053
Cellular Component	GO:0005697	telomerase holoenzyme complex	NVL	IDA		Human	PMID:22226966
Biological Process	GO:0032092	positive regulation of protein binding	NVL	IDA		Human	PMID:29107693
Biological Process	GO:0051973	positive regulation of telomerase activity	NVL	IMP		Human	PMID:22226966
Biological Process	GO:1904749	regulation of protein localization to nucleolus	NVL	IDA		Human	PMID:29107693
Biological Process	GO:0042273	ribosomal large subunit biogenesis	NVL	IDA		Human	PMID:26166824
Biological Process	GO:0042273	ribosomal large subunit biogenesis	NVL	IMP		Human	PMID:26456651
Biological Process	GO:0042254	ribosome biogenesis	NVL	IMP		Human	PMID:15469983
Biological Process	GO:0042254	ribosome biogenesis	NVL	IMP		Human	PMID:16782053
Biological Process	GO:0006364	rRNA processing	NVL	IDA		Human	PMID:29107693

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern